Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Envelope glycoprotein gp160

Gene

env

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processApoptosisSAAS annotation, Fusion of virus membrane with host membraneSAAS annotation, Host-virus interaction, Viral attachment to host cellSAAS annotation, Viral penetration into host cytoplasm, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Envelope glycoprotein gp160SAAS annotation
Gene namesi
Name:envImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

  • Host endosome membrane SAAS annotation; Single-pass type I membrane protein SAAS annotation
  • Virion membrane SAAS annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei458 – 479HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Keywords - Cellular componenti

Host endosomeSAAS annotation, Membrane, Viral envelope proteinImported, Virion

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ993B2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 457GP120InterPro annotationAdd BLAST449
Domaini476 – 618GP41InterPro annotationAdd BLAST143

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

CDDicd09909. HIV-1-like_HR1-HR2. 1 hit.
Gene3Di2.170.40.20. 2 hits.
InterProiView protein in InterPro
IPR036377. Gp120_core_sf.
IPR000328. GP41-like.
IPR000777. HIV1_Gp120.
PfamiView protein in Pfam
PF00516. GP120. 1 hit.
PF00517. GP41. 1 hit.
SUPFAMiSSF56502. SSF56502. 3 hits.

Sequencei

Sequence statusi: Fragment.

Q993B2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ASDAKAYDTE VHNVWATHAC VPTDPNPQEV VLVNVTENFN MWKNDMVEQM
60 70 80 90 100
HEDIISLWDQ SLKPCVKLTP LCVSLKCTDL KNDTNTNSSS GRMIMEKGEI
110 120 130 140 150
KNCSFNISTS KRGKVQKEYA FFYKLDIIPI DNDTTSYTLT SCNTSVITQA
160 170 180 190 200
CPKVSFEPIP IHYCAPAGFA ILKCNNKTFN GTGPCTNVST VQCTHGIRPV
210 220 230 240 250
VSTQLLLNGS LAEEEVVIRS ANFTDNAKTI IVQLNTSVEI NCTRPNNNTR
260 270 280 290 300
KKIRIQRGPG RTFDTIGKIG NMRQAHCNIS RAKWNATLKQ IDSKLREQFG
310 320 330 340 350
NNKTIIFKQS SGGDPEIVTH SFNCGGEFFY CNSTQLFNST WFNSTWSTEG
360 370 380 390 400
SNNTEGSDTI TLPCRIKQII NMWQEVGKAM YAPPISGQIR CSSNITGLLL
410 420 430 440 450
TRDGGNSNNE SEIFRPGGGD MRDNWRSELY KYKVVKIEPL GVAPTKAKRR
460 470 480 490 500
VVQREKRAVG IGALFLGFLG AAGSTMGAAS MTLTVQARQL LSGIVQQQNN
510 520 530 540 550
LLRAIEAQQH LLQLTVWGIK QLQARILAVE RYLKDQQLLG IWGCSGKLIC
560 570 580 590 600
TTAVPWNASW SNKSLEQIWN NMTWMEWDRE INNYTSLIHS LIEESQNQQE
610
KNEQELLELD KWASLWNW
Length:618
Mass (Da):69,364
Last modified:June 1, 2001 - v1
Checksum:iB9C791E7D357D2AE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei618Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF321143 Genomic DNA. Translation: AAK20291.1.
PIRiA53591.

Similar proteinsi

Entry informationi

Entry nameiQ993B2_9HIV1
AccessioniPrimary (citable) accession number: Q993B2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: October 25, 2017
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)