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Protein

Non-structural protein 6

Gene
N/A
Organism
Rotavirus A (strain Human/United States/Wa/1974 G1-P1A[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1) (RV-A)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein 6
Short name:
NSP6
OrganismiRotavirus A (strain Human/United States/Wa/1974 G1-P1A[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1) (RV-A)
Taxonomic identifieri10962 [NCBI]
Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirusRotavirus A
Virus hostiHomo sapiens (Human) [TaxID: 9606]
ProteomesiUP000006581: Genome

Subcellular locationi

Host cytoplasm
Note: Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.By similarity

GO - Cellular componenti

  1. host cell cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Host cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 9292Non-structural protein 6PRO_0000369525Add
BLAST

Interactioni

Subunit structurei

Interacts with NSP5.By similarity

Family & Domainsi

Sequence similaritiesi

Belongs to the rotavirus A NSP6 family.Curated

Family and domain databases

InterProiIPR006950. Rotavirus_NSP6.
[Graphical view]
PfamiPF04866. Rota_NS6. 1 hit.
[Graphical view]
ProDomiPD008065. Rota_NS6. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Q993T1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNRLLQRQLF LENLLVGTNS MFHQISKHSI NTCCRSLQRI LDHLILLQTI
60 70 80 90
HSPVFRLDRM QLRQMQMLAC LWIHQHNHDL QATLGAIKWI SP
Length:92
Mass (Da):10,909
Last modified:June 1, 2001 - v1
Checksum:iEEB2FBF272BCE7BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF306494 Genomic RNA. Translation: AAK15270.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF306494 Genomic RNA. Translation: AAK15270.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR006950. Rotavirus_NSP6.
[Graphical view]
PfamiPF04866. Rota_NS6. 1 hit.
[Graphical view]
ProDomiPD008065. Rota_NS6. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Publicationsi

  1. "Nucleotide sequence analysis of rotavirus gene 11 from two tissue culture-adapted ATCC strains, RRV and Wa."
    Mohan K.V.K., Atreya C.D.
    Virus Genes 23:321-329(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiNSP6_ROTHW
AccessioniPrimary (citable) accession number: Q993T1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 1, 2001
Last modified: January 7, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.