ID   MUC4_HUMAN              Reviewed;        5412 AA.
AC   Q99102; O95938; Q9GZM2; Q9GZV6; Q9H481; Q9H482; Q9H483; Q9H484; Q9H485;
AC   Q9H486; Q9H487; Q9H4D6; Q9H4D8; Q9NPJ0; Q9NY09; Q9NY75; Q9NY76; Q9NY77;
AC   Q9NY78; Q9NY79; Q9NY80; Q9NY81;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   29-SEP-2021, sequence version 5.
DT   27-MAR-2024, entry version 177.
DE   RecName: Full=Mucin-4;
DE            Short=MUC-4;
DE   AltName: Full=Ascites sialoglycoprotein;
DE            Short=ASGP;
DE   AltName: Full=Pancreatic adenocarcinoma mucin;
DE   AltName: Full=Testis mucin;
DE   AltName: Full=Tracheobronchial mucin;
DE   Contains:
DE     RecName: Full=Mucin-4 alpha chain;
DE     AltName: Full=Ascites sialoglycoprotein 1;
DE              Short=ASGP-1;
DE   Contains:
DE     RecName: Full=Mucin-4 beta chain;
DE     AltName: Full=Ascites sialoglycoprotein 2;
DE              Short=ASGP-2;
DE   Flags: Precursor;
GN   Name=MUC4;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 12 AND 13), PARTIAL NUCLEOTIDE
RP   SEQUENCE [MRNA] (ISOFORMS 2; 3; 11; 15; 16 AND 17), SUBCELLULAR LOCATION,
RP   TOPOLOGY, TISSUE SPECIFICITY, AND VARIANT ASP-4324.
RC   TISSUE=Lung, and Testis;
RX   PubMed=10880978; DOI=10.1046/j.1432-1327.2000.01504.x;
RA   Moniaux N., Escande F., Batra S.K., Porchet N., Laine A., Aubert J.-P.;
RT   "Alternative splicing generates a family of putative secreted and membrane-
RT   associated MUC4 mucins.";
RL   Eur. J. Biochem. 267:4536-4544(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3; 5; 7; 8; 9; 10 AND 11),
RP   TISSUE SPECIFICITY, AND VARIANTS PRO-41 AND ASP-4324.
RC   TISSUE=Pancreatic tumor;
RX   PubMed=10920259; DOI=10.1093/oxfordjournals.jbchem.a022746;
RA   Choudhury A., Moniaux N., Winpenny J.P., Hollingsworth M.A., Aubert J.-P.,
RA   Batra S.K.;
RT   "Human MUC4 mucin cDNA and its variants in pancreatic carcinoma.";
RL   J. Biochem. 128:233-243(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND VARIANTS PRO-41; ASP-4324 AND
RP   SER-4821.
RX   PubMed=12084055; DOI=10.1046/j.1432-1033.2002.02988.x;
RA   Desseyn J.-L., Clavereau I., Laine A.;
RT   "Cloning, chromosomal localization and characterization of the murine mucin
RT   gene orthologous to human MUC4.";
RL   Eur. J. Biochem. 269:3150-3159(2002).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 4257-5412 (ISOFORM 1), TISSUE SPECIFICITY,
RP   AND VARIANT ASP-4324.
RC   TISSUE=Colon mucosa;
RX   PubMed=10024507; DOI=10.1042/bj3380325;
RA   Moniaux N., Nollet S., Porchet N., Degand P., Laine A., Aubert J.-P.;
RT   "Complete sequence of the human mucin MUC4: a putative cell membrane-
RT   associated mucin.";
RL   Biochem. J. 338:325-333(1999).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 4257-5412, AND VARIANT ASP-4324.
RX   PubMed=12153560; DOI=10.1046/j.1432-1033.2002.03032.x;
RA   Escande F., Lemaitre L., Moniaux N., Batra S.K., Aubert J.-P.,
RA   Buisine M.P.;
RT   "Genomic organization of MUC4 mucin gene: towards the characterization of
RT   splice variants.";
RL   Eur. J. Biochem. 269:3637-3644(2002).
