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Protein
Submitted name:

Dopamine D4 receptor

Gene

dopamine D4 receptor

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Dopamine D4 receptorImported
Gene namesi
Name:dopamine D4 receptorImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei34 – 53HelicalSequence analysisAdd BLAST20
Transmembranei65 – 86HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ99587.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 88G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST45

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR002185. Dopamine_D4_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PANTHERiPTHR24249:SF337. PTHR24249:SF337. 1 hit.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiView protein in PROSITE
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q99587-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNRSTADAD GLLAGRGPAA GASAGASAGL AGQGALLIGA VLAGNSLVCV
60 70 80
SVATERALQT PTNSFIVSLA AADLLLALLV LPLFVYSE
Length:88
Mass (Da):8,482
Last modified:May 1, 1997 - v1
Checksum:i314093AB4678CEDF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S82918 Genomic DNA. Translation: AAB46803.1.
UniGeneiHs.99922.

Similar proteinsi

Entry informationi

Entry nameiQ99587_HUMAN
AccessioniPrimary (citable) accession number: Q99587
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: August 30, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.