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Q992J0 (RDRP_BOOLV) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
RNA-directed RNA polymerase

Short name=RdRp
EC=2.7.7.48
Alternative name(s):
RNA replicase
Short name=Protein A
OrganismBoolarra virus (BoV)
Taxonomic identifier12286 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageNodaviridaeAlphanodavirus
Virus hostHepialidae (ghost moths) [TaxID: 41021]

Protein attributes

Sequence length998 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

RNA-dependent RNA polymerase which replicates the viral genome composed of 2 RNA segments, RNA1 AND RNA2 Potential.

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

Sequence similarities

Belongs to the nodaviridae RNA polymerase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 998998RNA-directed RNA polymerase
PRO_0000222445

Sequences

Sequence LengthMass (Da)Tools
Q992J0 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 7FAFFE4FC7329253

FASTA998111,204
        10         20         30         40         50         60 
MTIKIILGEH QITRTELLGG IVIVSGCGAV AYCISKFWGY GAIAPYPQSG GNRVTRALQR 

        70         80         90        100        110        120 
AVIDKTKTPI KTHFYPLDSL RTVTPRRASD NGHAVSGAVR DAARRLINES IETVGGSKFE 

       130        140        150        160        170        180 
LNPNPNSTMG PRNHFHFAVG DLAQNFRDDQ PAADAFIVGV DVDYYITEPD VLLEHMRPLV 

       190        200        210        220        230        240 
LHTFNPKKVS GFDADSPFTI NNNLVEYKVS GGAAWVHPVW DWCEAGEFIA SRVRSSWFEW 

       250        260        270        280        290        300 
LLQLPLRCLG LERVGYHKIH HCRPWTDCPD RALVYTIPQH TVWRFTWIDT EIHTRKLKRI 

       310        320        330        340        350        360 
TYQDNTKPGW NRLEHVSDNN QLLVSIGREG EHMQITIEKD KLEMLSGLGA TQSVNARLIG 

       370        380        390        400        410        420 
MGHKDPLYTS MIVQYYTGKK VVLSVAPTVY RPTMPRVHWP VTSDADVPEV SARQYTKPII 

       430        440        450        460        470        480 
SDCMMMPMIK RWETMSESIE RRVTFVANNK KPSDAVAKIA AEFVSLMNGP FIDLEPLTIE 

       490        500        510        520        530        540 
ETVERLNKPS QQLQLRAVFE IMGVEPRQVI ESFNKNEPGM KSSRIISAFP DILFIVKVSR 

       550        560        570        580        590        600 
YTLAYSDAVL HAEHNQHWYY PGRTPVGITD GVCEFVSDCD GQVIETDFSN LDGRVSGWMQ 

       610        620        630        640        650        660 
RNIAQKAMVQ AFRAEYRDEI ISFMDTIINC PAKAKRFGFR YEPGMGVKSG SPTTTPHNTQ 

       670        680        690        700        710        720 
YNACVEYTAL KFEYPDANPE DLFSLLGPKC GDDGLARATI QKTINRAAKC YGLELKVEKY 

       730        740        750        760        770        780 
NPEVGLCFLS RVFVDPLNTP TTIQDPLRTL RKLHITTRDP TIPIADAACD RVEGYLCTDA 

       790        800        810        820        830        840 
HTPLISEYCR MVQRLYGPKT STRDVREARR SRNKEKPYWL TCDGSWPQHP QDALLMKQIV 

       850        860        870        880        890        900 
VSRTGIDEDT VDKLIGRFAA MKDVWEPITL ESEESKAAQT IDEEGVAPGS VDESLLKLND 

       910        920        930        940        950        960 
AKQTRSNSGT SGPHTKGGGS GTGNELPRST KQRAKGPRQS AGLPKQGKAN SKPNGNVAAG 

       970        980        990 
QAQHGGIPRG KTPSGGKTNA RRAPPKAGAQ PGAPTNPK 

« Hide

References

[1]"Comparisons among the larger genome segments of six nodaviruses and their encoded RNA replicases."
Johnson K.N., Johnson K.L., Dasgupta R., Gratsch T., Ball L.A.
J. Gen. Virol. 82:1855-1866(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF329080 Genomic RNA. Translation: AAK15751.1.
RefSeqNP_689439.1. NC_004142.1.

3D structure databases

ProteinModelPortalQ992J0.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID956656.

Family and domain databases

InterProIPR020237. RNA-dir_pol_C_nodavirus.
[Graphical view]
ProDomPD029982. RNA-dir_pol_nodavirus. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameRDRP_BOOLV
AccessionPrimary (citable) accession number: Q992J0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: June 1, 2001
Last modified: April 16, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families