RN   [6]
RP   PRELIMINARY PARTIAL NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1673336; DOI=10.1016/0006-291x(91)91580-6;
RA   Porchet N., van Cong N., Dufosse J., Audie J.P., Guyonnet-Duperat V.,
RA   Gross M.S., Denis C., Degand P., Bernheim A., Aubert J.-P.;
RT   "Molecular cloning and chromosomal localization of a novel human tracheo-
RT   bronchial mucin cDNA containing tandemly repeated sequences of 48 base
RT   pairs.";
RL   Biochem. Biophys. Res. Commun. 175:414-422(1991).
RN   [7]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA   Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA   Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA   Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA   Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA   Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA   Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA   Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA   Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA   Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA   Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA   Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA   Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O.,
RA   Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X.,
RA   Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA   Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [8]
RP   DOMAIN, AND POLYMORPHISM.
RX   PubMed=9620877; DOI=10.1042/bj3320739;
RA   Nollet S., Moniaux N., Maury J., Petitprez D., Degand P., Laine A.,
RA   Porchet N., Aubert J.P.;
RT   "Human mucin gene MUC4: organization of its 5'-region and polymorphism of
RT   its central tandem repeat array.";
RL   Biochem. J. 332:739-748(1998).
RN   [9]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=12102554; DOI=10.1016/s0079-6603(02)71043-x;
RA   Carraway K.L., Perez A., Idris N., Jepson S., Arango M.E., Komatsu M.,
RA   Haq B., Price-Schiavi S.A., Zhang J., Carraway C.A.;
RT   "Muc4/sialomucin complex, the intramembrane ErbB2 ligand, in cancer and
RT   epithelia: to protect and to survive.";
RL   Prog. Nucleic Acid Res. Mol. Biol. 71:149-185(2002).
RN   [10]
RP   FUNCTION.
RX   PubMed=16049287; DOI=10.1136/jcp.2004.023572;
RA   Saitou M., Goto M., Horinouchi M., Tamada S., Nagata K., Hamada T.,
RA   Osako M., Takao S., Batra S.K., Aikou T., Imai K., Yonezawa S.;
RT   "MUC4 expression is a novel prognostic factor in patients with invasive
RT   ductal carcinoma of the pancreas.";
RL   J. Clin. Pathol. 58:845-852(2005).
RN   [11]
RP   TISSUE SPECIFICITY, AND FUNCTION.
RX   PubMed=16814944; DOI=10.1016/j.prp.2006.04.002;
RA   Karg A., Dinc Z.A., Basok O., Ucvet A.;
RT   "MUC4 expression and its relation to ErbB2 expression, apoptosis,
RT   proliferation, differentiation, and tumor stage in non-small cell lung
RT   cancer (NSCLC).";
RL   Pathol. Res. Pract. 202:577-583(2006).
RN   [12]
RP   DEVELOPMENTAL STAGE, AND FUNCTION.
RX   PubMed=16914178; DOI=10.1016/j.tice.2006.06.004;
RA   Zhang J., Yasin M., Carraway C.A., Carraway K.L.;
RT   "MUC4 expression and localization in gastrointestinal tract and skin of
RT   human embryos.";
RL   Tissue Cell 38:271-275(2006).
RN   [13]
RP   GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-5052.
RC   TISSUE=Milk;
RX   PubMed=18780401; DOI=10.1002/pmic.200701057;
RA   Picariello G., Ferranti P., Mamone G., Roepstorff P., Addeo F.;
RT   "Identification of N-linked glycoproteins in human milk by hydrophilic
RT   interaction liquid chromatography and mass spectrometry.";
RL   Proteomics 8:3833-3847(2008).
CC   -!- FUNCTION: Membrane-bound mucin, a family of highly glycosylated
CC       proteins that constitute the major component of the mucus, the slimy
CC       and viscous secretion covering epithelial surfaces (PubMed:10880978).
