Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Pol polyprotein

Gene

pol

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionNucleotidyltransferase, RNA-directed DNA polymeraseSAAS annotation, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Pol polyproteinImported
Gene namesi
Name:polImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Structurei

3D structure databases

ProteinModelPortaliQ99B11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 236Reverse transcriptaseInterPro annotationAdd BLAST193
Domaini436 – 559RNase HInterPro annotationAdd BLAST124

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiView protein in InterPro
IPR012337. RNaseH-like_sf.
IPR002156. RNaseH_domain.
IPR036397. RNaseH_sf.
IPR000477. RT_dom.
IPR010659. RVT_connect.
IPR010661. RVT_thumb.
PfamiView protein in Pfam
PF00075. RNase_H. 1 hit.
PF00078. RVT_1. 1 hit.
PF06815. RVT_connect. 1 hit.
PF06817. RVT_thumb. 1 hit.
SUPFAMiSSF53098. SSF53098. 1 hit.
PROSITEiView protein in PROSITE
PS50879. RNASE_H. 1 hit.
PS50878. RT_POL. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q99B11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PISPIEPVPV KLKPGMDGPK VKQWPLTEEK IKALVEICTE MEKEGKISKI
60 70 80 90 100
GPENPYNTPV FAIKKKSSSS GTWRELVDFR ELNKRTQDFW EVQLGIPHPA
110 120 130 140 150
GLKKKKSVTV LDVGDAYFSV PLDKDFRKYT AFTIPSTNNE TPGIRYQYNV
160 170 180 190 200
LPQGWKGSPA IFQCSMTKIL EPFRKQNPDI VIYQYMDDLY VGSDLEIEQH
210 220 230 240 250
RIKIEKLREH LLKWGFYTPD KKHQKEPPFL WMGYELHPDK WTVQPIQLPE
260 270 280 290 300
KDSWTVNDLQ KLVGKLNWAS QIYAGIKVRQ LCKLLRGAKS LTEVVQLTEE
310 320 330 340 350
AELELAENRE ILKEPVHGVY YDPSKDLIAE LQKQGQGQWT YQIYQEPFKN
360 370 380 390 400
LKTGKYARMK GAHTNDVKPV TEAVQKIARE SIVIWGKTPK FKLPIQKETW
410 420 430 440 450
EAWWTEYWQA TWIPEWEFVN TPPLVKLWYQ LETEPIVGAE TFYVDGAANR
460 470 480 490 500
ETKLGKAGYV TDKGRQKVVS ITDTTNQKTE LQAIHLALQD SGLEVNIVTD
510 520 530 540 550
SQYALGIIQA QPDQSESELV SQIIEQLIKK EKVYLAWVPA HKGIGGNEQV
560
DKLVSAGIRK VL
Length:562
Mass (Da):64,513
Last modified:June 1, 2001 - v1
Checksum:i025E75640DB3972E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei562Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF331343 Genomic RNA. Translation: AAK12218.1.

Similar proteinsi

Entry informationi

Entry nameiQ99B11_9HIV1
AccessioniPrimary (citable) accession number: Q99B11
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: October 25, 2017
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)