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Protein

Immediate early response gene 5-like protein

Gene

Ier5l

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Immediate early response gene 5-like protein
Gene namesi
Name:Ier5l
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1919750. Ier5l.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 406406Immediate early response gene 5-like proteinPRO_0000334657Add
BLAST

Proteomic databases

PaxDbiQ99J55.
PRIDEiQ99J55.

PTM databases

PhosphoSiteiQ99J55.

Expressioni

Gene expression databases

BgeeiQ99J55.
GenevisibleiQ99J55. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000132594.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi59 – 13072Gln-richAdd
BLAST
Compositional biasi167 – 23266Pro-richAdd
BLAST

Sequence similaritiesi

Belongs to the IER family.Curated

Phylogenomic databases

eggNOGiENOG410J77W. Eukaryota.
ENOG410YHIY. LUCA.
GeneTreeiENSGT00730000111126.
HOGENOMiHOG000112999.
HOVERGENiHBG107988.
InParanoidiQ99J55.
OMAiARFEDFC.
OrthoDBiEOG7XH6R3.
PhylomeDBiQ99J55.
TreeFamiTF331376.

Family and domain databases

InterProiIPR008653. IER.
[Graphical view]
PANTHERiPTHR15895. PTHR15895. 2 hits.
PfamiPF05760. IER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q99J55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MECALDAQSL ISISLRKIHS SRTQRGGIKL HKNLLVSYVL RNARQLYLSE
60 70 80 90 100
RYAELYRRQQ QQQQQQPPHH QHQHLAYAAP GMPASAADFG PLQLGGGGDA
110 120 130 140 150
EAREPVARHQ LHQLHQLHQL HLQQQLHQHQ HPAPRGCTAA APVAVAGAPA
160 170 180 190 200
GCAGALSELP GCAALQPPHG APHRGQHLEP LQPGPAPLPP PAPAALCPRD
210 220 230 240 250
PRVPAACSAP SVLPGAAPST VAASSPPAST APSSSTGFYR GAYPAPSDFG
260 270 280 290 300
VHCSSQTTVL DLDTHVVTTV ENGYLHQDCC ASAHCPCCGQ GAPGPGLASA
310 320 330 340 350
AGCKRKYYPG QEEEDDEEDA GDLGAEPPGG TPFAPCKRAR FEDFCPDSSP
360 370 380 390 400
DASNISNLIS IFGSGFSGLV SRQPDSSEQP PPLNGQLCAK QALASLGAWT

RAIVAF
Length:406
Mass (Da):42,530
Last modified:June 1, 2001 - v1
Checksum:i0A0A6722F7923DC5
GO

Sequence cautioni

The sequence BAC25357.1 differs from that shown. Reason: Frameshift at positions 142, 153, 160, 168, 216 and 298. Curated
The sequence BAC28563.1 differs from that shown. Reason: Frameshift at position 405. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti160 – 1612PG → RR in BAC25357 (PubMed:16141072).Curated
Sequence conflicti279 – 2791C → L in BAC25357 (PubMed:16141072).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012145 mRNA. Translation: BAC25357.1. Frameshift.
AK034055 mRNA. Translation: BAC28563.1. Frameshift.
AL954299 Genomic DNA. Translation: CAM23296.1.
BC003464 mRNA. Translation: AAH03464.1.
BC010234 mRNA. Translation: AAH10234.1.
BC040084 mRNA. Translation: AAH40084.1.
CCDSiCCDS38095.1.
RefSeqiNP_084520.3. NM_030244.3.
UniGeneiMm.295464.

Genome annotation databases

EnsembliENSMUST00000065134; ENSMUSP00000132594; ENSMUSG00000089762.
GeneIDi72500.
KEGGimmu:72500.
UCSCiuc008jco.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012145 mRNA. Translation: BAC25357.1. Frameshift.
AK034055 mRNA. Translation: BAC28563.1. Frameshift.
AL954299 Genomic DNA. Translation: CAM23296.1.
BC003464 mRNA. Translation: AAH03464.1.
BC010234 mRNA. Translation: AAH10234.1.
BC040084 mRNA. Translation: AAH40084.1.
CCDSiCCDS38095.1.
RefSeqiNP_084520.3. NM_030244.3.
UniGeneiMm.295464.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000132594.

PTM databases

PhosphoSiteiQ99J55.

Proteomic databases

PaxDbiQ99J55.
PRIDEiQ99J55.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000065134; ENSMUSP00000132594; ENSMUSG00000089762.
GeneIDi72500.
KEGGimmu:72500.
UCSCiuc008jco.1. mouse.

Organism-specific databases

CTDi389792.
MGIiMGI:1919750. Ier5l.

Phylogenomic databases

eggNOGiENOG410J77W. Eukaryota.
ENOG410YHIY. LUCA.
GeneTreeiENSGT00730000111126.
HOGENOMiHOG000112999.
HOVERGENiHBG107988.
InParanoidiQ99J55.
OMAiARFEDFC.
OrthoDBiEOG7XH6R3.
PhylomeDBiQ99J55.
TreeFamiTF331376.

Miscellaneous databases

ChiTaRSiIer5l. mouse.
NextBioi336342.
PROiQ99J55.
SOURCEiSearch...

Gene expression databases

BgeeiQ99J55.
GenevisibleiQ99J55. MM.

Family and domain databases

InterProiIPR008653. IER.
[Graphical view]
PANTHERiPTHR15895. PTHR15895. 2 hits.
PfamiPF05760. IER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Diencephalon.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: 129 and FVB/N.
    Tissue: Mammary tumor.

Entry informationi

Entry nameiIER5L_MOUSE
AccessioniPrimary (citable) accession number: Q99J55
Secondary accession number(s): Q8BTA0, Q8CC26
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: June 1, 2001
Last modified: November 11, 2015
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.