Q99587 (Q99587_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dopamine D4 receptor EMBL AAB46803.1

Gene names

Name:

dopamine D4 receptor EMBL AAB46803.1

Organism

Homo sapiens (Human) EMBL AAB46803.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	88 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Receptor EMBL AAB46803.1
Gene Ontology (GO)
Biological_process	adenylate cyclase-inhibiting dopamine receptor signaling pathway Inferred from electronic annotation. Source: Compara adult locomotory behavior Inferred from electronic annotation. Source: Compara behavioral fear response Inferred from electronic annotation. Source: Compara behavioral response to cocaine Inferred from electronic annotation. Source: Compara olfactory learning Inferred from electronic annotation. Source: Compara regulation of calcium-mediated signaling Inferred from electronic annotation. Source: Compara regulation of dopamine metabolic process Inferred from electronic annotation. Source: Compara regulation of inhibitory postsynaptic membrane potential Inferred from electronic annotation. Source: Compara regulation of neurotransmitter secretion Inferred from electronic annotation. Source: Compara response to amphetamine Inferred from electronic annotation. Source: Compara short-term memory Inferred from electronic annotation. Source: Compara synaptic transmission, dopaminergic Inferred from electronic annotation. Source: Compara
Cellular_component	cell cortex Inferred from electronic annotation. Source: Compara dendritic spine Inferred from electronic annotation. Source: Compara integral to membrane Inferred from electronic annotation. Source: InterPro neuronal cell body Inferred from electronic annotation. Source: Compara plasma membrane Inferred from electronic annotation. Source: Compara terminal bouton Inferred from electronic annotation. Source: Compara vesicle membrane Inferred from electronic annotation. Source: Compara
Molecular_function	dopamine neurotransmitter receptor activity, coupled via Gi/Go Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAB46803.1

Sequences

	Sequence		Length	Mass (Da)
	Q99587 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: 314093AB4678CEDF	FASTA	88	8,482
	10 20 30 40 50 60 MGNRSTADAD GLLAGRGPAA GASAGASAGL AGQGALLIGA VLAGNSLVCV SVATERALQT 70 80 PTNSFIVSLA AADLLLALLV LPLFVYSE

References

[1]	"Identification of two novel polymorphisms and a rare deletion variant in the human dopamine D4 receptor gene." Cichon S., Nothen M.M., Catalano M., Di Bella D., Maier W., Lichtermann D., Minges J., Albus M., Borrmann M., Franzek E. Psychiatr. Genet. 5:97-103(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	S82918 Genomic DNA. Translation: AAB46803.1.
IPI	IPI00011225.
UniGene	Hs.99922.
3D structure databases
ProteinModelPortal	Q99587.
ModBase	Search...
Protein-protein interaction databases
STRING	Q99587.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	Q99587.
Bgee	Q99587.
Family and domain databases
InterPro	IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. [Graphical view]
Pfam	PF00001. 7tm_1. 1 hit. [Graphical view]
PRINTS	PR00237. GPCRRHODOPSN.
PROSITE	PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q99587_HUMAN

Accession

Primary (citable) accession number: Q99587

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1997
Last sequence update:	May 1, 1997
Last modified:	April 3, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.