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Q992I9 (B2_BOOLV) Reviewed, UniProtKB/Swiss-Prot

Last modified October 19, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein B2
Gene names
Name:B2
OrganismBoolarra virus (BoV)
Taxonomic identifier12286 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageNodaviridaeAlphanodavirus
Virus hostHepialidae (ghost moths) [TaxID: 41021]

Protein attributes

Sequence length106 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Binds double-strand RNA (dsRNA) with high affinity. Suppresses the host RNA silencing-based antiviral response By similarity.

Subunit structure

Homodimer By similarity.

Developmental stage

Expressed at high levels early in the viral replication cycle.

Domain

The dsRNA-binding region is required for suppression of RNA silencing By similarity.

Miscellaneous

Encoded on a subgenomic RNA (RNA3) synthesized during replication and which is co-terminal with RNA1.

Sequence similarities

Belongs to the nodaviridae B2 protein family.

Ontologies

Keywords
   LigandRNA-binding
   Molecular functionSuppressor of RNA silencing
Gene Ontology (GO)
   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 106106Protein B2
PRO_0000223689

Regions

Region1 – 7373RNA-binding By similarity

Sequences

Sequence LengthMass (Da)Tools
Q992I9 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 94E05B689304BCA4

FASTA10612,004
        10         20         30         40         50         60 
MQSKLALIQE LPDRIQKAVE VVLAMSYQEA PNNVRRDLDN LQACLNKAKQ TVNRMVTSLL 

        70         80         90        100 
DKPSMAAYLE GKPLPEERPT LEERLRKLEL SREPPPTRSD PAPAKL 

« Hide

References

[1]Dasgupta R., Ye B., Harper T.A.
Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF329080 Genomic RNA. Translation: AAK15752.1.
RefSeqNP_689440.1. NC_004142.1.

3D structure databases

ProteinModelPortalQ992I9.
SMRQ992I9. Positions 1-72.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID956657.

Family and domain databases

InterProIPR024377. RNA-bd_B2.
[Graphical view]
PfamPF11473. B2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB2_BOOLV
AccessionPrimary (citable) accession number: Q992I9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: June 1, 2001
Last modified: October 19, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families