B-cell specific latent nuclear protein

Functionⁱ

GO - Molecular functionⁱ

regulatory region DNA binding Source: InterPro
transcription factor activity, sequence-specific DNA binding Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: B-cell specific latent nuclear proteinImported
Organismⁱ	Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus)Imported
Taxonomic identifierⁱ	37296 [NCBI]
Taxonomic lineageⁱ	Viruses › dsDNA viruses, no RNA stage › Herpesvirales › Herpesviridae › Gammaherpesvirinae › Rhadinovirus
Virus hostⁱ	Homo sapiens (Human) [TaxID: 9606]

Subcellular locationⁱ

GO - Cellular componentⁱ

host cell nucleus Source: UniProtKB-KW

Complete GO annotation...

Keywords - Cellular componentⁱ

NucleusImported

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q99AM3.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	6 – 111	IRF tryptophan pentad repeat DNA-bindingInterPro annotationAdd BLAST		106

Family and domain databases

Gene3Dⁱ	2.60.200.10. 1 hit.
InterProⁱ	View protein in InterPro IPR001346. Interferon_reg_fact_DNA-bd_dom. IPR019471. Interferon_reg_factor-3. IPR017855. SMAD_dom-like. IPR008984. SMAD_FHA_domain.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF10401. IRF-3. 1 hit.
SUPFAMⁱ	SSF49879. SSF49879. 1 hit.
PROSITEⁱ	View protein in PROSITE PS51507. IRF_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q99AM3-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAGRRLTWIS EFIVGALDSD KYPLVKWLDR STGTFLAPAA RNDVIPLDSL 
        60         70         80         90        100
QFFIDFKREC LSKGLHPRDL LGSPITAFGK ICTTSRRLRR LPGEEYEVVQ 
       110        120        130        140        150
GINCRRWRLL CAEVKECWWC VHARTHLHSG SSLWEILYQH SVRLEKHRRR 
       160        170        180        190        200
PRRPFVGENS DSSEEDHPAF CDVPVTQTGA ESEDSGDEGP STRHSASGVQ 
       210        220        230        240        250
PVDDANADSP GSGDEGPSTR HSDSQPPPAD ETTVHTDNVE DDLTLLDKES 
       260        270        280        290        300
ACALMYHVGQ EMDMLMRAMC DEDLFDLLGI PEDVIATSQP GGDTDASGVV 
       310        320        330        340        350
TEGSIAASAV GAGVEDVYLA GALEAQNVAG EYVLEISDEE VDDGAGLPPA 
       360        370        380        390        400
SRRRPVVGEF LWDDGPRRHE RPTTRRIRHR KLRSAYYRVA RPPVMITDRL 
       410        420        430        440        450
GVEVFYFGRP AMSLEVERKV FILCSQNPLA DISHSCLHSR KGLRVLLPKP 
       460        470        480        490        500
DDNNTGPGDV NLLAAVLRSF ASGLVIVSLR SGIYVKNLCK STVLYHGNNP 
       510        520        530        540        550
PKKFGVICGL SSRAVLDVFN VAQYRIQGHE HIKKTTVFIG GDPTSAEQFD 
       560 
MVPLVIKLRL RSVTCDD

Length:567

Mass (Da):62,664

Last modified:June 1, 2001 - v1

Checksum:ⁱ7AF404225638D3DC

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY008303 mRNA. Translation: AAG50357.1.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AY008303 mRNA. Translation: AAG50357.1.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY008303 mRNA. Translation: AAG50357.1.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AY008303 mRNA. Translation: AAG50357.1.

3D structure databases

ProteinModelPortalⁱ	Q99AM3.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Family and domain databases

Gene3Dⁱ	2.60.200.10. 1 hit.
InterProⁱ	View protein in InterPro IPR001346. Interferon_reg_fact_DNA-bd_dom. IPR019471. Interferon_reg_factor-3. IPR017855. SMAD_dom-like. IPR008984. SMAD_FHA_domain.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF10401. IRF-3. 1 hit.
SUPFAMⁱ	SSF49879. SSF49879. 1 hit.
PROSITEⁱ	View protein in PROSITE PS51507. IRF_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q99AM3_HHV8
Accessionⁱ	Q99AM3Primary (citable) accession number: Q99AM3
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	June 1, 2001
	Last sequence update:	June 1, 2001
	Last modified:	November 30, 2016
	This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB - Q99AM3 (Q99AM3_HHV8)

Your basket is currently empty.

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Family and domain databases

Sequenceⁱ

Sequence databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q99AM3 (Q99AM3_HHV8)

Your basket is currently empty.

B-cell specific latent nuclear protein

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