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Protein

Protein B2

Gene

B2

Organism
Boolarra virus (BoV)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Binds double-strand RNA (dsRNA) with high affinity. Suppresses the host RNA silencing-based antiviral response (By similarity).By similarity

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Suppressor of RNA silencing

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein B2
Gene namesi
Name:B2
OrganismiBoolarra virus (BoV)
Taxonomic identifieri12286 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageNodaviridaeAlphanodavirus
Virus hostiHepialidae (ghost moths) [TaxID: 41021]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 106106Protein B2PRO_0000223689Add
BLAST

Expressioni

Developmental stagei

Expressed at high levels early in the viral replication cycle.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ992I9.
SMRiQ992I9. Positions 1-72.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 7373RNA-bindingBy similarityAdd
BLAST

Domaini

The dsRNA-binding region is required for suppression of RNA silencing.By similarity

Sequence similaritiesi

Belongs to the nodaviridae B2 protein family.Curated

Family and domain databases

InterProiIPR024377. RNA-bd_B2.
[Graphical view]
PfamiPF11473. B2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q992I9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQSKLALIQE LPDRIQKAVE VVLAMSYQEA PNNVRRDLDN LQACLNKAKQ
60 70 80 90 100
TVNRMVTSLL DKPSMAAYLE GKPLPEERPT LEERLRKLEL SREPPPTRSD

PAPAKL
Length:106
Mass (Da):12,004
Last modified:June 1, 2001 - v1
Checksum:i94E05B689304BCA4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF329080 Genomic RNA. Translation: AAK15752.1.
RefSeqiNP_689440.1. NC_004142.1.

Genome annotation databases

GeneIDi956657.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF329080 Genomic RNA. Translation: AAK15752.1.
RefSeqiNP_689440.1. NC_004142.1.

3D structure databases

ProteinModelPortaliQ992I9.
SMRiQ992I9. Positions 1-72.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi956657.

Family and domain databases

InterProiIPR024377. RNA-bd_B2.
[Graphical view]
PfamiPF11473. B2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Dasgupta R., Ye B., Harper T.A.
    Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiB2_BOOLV
AccessioniPrimary (citable) accession number: Q992I9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: June 1, 2001
Last modified: October 1, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Miscellaneous

Encoded on a subgenomic RNA (RNA3) synthesized during replication and which is co-terminal with RNA1.

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.