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Protein
Submitted name:

Nrf1 protein

Gene

Nrf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Nrf1 proteinImported
Submitted name:
Nuclear respiratory factor 1Imported
Submitted name:
Nuclear respiratory factor 1, isoform CRA_cImported
Gene namesi
Name:Nrf1Imported
ORF Names:mCG_8300Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1332235. Nrf1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiENSMUSG00000058440.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

MINTiMINT-4123692.
STRINGi10090.ENSMUSP00000065568.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini75 – 283209Nrf1_DNA-bindInterPro annotationAdd
BLAST
Domaini450 – 52677YchF-GTPase_CInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG410IDYK. Eukaryota.
ENOG410XNU7. LUCA.
GeneTreeiENSGT00390000006835.
HOGENOMiHOG000273898.
HOVERGENiHBG003062.
OrthoDBiEOG091G0BDT.
TreeFamiTF105308.

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
InterProiIPR012675. Beta-grasp_dom.
IPR013029. DUF933.
IPR019525. Nrf1_NLS/DNA-bd_dimer.
IPR012676. TGS-like.
[Graphical view]
PfamiPF10491. Nrf1_DNA-bind. 1 hit.
PF06071. YchF-GTPase_C. 1 hit.
[Graphical view]
SUPFAMiSSF81271. SSF81271. 1 hit.

Sequencei

Sequence statusi: Complete.

Q99K73-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEHGVTQTE HMATIEAHAV AQQVQQVHVA TYTEHSMLSA DEDSPSSPED
60 70 80 90 100
TSYDDSDILN STAADEVTAH LAAAGPVGMA AAAAVATGKK RKRPHVFESN
110 120 130 140 150
PSIRKRQQTR LLRKLRATLD EYTTRVGQQA IVLCISPSKP NPVFKVFGAA
160 170 180 190 200
PLENVVRKYK SMILEDLESA LAEHAPAPQE VNSELPPLTI DGIPVSVDKM
210 220 230 240 250
TQAQLRAFIP EMLKYSTGRG KPGWGKESCK PIWWPEDIPW ANVRSDVRTE
260 270 280 290 300
EQKQRVSWTQ ALRTIVKNCY KQHGREDLLY AFEDQQTQTQ ATTTHSIAHL
310 320 330 340 350
VPSQTVVQTF SNPDGTVSLI QVGTGATVAT LADASELPTT VTVAQVNYSA
360 370 380 390 400
VADGEVEQNW ATLQGGEMTI QTTQASEATQ AVASLAEAAV AASQEMQQGA
410 420 430 440 450
TVTMALNSEA AAHAVATLAE ATLQGGGQIV LSGETAAAVG ALTGVQDANG
460 470 480 490 500
PDGVHAWTIS KAVTAPQAAG KIHTDFGKGF IMAEVMKDED LKEESSENAA
510 520 530
KAAGKYKQQG RAYVVEDGDI IFFKFNSPQQ LKKK
Length:534
Mass (Da):57,283
Last modified:June 1, 2001 - v1
Checksum:i3B952C3FF201C2FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC134897 Genomic DNA. No translation available.
AC153632 Genomic DNA. No translation available.
BC005410 mRNA. Translation: AAH05410.1.
CH466533 Genomic DNA. Translation: EDL13756.1.
RefSeqiNP_001157699.1. NM_001164227.1.
XP_006505069.1. XM_006505006.2.
UniGeneiMm.259258.

Genome annotation databases

EnsembliENSMUST00000069808; ENSMUSP00000065568; ENSMUSG00000058440.
ENSMUST00000115206; ENSMUSP00000110860; ENSMUSG00000058440.
GeneIDi18181.
UCSCiuc009bet.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC134897 Genomic DNA. No translation available.
AC153632 Genomic DNA. No translation available.
BC005410 mRNA. Translation: AAH05410.1.
CH466533 Genomic DNA. Translation: EDL13756.1.
RefSeqiNP_001157699.1. NM_001164227.1.
XP_006505069.1. XM_006505006.2.
UniGeneiMm.259258.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-4123692.
STRINGi10090.ENSMUSP00000065568.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000069808; ENSMUSP00000065568; ENSMUSG00000058440.
ENSMUST00000115206; ENSMUSP00000110860; ENSMUSG00000058440.
GeneIDi18181.
UCSCiuc009bet.1. mouse.

Organism-specific databases

CTDi4899.
MGIiMGI:1332235. Nrf1.

Phylogenomic databases

eggNOGiENOG410IDYK. Eukaryota.
ENOG410XNU7. LUCA.
GeneTreeiENSGT00390000006835.
HOGENOMiHOG000273898.
HOVERGENiHBG003062.
OrthoDBiEOG091G0BDT.
TreeFamiTF105308.

Miscellaneous databases

ChiTaRSiNrf1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000058440.

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
InterProiIPR012675. Beta-grasp_dom.
IPR013029. DUF933.
IPR019525. Nrf1_NLS/DNA-bd_dimer.
IPR012676. TGS-like.
[Graphical view]
PfamiPF10491. Nrf1_DNA-bind. 1 hit.
PF06071. YchF-GTPase_C. 1 hit.
[Graphical view]
SUPFAMiSSF81271. SSF81271. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ99K73_MOUSE
AccessioniPrimary (citable) accession number: Q99K73
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.