CC       These glycoproteins play important roles in the protection of the
CC       epithelium and are implicated in epithelial renewal and differentiation
CC       (PubMed:10880978). Regulates cellular behavior through both anti-
CC       adhesive effects on cell-cell and cell-extracellular matrix
CC       interactions and its ability to act as an intramembrane ligand for
CC       ERBB2. Plays an important role in proliferation and differentiation of
CC       epithelial cells by inducing specific phosphorylation of ERBB2. In
CC       polarized epithelial cells, segregates ERBB2 and other ERBB receptors
CC       and prevents ERBB2 from acting as a coreceptor. The interaction with
CC       ERBB2 leads to enhanced expression of CDKN1B. The formation of a MUC4-
CC       ERBB2-ERBB3-NRG1 complex leads to down-regulation of CDKN1B, resulting
CC       in repression of apoptosis and stimulation of proliferation. Its
CC       ability to promote tumor growth may be mainly due to repression of
CC       apoptosis as opposed to proliferation. {ECO:0000269|PubMed:12102554,
CC       ECO:0000269|PubMed:16049287, ECO:0000269|PubMed:16814944,
CC       ECO:0000269|PubMed:16914178, ECO:0000303|PubMed:10880978}.
CC   -!- SUBUNIT: A heterodimeric complex, composed of a mucin-4 alpha chain and
CC       a cysteine-rich transmembrane mucin-4 beta chain. Mucin-4 beta chain
CC       interacts with ERBB2 via the EGF-like domain 1. In nonpolarized cells,
CC       associates with ERBB2 and ERBB3. {ECO:0000250|UniProtKB:Q63661}.
CC   -!- SUBCELLULAR LOCATION: [Mucin-4 beta chain]: Cell membrane
CC       {ECO:0000303|PubMed:10880978}; Single-pass membrane protein
CC       {ECO:0000303|PubMed:10880978}. Note=Isoforms lacking the Cys-rich
CC       region, EGF-like domains and transmembrane region are secreted.
CC       Secretion occurs by splicing or proteolytic processing.
CC       {ECO:0000269|PubMed:12102554, ECO:0000303|PubMed:10880978}.
CC   -!- SUBCELLULAR LOCATION: [Mucin-4 alpha chain]: Cell membrane
CC       {ECO:0000303|PubMed:10880978}. Secreted {ECO:0000269|PubMed:12102554}.
CC       Note=Forms a complex with Mucin-4 beta chain at the cell membrane.
CC       {ECO:0000305|PubMed:10880978}.
CC   -!- SUBCELLULAR LOCATION: [Isoform 3]: Cell membrane
CC       {ECO:0000303|PubMed:10880978}; Single-pass membrane protein
CC       {ECO:0000303|PubMed:10880978}.
CC   -!- SUBCELLULAR LOCATION: [Isoform 11]: Secreted
CC       {ECO:0000303|PubMed:10880978}.
CC   -!- SUBCELLULAR LOCATION: [Isoform 15]: Secreted
CC       {ECO:0000303|PubMed:10880978}.
