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Q99JX1

- TAF11_MOUSE

UniProt

Q99JX1 - TAF11_MOUSE

Protein

Transcription initiation factor TFIID subunit 11

Gene

Taf11

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 101 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    Core TAFII present in both of the previously described TFIID species which either lack or contain TAFII30 (TFIID alpha and TFIID beta respectively).By similarity

    GO - Molecular functioni

    1. DNA binding Source: MGI
    2. transcription coactivator activity Source: Ensembl

    GO - Biological processi

    1. positive regulation by host of viral transcription Source: Ensembl
    2. regulation of transcription, DNA-templated Source: UniProtKB-KW
    3. transcription initiation from RNA polymerase II promoter Source: InterPro

    Keywords - Biological processi

    Transcription, Transcription regulation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Transcription initiation factor TFIID subunit 11
    Alternative name(s):
    TFIID subunit p30-beta
    Transcription initiation factor TFIID 28 kDa subunit
    Short name:
    TAF(II)28
    Short name:
    TAFII-28
    Short name:
    TAFII28
    Gene namesi
    Name:Taf11
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 17

    Organism-specific databases

    MGIiMGI:1916026. Taf11.

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. nucleus Source: MGI
    2. transcription factor TFIID complex Source: MGI

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 211211Transcription initiation factor TFIID subunit 11PRO_0000118903Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei1 – 11N-acetylmethionineBy similarity

    Keywords - PTMi

    Acetylation

    Proteomic databases

    PRIDEiQ99JX1.

    PTM databases

    PhosphoSiteiQ99JX1.

    Expressioni

    Gene expression databases

    BgeeiQ99JX1.
    GenevestigatoriQ99JX1.

    Interactioni

    Subunit structurei

    TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs).By similarity

    Protein-protein interaction databases

    IntActiQ99JX1. 1 interaction.

    Structurei

    3D structure databases

    ProteinModelPortaliQ99JX1.
    SMRiQ99JX1. Positions 113-201.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domaini

    TBP and TAFII18 bind to distinct domains of TAFII28.By similarity

    Sequence similaritiesi

    Belongs to the TAF11 family.Curated

    Phylogenomic databases

    eggNOGiCOG5251.
    GeneTreeiENSGT00390000013228.
    HOGENOMiHOG000006355.
    HOVERGENiHBG079228.
    InParanoidiQ99JX1.
    KOiK03135.
    OMAiKHKKITF.
    OrthoDBiEOG7VDXQT.
    PhylomeDBiQ99JX1.
    TreeFamiTF315132.

    Family and domain databases

    Gene3Di1.10.20.10. 1 hit.
    InterProiIPR009072. Histone-fold.
    IPR006809. TAFII28.
    [Graphical view]
    PANTHERiPTHR13218. PTHR13218. 1 hit.
    PfamiPF04719. TAFII28. 1 hit.
    [Graphical view]
    SUPFAMiSSF47113. SSF47113. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q99JX1-1 [UniParc]FASTAAdd to Basket

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    MDNLGESPTD KGGEPGESEE TRATPGALVA ADTEGIPEET DRDGDADLKE    50
    AAAEESELKS QDVSDVTAAE RENSSLLTPA AKKLKLDIKD KKEKKQKVDE 100
    DEIQKMQILV SSFSEEQLNR YEMYRRSAFP KAAIKRLIQS ITGTSVSQNV 150
    VIAMSGISKV FVGEVVEEAL DVCEKWGETP PLQPKHMREA VRRLKSKGQI 200
    PNSKHKKITF F 211
    Length:211
    Mass (Da):23,333
    Last modified:June 1, 2001 - v1
    Checksum:iA19D3778C07513E7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK004168 mRNA. Translation: BAB23203.1.
    AK050689 mRNA. Translation: BAC34381.1.
    AK133851 mRNA. Translation: BAE21886.1.
    BC005603 mRNA. Translation: AAH05603.1.
    CCDSiCCDS28571.1.
    RefSeqiNP_081112.1. NM_026836.2.
    XP_006524924.1. XM_006524861.1.
    XP_006524925.1. XM_006524862.1.
    XP_006536847.1. XM_006536784.1.
    XP_006536848.1. XM_006536785.1.
    UniGeneiMm.267998.

    Genome annotation databases

    EnsembliENSMUST00000025057; ENSMUSP00000025057; ENSMUSG00000024218.
    ENSMUST00000114848; ENSMUSP00000110498; ENSMUSG00000024218.
    GeneIDi68776.
    KEGGimmu:68776.
    UCSCiuc008bpu.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK004168 mRNA. Translation: BAB23203.1 .
    AK050689 mRNA. Translation: BAC34381.1 .
    AK133851 mRNA. Translation: BAE21886.1 .
    BC005603 mRNA. Translation: AAH05603.1 .
    CCDSi CCDS28571.1.
    RefSeqi NP_081112.1. NM_026836.2.
    XP_006524924.1. XM_006524861.1.
    XP_006524925.1. XM_006524862.1.
    XP_006536847.1. XM_006536784.1.
    XP_006536848.1. XM_006536785.1.
    UniGenei Mm.267998.

    3D structure databases

    ProteinModelPortali Q99JX1.
    SMRi Q99JX1. Positions 113-201.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q99JX1. 1 interaction.

    PTM databases

    PhosphoSitei Q99JX1.

    Proteomic databases

    PRIDEi Q99JX1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000025057 ; ENSMUSP00000025057 ; ENSMUSG00000024218 .
    ENSMUST00000114848 ; ENSMUSP00000110498 ; ENSMUSG00000024218 .
    GeneIDi 68776.
    KEGGi mmu:68776.
    UCSCi uc008bpu.1. mouse.

    Organism-specific databases

    CTDi 6882.
    MGIi MGI:1916026. Taf11.

    Phylogenomic databases

    eggNOGi COG5251.
    GeneTreei ENSGT00390000013228.
    HOGENOMi HOG000006355.
    HOVERGENi HBG079228.
    InParanoidi Q99JX1.
    KOi K03135.
    OMAi KHKKITF.
    OrthoDBi EOG7VDXQT.
    PhylomeDBi Q99JX1.
    TreeFami TF315132.

    Miscellaneous databases

    ChiTaRSi Taf11. mouse.
    NextBioi 327906.
    PROi Q99JX1.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q99JX1.
    Genevestigatori Q99JX1.

    Family and domain databases

    Gene3Di 1.10.20.10. 1 hit.
    InterProi IPR009072. Histone-fold.
    IPR006809. TAFII28.
    [Graphical view ]
    PANTHERi PTHR13218. PTHR13218. 1 hit.
    Pfami PF04719. TAFII28. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47113. SSF47113. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Embryo.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/N.
      Tissue: Mammary tumor.

    Entry informationi

    Entry nameiTAF11_MOUSE
    AccessioniPrimary (citable) accession number: Q99JX1
    Secondary accession number(s): Q3UZH1, Q9CT98
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 12, 2005
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 101 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3