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Q99125 (CWLX_BACLI) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable N-acetylmuramoyl-L-alanine amidase

EC=3.5.1.28
Alternative name(s):
Autolysin
Cell wall hydrolase
ORFL3
OrganismBacillus licheniformis
Taxonomic identifier1402 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length354 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.

Subcellular location

Secreted Potential.

Sequence similarities

Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

Ontologies

Keywords
   Biological processCell wall biogenesis/degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionHydrolase
Gene Ontology (GO)
   Biological_processpeptidoglycan catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionN-acetylmuramoyl-L-alanine amidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3939 By similarity
Chain40 – 354315Probable N-acetylmuramoyl-L-alanine amidase
PRO_0000006456

Sequences

Sequence LengthMass (Da)Tools
Q99125 [UniParc].

Last modified June 1, 1994. Version 1.
Checksum: 9A84D197B73B52CD

FASTA35438,347
        10         20         30         40         50         60 
MVKVINNFVK VNQYDRPGLK LAAVKGIVMH WTATPGASAL NERNYFNGTC IADKRYASAH 

        70         80         90        100        110        120 
YFVDRHEAQH IIPDHEVAYH AHDQNRCYVS FLKPNANTTA LGVEMCVEKD GTIHEETIRN 

       130        140        150        160        170        180 
AAELVADLCK TYGLSADRIV RHYDVTNKGC PTPWVRDAGQ LSAFRKRVDS LLGRKTVSVS 

       190        200        210        220        230        240 
AASTSQTSSS SGIILKKGMS GSHVKKLQTR LVAAGFSLPK YGADGSYGDE TVHAVVSLQK 

       250        260        270        280        290        300 
KAGIKADGIY GPSTEKALSA AEASAAGKSK TWTLPDGIYK VKNPLMKGTA VTQIQTALAA 

       310        320        330        340        350 
LYYYPDKGAK NNGIDGYYGM KTANAVKRFQ LMYGLGADGI YGPKTKAKML SLLK 

« Hide

References

[1]"Identification of four unique clones encoding 10 kDa proteins from Bacillus that cause phenotypic complementation of a phoA mutant strain of Escherichia coli."
Lee J.W.K., Edwards C.W., Hulett F.M.
J. Gen. Microbiol. 137:667-677(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: MC14.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M63942 Genomic DNA. Translation: AAA22888.1.
PIRD49754.

3D structure databases

ProteinModelPortalQ99125.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.101.10. 2 hits.
3.40.80.10. 1 hit.
InterProIPR002502. Amidase_domain.
IPR002477. Peptidoglycan-bd-like.
[Graphical view]
PfamPF01510. Amidase_2. 1 hit.
PF01471. PG_binding_1. 2 hits.
[Graphical view]
SMARTSM00644. Ami_2. 1 hit.
[Graphical view]
SUPFAMSSF47090. SSF47090. 2 hits.
SSF55846. SSF55846. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCWLX_BACLI
AccessionPrimary (citable) accession number: Q99125
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: June 1, 1994
Last modified: October 16, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families