Q99373 (PET20_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein PET20, mitochondrial

Alternative name(s):
Petite colonies protein 20

Gene names

Name:	PET20
Ordered Locus Names:	YPL159C
ORF Names:	P2567

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	253 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Required for respiratory growth, stability of the mitochondrial genome and for proper assembly or maintenance of mitochondrial proteins. Ref.4
Subcellular location	Mitochondrion Ref.4.

Ontologies

Keywords
Cellular component	Mitochondrion
Domain	Transit peptide
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	aerobic respiration Inferred from mutant phenotype Ref.4. Source: SGD
Cellular component	mitochondrion Inferred from direct assay Ref.4. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 36	36	Mitochondrion Potential
	Chain	37 – 253	217	Protein PET20, mitochondrial		PRO_0000240390

Sequences

	Sequence		Length	Mass (Da)
	Q99373 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: E57F275011F2A50D	FASTA	253	29,103
	10 20 30 40 50 60 MLKLARPFIP PLSRNNAISS GIVLTSRRFQ SSFTFLSNQS LLSKNQMKSK RKKGSKKAAY 70 80 90 100 110 120 HRQPPEHEHT APLIKQNKTI TKKEHSDVRG SHLKKKRSDF SWLPRVPSTS HLKQSDMTTN 130 140 150 160 170 180 VLYSGYRPLF INPNDPKLKE DTGSTLYEFA MKLEDLNEPL SPWISSATGL EFFSEWENIP 190 200 210 220 230 240 SELLKNLKPF HPPKEKSMNT NELIHVSAKR NTLVDNKTSE TLQRKMDEFS KRRGKGRKKS 250 VVTLLQMKKK LEG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The sequence of 55 kb on the left arm of yeast chromosome XVI identifies a small nuclear RNA, a new putative protein kinase and two new putative regulators." Purnelle B., Coster F., Goffeau A. Yeast 12:1483-1492(1996) [PubMed: 8948103] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI." Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M. , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J. Nature 387:103-105(1997) [PubMed: 9169875] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[4]	"Phenotypes of yeast mutants lacking the mitochondrial protein Pet20p." Polevoda B., Panciera Y., Brown S.P., Wei J., Sherman F. Yeast 23:127-139(2006) [PubMed: 16491469] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X96770 Genomic DNA. Translation: CAA65562.1. Z73515 Genomic DNA. Translation: CAA97864.1. BK006949 Genomic DNA. Translation: DAA11275.1.
PIR	S65170.
RefSeq	NP_015166.1. NM_001183973.1.
3D structure databases
ProteinModelPortal	Q99373.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-3991N.
IntAct	Q99373. 2 interactions.
MINT	MINT-521572.
STRING	Q99373.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YPL159C; YPL159C; YPL159C.
GeneID	855944.
KEGG	sce:YPL159C.
NMPDR	fig|4932.3.peg.6295.
Organism-specific databases
CYGD	YPL159c.
SGD	S000006080. PET20.
Phylogenomic databases
eggNOG	fuNOG12015.
GeneTree	EFGT00050000008672.
OMA	EFAMKLE.
OrthoDB	EOG4RV624.
Gene expression databases
ArrayExpress	Q99373.
Genevestigator	Q99373.
GermOnline	YPL159C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR014804. Pet20. [Graphical view]
Pfam	PF08692. Pet20. 2 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	980711.

Entry information

Entry name

PET20_YEAST

Accession

Primary (citable) accession number: Q99373
Secondary accession number(s): D6W3K9

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program