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Protein
Submitted name:

Glycine receptor alpha 3

Gene

Glra3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channelUniRule annotationSAAS annotation, ReceptorImported
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Glycine receptor alpha 3Imported
Gene namesi
Name:Glra3Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi621229 Glra3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei271 – 293HelicalSequence analysisAdd BLAST23
Transmembranei334 – 357HelicalSequence analysisAdd BLAST24
Transmembranei450 – 470HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

GenevisibleiQ99JC9 RN

Structurei

3D structure databases

ProteinModelPortaliQ99JC9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 269Neur_chan_LBDInterPro annotationAdd BLAST208
Domaini276 – 368Neur_chan_membInterPro annotationAdd BLAST93

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG051707
KOiK05195
PhylomeDBiQ99JC9

Family and domain databases

Gene3Di2.70.170.101 hit
InterProiView protein in InterPro
IPR006028 GABAA/Glycine_rcpt
IPR008127 Glycine_rcpt_A
IPR008130 Glycine_rcpt_A3
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
IPR036719 Neuro-gated_channel_TM_sf
IPR006029 Neurotrans-gated_channel_TM
IPR018000 Neurotransmitter_ion_chnl_CS
PANTHERiPTHR18945 PTHR18945, 1 hit
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 1 hit
PF02932 Neur_chan_memb, 1 hit
PRINTSiPR00253 GABAARECEPTR
PR01673 GLYRALPHA
PR01676 GLYRALPHA3
PR00252 NRIONCHANNEL
SUPFAMiSSF63712 SSF63712, 1 hit
SSF90112 SSF90112, 1 hit
TIGRFAMsiTIGR00860 LIC, 1 hit
PROSITEiView protein in PROSITE
PS00236 NEUROTR_ION_CHANNEL, 1 hit

Sequencei

Sequence statusi: Complete.

Q99JC9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPWIRLFSGS GISFRIMAHV RHFRTLLSGF YFWEAALLLS LVATKETNSA
60 70 80 90 100
RSRSAPMSPS DFLDKLMGRT SGYDARIRPN FKGPPVNVTC NIFINSFGSI
110 120 130 140 150
AETTMDYRVN IFLRQKWNDP RLAYSEYPDD SLDLDPSMLD SIWKPDLFFA
160 170 180 190 200
NEKGANFHEV TTDNKLLRIF KNGNVLYSIR LTLTLSCPMD LKNFPMDVQT
210 220 230 240 250
CIMQLESFGY TMNDLIFEWQ DEAPVQVAEG LTLPQFLLKE EKDLRYCTKH
260 270 280 290 300
YNTGKFTCIE VRFHLERQMG YYLIQMYIPS LLIVILSWVS FWINMDAAPA
310 320 330 340 350
RVALGITTVL TMTTQSSGSR ASLPKVSYVK AIDIWMAVCL LFVFSALLEY
360 370 380 390 400
AAVNFVSRQH KELLRFRRKR KNKTEAFALE KFYRFSDTDD EVRESRFSFT
410 420 430 440 450
AYGMGPCLQA KDGVVPKGPN HAVQVMPKSA DEMRKVFIDR AKKIDTISRA
460 470 480
CFPLAFLIFN IFYWVIYKIL RHEDIHHQQD
Length:480
Mass (Da):55,555
Last modified:June 1, 2001 - v1
Checksum:i322478D9A3052299
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ310838 mRNA Translation: CAC35982.1
RefSeqiNP_446176.3, NM_053724.3
UniGeneiRn.10038

Genome annotation databases

GeneIDi114516
KEGGirno:114516

Similar proteinsi

Entry informationi

Entry nameiQ99JC9_RAT
AccessioniPrimary (citable) accession number: Q99JC9
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: February 28, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)