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Q99JZ0

- SDCB2_MOUSE

UniProt

Q99JZ0 - SDCB2_MOUSE

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Protein

Syntenin-2

Gene

Sdcbp2

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein C-terminus binding Source: UniProtKB
  2. protein heterodimerization activity Source: UniProtKB
  3. protein homodimerization activity Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Syntenin-2
Alternative name(s):
Syndecan-binding protein 2
Gene namesi
Name:Sdcbp2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 2

Organism-specific databases

MGIiMGI:2385156. Sdcbp2.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB
  2. extracellular vesicular exosome Source: Ensembl
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 292292Syntenin-2PRO_0000184005Add
BLAST

Proteomic databases

MaxQBiQ99JZ0.
PRIDEiQ99JZ0.

PTM databases

PhosphoSiteiQ99JZ0.

Expressioni

Gene expression databases

BgeeiQ99JZ0.
CleanExiMM_SDCBP2.
ExpressionAtlasiQ99JZ0. baseline and differential.
GenevestigatoriQ99JZ0.

Interactioni

Subunit structurei

Monomer and homodimer. Interacts with SDCBP (By similarity).By similarity

Protein-protein interaction databases

MINTiMINT-140851.

Structurei

3D structure databases

ProteinModelPortaliQ99JZ0.
SMRiQ99JZ0. Positions 107-265.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini108 – 18780PDZ 1PROSITE-ProRule annotationAdd
BLAST
Domaini192 – 26776PDZ 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 PDZ (DHR) domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG140434.
GeneTreeiENSGT00390000014465.
HOGENOMiHOG000231604.
HOVERGENiHBG053211.
InParanoidiQ99JZ0.
OMAiHTMDHSI.
OrthoDBiEOG75MVWZ.
PhylomeDBiQ99JZ0.
TreeFamiTF327131.

Family and domain databases

Gene3Di2.30.42.10. 2 hits.
InterProiIPR001478. PDZ.
[Graphical view]
PfamiPF00595. PDZ. 2 hits.
[Graphical view]
SMARTiSM00228. PDZ. 2 hits.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 2 hits.
PROSITEiPS50106. PDZ. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q99JZ0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVLYPSLED LKVGQVIQAQ GRASPTMPTL PAPMASAPPL SELYPNLAEL
60 70 80 90 100
ESYMGLSLSS QEVQKNLTQI PDSDNMVVTS PGPGQVVAPV SGNNLGILRA
110 120 130 140 150
EIKPGVREIH LCKDERGKTG LRLQAVDKGL FVQLVQANTP ASLVGLRFGD
160 170 180 190 200
QILQIDGCDC AGWNTHKAHK VLKKASAEKI VMVIRDRPFQ RTVTMHKDSS
210 220 230 240 250
GQVGFSIKKG KIVSVVKGSS AARNGLLTNH YVCEVNGQNV IGLKDKKVTE
260 270 280 290
ILTTAGDVIT LTIIPTVIYE HMIKRLSPLL LHHTMDHSIP DT
Length:292
Mass (Da):31,565
Last modified:June 1, 2001 - v1
Checksum:iC694316BC0A0931D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC005556 mRNA. Translation: AAH05556.1.
CCDSiCCDS16870.1.
RefSeqiNP_663510.1. NM_145535.2.
XP_006499367.1. XM_006499304.1.
XP_006499368.1. XM_006499305.1.
UniGeneiMm.32068.

Genome annotation databases

EnsembliENSMUST00000028950; ENSMUSP00000028950; ENSMUSG00000027456.
GeneIDi228765.
KEGGimmu:228765.
UCSCiuc008nec.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC005556 mRNA. Translation: AAH05556.1 .
CCDSi CCDS16870.1.
RefSeqi NP_663510.1. NM_145535.2.
XP_006499367.1. XM_006499304.1.
XP_006499368.1. XM_006499305.1.
UniGenei Mm.32068.

3D structure databases

ProteinModelPortali Q99JZ0.
SMRi Q99JZ0. Positions 107-265.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-140851.

PTM databases

PhosphoSitei Q99JZ0.

Proteomic databases

MaxQBi Q99JZ0.
PRIDEi Q99JZ0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000028950 ; ENSMUSP00000028950 ; ENSMUSG00000027456 .
GeneIDi 228765.
KEGGi mmu:228765.
UCSCi uc008nec.1. mouse.

Organism-specific databases

CTDi 27111.
MGIi MGI:2385156. Sdcbp2.

Phylogenomic databases

eggNOGi NOG140434.
GeneTreei ENSGT00390000014465.
HOGENOMi HOG000231604.
HOVERGENi HBG053211.
InParanoidi Q99JZ0.
OMAi HTMDHSI.
OrthoDBi EOG75MVWZ.
PhylomeDBi Q99JZ0.
TreeFami TF327131.

Miscellaneous databases

NextBioi 379104.
PROi Q99JZ0.
SOURCEi Search...

Gene expression databases

Bgeei Q99JZ0.
CleanExi MM_SDCBP2.
ExpressionAtlasi Q99JZ0. baseline and differential.
Genevestigatori Q99JZ0.

Family and domain databases

Gene3Di 2.30.42.10. 2 hits.
InterProi IPR001478. PDZ.
[Graphical view ]
Pfami PF00595. PDZ. 2 hits.
[Graphical view ]
SMARTi SM00228. PDZ. 2 hits.
[Graphical view ]
SUPFAMi SSF50156. SSF50156. 2 hits.
PROSITEi PS50106. PDZ. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiSDCB2_MOUSE
AccessioniPrimary (citable) accession number: Q99JZ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 2, 2002
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3