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Q99JZ0

- SDCB2_MOUSE

UniProt

Q99JZ0 - SDCB2_MOUSE

Protein

Syntenin-2

Gene

Sdcbp2

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein C-terminus binding Source: UniProtKB
    2. protein heterodimerization activity Source: UniProtKB
    3. protein homodimerization activity Source: UniProtKB

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Syntenin-2
    Alternative name(s):
    Syndecan-binding protein 2
    Gene namesi
    Name:Sdcbp2
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 2

    Organism-specific databases

    MGIiMGI:2385156. Sdcbp2.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 292292Syntenin-2PRO_0000184005Add
    BLAST

    Proteomic databases

    MaxQBiQ99JZ0.
    PRIDEiQ99JZ0.

    PTM databases

    PhosphoSiteiQ99JZ0.

    Expressioni

    Gene expression databases

    ArrayExpressiQ99JZ0.
    BgeeiQ99JZ0.
    CleanExiMM_SDCBP2.
    GenevestigatoriQ99JZ0.

    Interactioni

    Subunit structurei

    Monomer and homodimer. Interacts with SDCBP By similarity.By similarity

    Protein-protein interaction databases

    MINTiMINT-140851.

    Structurei

    3D structure databases

    ProteinModelPortaliQ99JZ0.
    SMRiQ99JZ0. Positions 107-265.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini108 – 18780PDZ 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini192 – 26776PDZ 2PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 2 PDZ (DHR) domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiNOG140434.
    GeneTreeiENSGT00390000014465.
    HOGENOMiHOG000231604.
    HOVERGENiHBG053211.
    InParanoidiQ99JZ0.
    OMAiHTMDHSI.
    OrthoDBiEOG75MVWZ.
    PhylomeDBiQ99JZ0.
    TreeFamiTF327131.

    Family and domain databases

    Gene3Di2.30.42.10. 2 hits.
    InterProiIPR001478. PDZ.
    [Graphical view]
    PfamiPF00595. PDZ. 2 hits.
    [Graphical view]
    SMARTiSM00228. PDZ. 2 hits.
    [Graphical view]
    SUPFAMiSSF50156. SSF50156. 2 hits.
    PROSITEiPS50106. PDZ. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q99JZ0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSVLYPSLED LKVGQVIQAQ GRASPTMPTL PAPMASAPPL SELYPNLAEL    50
    ESYMGLSLSS QEVQKNLTQI PDSDNMVVTS PGPGQVVAPV SGNNLGILRA 100
    EIKPGVREIH LCKDERGKTG LRLQAVDKGL FVQLVQANTP ASLVGLRFGD 150
    QILQIDGCDC AGWNTHKAHK VLKKASAEKI VMVIRDRPFQ RTVTMHKDSS 200
    GQVGFSIKKG KIVSVVKGSS AARNGLLTNH YVCEVNGQNV IGLKDKKVTE 250
    ILTTAGDVIT LTIIPTVIYE HMIKRLSPLL LHHTMDHSIP DT 292
    Length:292
    Mass (Da):31,565
    Last modified:June 1, 2001 - v1
    Checksum:iC694316BC0A0931D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC005556 mRNA. Translation: AAH05556.1.
    CCDSiCCDS16870.1.
    RefSeqiNP_663510.1. NM_145535.2.
    XP_006499367.1. XM_006499304.1.
    XP_006499368.1. XM_006499305.1.
    UniGeneiMm.32068.

    Genome annotation databases

    EnsembliENSMUST00000028950; ENSMUSP00000028950; ENSMUSG00000027456.
    GeneIDi228765.
    KEGGimmu:228765.
    UCSCiuc008nec.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC005556 mRNA. Translation: AAH05556.1 .
    CCDSi CCDS16870.1.
    RefSeqi NP_663510.1. NM_145535.2.
    XP_006499367.1. XM_006499304.1.
    XP_006499368.1. XM_006499305.1.
    UniGenei Mm.32068.

    3D structure databases

    ProteinModelPortali Q99JZ0.
    SMRi Q99JZ0. Positions 107-265.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-140851.

    PTM databases

    PhosphoSitei Q99JZ0.

    Proteomic databases

    MaxQBi Q99JZ0.
    PRIDEi Q99JZ0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000028950 ; ENSMUSP00000028950 ; ENSMUSG00000027456 .
    GeneIDi 228765.
    KEGGi mmu:228765.
    UCSCi uc008nec.1. mouse.

    Organism-specific databases

    CTDi 27111.
    MGIi MGI:2385156. Sdcbp2.

    Phylogenomic databases

    eggNOGi NOG140434.
    GeneTreei ENSGT00390000014465.
    HOGENOMi HOG000231604.
    HOVERGENi HBG053211.
    InParanoidi Q99JZ0.
    OMAi HTMDHSI.
    OrthoDBi EOG75MVWZ.
    PhylomeDBi Q99JZ0.
    TreeFami TF327131.

    Miscellaneous databases

    NextBioi 379104.
    PROi Q99JZ0.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q99JZ0.
    Bgeei Q99JZ0.
    CleanExi MM_SDCBP2.
    Genevestigatori Q99JZ0.

    Family and domain databases

    Gene3Di 2.30.42.10. 2 hits.
    InterProi IPR001478. PDZ.
    [Graphical view ]
    Pfami PF00595. PDZ. 2 hits.
    [Graphical view ]
    SMARTi SM00228. PDZ. 2 hits.
    [Graphical view ]
    SUPFAMi SSF50156. SSF50156. 2 hits.
    PROSITEi PS50106. PDZ. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

    Entry informationi

    Entry nameiSDCB2_MOUSE
    AccessioniPrimary (citable) accession number: Q99JZ0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 2, 2002
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3