ID NSP6_ROTHW Reviewed; 92 AA. AC Q993T1; DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot. DT 01-JUN-2001, sequence version 1. DT 08-NOV-2023, entry version 50. DE RecName: Full=Non-structural protein 6 {ECO:0000255|HAMAP-Rule:MF_04093}; DE Short=NSP6 {ECO:0000255|HAMAP-Rule:MF_04093}; OS Rotavirus A (strain RVA/Human/United States/Wa/1974/G1P1A[8]) (RV-A). OC Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes; OC Reovirales; Sedoreoviridae; Rotavirus; Rotavirus A. OX NCBI_TaxID=10962; OH NCBI_TaxID=9606; Homo sapiens (Human). RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC RNA]. RX PubMed=11778700; DOI=10.1023/a:1012577407824; RA Mohan K.V.K., Atreya C.D.; RT "Nucleotide sequence analysis of rotavirus gene 11 from two tissue culture- RT adapted ATCC strains, RRV and Wa."; RL Virus Genes 23:321-329(2001). CC -!- SUBUNIT: Interacts with NSP2 and NSP5. {ECO:0000255|HAMAP- CC Rule:MF_04093}. CC -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04093}. CC Host mitochondrion {ECO:0000255|HAMAP-Rule:MF_04093}. Note=Found in CC spherical cytoplasmic structures, called viral factories, that appear CC early after infection and are the site of viral replication and CC packaging. {ECO:0000255|HAMAP-Rule:MF_04093}. CC -!- SIMILARITY: Belongs to the rotavirus A NSP6 family. {ECO:0000255|HAMAP- CC Rule:MF_04093}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF306494; AAK15270.1; -; Genomic_RNA. DR Proteomes; UP000006581; Genome. DR GO; GO:0033650; C:host cell mitochondrion; IEA:UniProtKB-SubCell. DR HAMAP; MF_04093; ROTA_NSP6; 1. DR InterPro; IPR006950; Rotavirus_NSP6. DR Pfam; PF04866; Rota_NS6; 1. PE 3: Inferred from homology; KW Host cytoplasm; Host mitochondrion. FT CHAIN 1..92 FT /note="Non-structural protein 6" FT /id="PRO_0000369525" SQ SEQUENCE 92 AA; 10909 MW; EEB2FBF272BCE7BF CRC64; MNRLLQRQLF LENLLVGTNS MFHQISKHSI NTCCRSLQRI LDHLILLQTI HSPVFRLDRM QLRQMQMLAC LWIHQHNHDL QATLGAIKWI SP //