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Protein

Syntenin-2

Gene

Sdcbp2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein C-terminus binding Source: UniProtKB
  2. protein heterodimerization activity Source: UniProtKB
  3. protein homodimerization activity Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Syntenin-2
Alternative name(s):
Syndecan-binding protein 2
Gene namesi
Name:Sdcbp2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 2

Organism-specific databases

MGIiMGI:2385156. Sdcbp2.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB
  2. extracellular vesicular exosome Source: MGI
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 292292Syntenin-2PRO_0000184005Add
BLAST

Proteomic databases

MaxQBiQ99JZ0.
PRIDEiQ99JZ0.

PTM databases

PhosphoSiteiQ99JZ0.

Expressioni

Gene expression databases

BgeeiQ99JZ0.
CleanExiMM_SDCBP2.
ExpressionAtlasiQ99JZ0. baseline and differential.
GenevestigatoriQ99JZ0.

Interactioni

Subunit structurei

Monomer and homodimer. Interacts with SDCBP (By similarity).By similarity

Protein-protein interaction databases

MINTiMINT-140851.

Structurei

3D structure databases

ProteinModelPortaliQ99JZ0.
SMRiQ99JZ0. Positions 107-265.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini108 – 18780PDZ 1PROSITE-ProRule annotationAdd
BLAST
Domaini192 – 26776PDZ 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 PDZ (DHR) domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG140434.
GeneTreeiENSGT00390000014465.
HOGENOMiHOG000231604.
HOVERGENiHBG053211.
InParanoidiQ99JZ0.
OMAiHTMDHSI.
OrthoDBiEOG75MVWZ.
PhylomeDBiQ99JZ0.
TreeFamiTF327131.

Family and domain databases

Gene3Di2.30.42.10. 2 hits.
InterProiIPR001478. PDZ.
[Graphical view]
PfamiPF00595. PDZ. 2 hits.
[Graphical view]
SMARTiSM00228. PDZ. 2 hits.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 2 hits.
PROSITEiPS50106. PDZ. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q99JZ0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVLYPSLED LKVGQVIQAQ GRASPTMPTL PAPMASAPPL SELYPNLAEL
60 70 80 90 100
ESYMGLSLSS QEVQKNLTQI PDSDNMVVTS PGPGQVVAPV SGNNLGILRA
110 120 130 140 150
EIKPGVREIH LCKDERGKTG LRLQAVDKGL FVQLVQANTP ASLVGLRFGD
160 170 180 190 200
QILQIDGCDC AGWNTHKAHK VLKKASAEKI VMVIRDRPFQ RTVTMHKDSS
210 220 230 240 250
GQVGFSIKKG KIVSVVKGSS AARNGLLTNH YVCEVNGQNV IGLKDKKVTE
260 270 280 290
ILTTAGDVIT LTIIPTVIYE HMIKRLSPLL LHHTMDHSIP DT
Length:292
Mass (Da):31,565
Last modified:June 1, 2001 - v1
Checksum:iC694316BC0A0931D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC005556 mRNA. Translation: AAH05556.1.
CCDSiCCDS16870.1.
RefSeqiNP_663510.1. NM_145535.2.
XP_006499367.1. XM_006499304.1.
XP_006499368.1. XM_006499305.1.
UniGeneiMm.32068.

Genome annotation databases

EnsembliENSMUST00000028950; ENSMUSP00000028950; ENSMUSG00000027456.
GeneIDi228765.
KEGGimmu:228765.
UCSCiuc008nec.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC005556 mRNA. Translation: AAH05556.1.
CCDSiCCDS16870.1.
RefSeqiNP_663510.1. NM_145535.2.
XP_006499367.1. XM_006499304.1.
XP_006499368.1. XM_006499305.1.
UniGeneiMm.32068.

3D structure databases

ProteinModelPortaliQ99JZ0.
SMRiQ99JZ0. Positions 107-265.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-140851.

PTM databases

PhosphoSiteiQ99JZ0.

Proteomic databases

MaxQBiQ99JZ0.
PRIDEiQ99JZ0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000028950; ENSMUSP00000028950; ENSMUSG00000027456.
GeneIDi228765.
KEGGimmu:228765.
UCSCiuc008nec.1. mouse.

Organism-specific databases

CTDi27111.
MGIiMGI:2385156. Sdcbp2.

Phylogenomic databases

eggNOGiNOG140434.
GeneTreeiENSGT00390000014465.
HOGENOMiHOG000231604.
HOVERGENiHBG053211.
InParanoidiQ99JZ0.
OMAiHTMDHSI.
OrthoDBiEOG75MVWZ.
PhylomeDBiQ99JZ0.
TreeFamiTF327131.

Miscellaneous databases

NextBioi379104.
PROiQ99JZ0.
SOURCEiSearch...

Gene expression databases

BgeeiQ99JZ0.
CleanExiMM_SDCBP2.
ExpressionAtlasiQ99JZ0. baseline and differential.
GenevestigatoriQ99JZ0.

Family and domain databases

Gene3Di2.30.42.10. 2 hits.
InterProiIPR001478. PDZ.
[Graphical view]
PfamiPF00595. PDZ. 2 hits.
[Graphical view]
SMARTiSM00228. PDZ. 2 hits.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 2 hits.
PROSITEiPS50106. PDZ. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiSDCB2_MOUSE
AccessioniPrimary (citable) accession number: Q99JZ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 2, 2002
Last sequence update: June 1, 2001
Last modified: February 4, 2015
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.