CC   -!- SUBCELLULAR LOCATION: [Isoform 17]: Cell membrane
CC       {ECO:0000303|PubMed:10880978}; Single-pass membrane protein
CC       {ECO:0000303|PubMed:10880978}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=14;
CC         Comment=Additional isoforms exist.;
CC       Name=1; Synonyms=Sv0-MUC4 {ECO:0000303|PubMed:10880978}, Sv21
CC       {ECO:0000303|PubMed:10920259};
CC         IsoId=Q99102-1; Sequence=Displayed;
CC       Name=2; Synonyms=Sv3-MUC4 {ECO:0000303|PubMed:10880978}, Sv4-MUC4
CC       {ECO:0000303|PubMed:10880978}, Sv5-MUC4 {ECO:0000303|PubMed:10880978},
CC       Sv12 {ECO:0000303|PubMed:10920259}, Sv13 {ECO:0000303|PubMed:10920259};
CC         IsoId=Q99102-2; Sequence=VSP_022658, VSP_022659;
CC       Name=3; Synonyms=Sv20 {ECO:0000303|PubMed:10920259}, sv7-MUC4
CC       {ECO:0000303|PubMed:10880978};
CC         IsoId=Q99102-3; Sequence=VSP_022674, VSP_022675;
CC       Name=5; Synonyms=Sv18 {ECO:0000303|PubMed:10920259}, Sv19
CC       {ECO:0000303|PubMed:10920259};
CC         IsoId=Q99102-5; Sequence=VSP_022661, VSP_022669, VSP_022670;
CC       Name=7; Synonyms=Sv16 {ECO:0000303|PubMed:10920259};
CC         IsoId=Q99102-7; Sequence=VSP_022656, VSP_022665;
CC       Name=8; Synonyms=Sv15 {ECO:0000303|PubMed:10920259};
CC         IsoId=Q99102-8; Sequence=VSP_022657, VSP_022664;
CC       Name=9; Synonyms=Sv11 {ECO:0000303|PubMed:10920259};
CC         IsoId=Q99102-9; Sequence=VSP_022652, VSP_022655;
CC       Name=10; Synonyms=Sv3, Sv17 {ECO:0000303|PubMed:10920259}, Sv10
CC       {ECO:0000303|PubMed:10920259};
CC         IsoId=Q99102-10; Sequence=VSP_022661;
CC       Name=11; Synonyms=Sv2 {ECO:0000303|PubMed:10880978}, Sv9
CC       {ECO:0000303|PubMed:10920259}, Sv14 {ECO:0000303|PubMed:10920259};
CC         IsoId=Q99102-11; Sequence=VSP_022653, VSP_022663;
CC       Name=12; Synonyms=SvX, MUC4/X {ECO:0000303|PubMed:10880978};
CC         IsoId=Q99102-12; Sequence=VSP_022650;
CC       Name=13; Synonyms=SvY, MUC4/Y {ECO:0000303|PubMed:10880978};
CC         IsoId=Q99102-13; Sequence=VSP_022651;
CC       Name=15; Synonyms=Sv1 {ECO:0000303|PubMed:10880978};
CC         IsoId=Q99102-15; Sequence=VSP_022654, VSP_022662;
CC       Name=16; Synonyms=Sv6-MUC4 {ECO:0000303|PubMed:10880978};
CC         IsoId=Q99102-16; Sequence=VSP_022671, VSP_022673;
CC       Name=17; Synonyms=Sv8-MUC4 {ECO:0000303|PubMed:10880978};
CC         IsoId=Q99102-17; Sequence=VSP_022672;
CC   -!- TISSUE SPECIFICITY: Expressed in the thymus, thyroid, lung, trachea,
CC       esophagus, stomach, small intestine, colon, testis, prostate, ovary,
CC       uterus, placenta, and mammary and salivary glands. Expressed in
CC       carcinomas arising from some of these epithelia, such as lung cancers,
CC       squamous cell carcinomas of the upper aerodigestive tract, mammary
CC       carcinomas, biliary tract, colon, and cervix cancers. Minimally or not
CC       expressed in the normal pancreas or chronic pancreatitis, but is highly
CC       expressed in pancreatic tumors and pancreatic tumor cell lines.
CC       {ECO:0000269|PubMed:10024507, ECO:0000269|PubMed:10880978,
CC       ECO:0000269|PubMed:10920259, ECO:0000269|PubMed:16814944}.
CC   -!- DEVELOPMENTAL STAGE: Expressed early in the primitive gut before
CC       respiratory and digestive epithelial cells have acquired their tissue
CC       and cell specificity. Expressed at the basal surface of the epithelium
CC       from week 14 to 26 weeks and then predominantly localized in only
CC       parietal cells. Immediately before birth, found in the cytoplasm of the
CC       mucous columnar epithelial cells. In the embryo expressed in skin, then
CC       disappears late in gestation. {ECO:0000269|PubMed:16914178}.
CC   -!- DOMAIN: [Mucin-4 alpha chain]: Essentially composed of an array of
CC       serine- and threonine-rich tandem repeats which is highly polymorphic,
CC       the variable number of tandem repeats (VNTR) region.
CC       {ECO:0000269|PubMed:9620877}.
CC   -!- PTM: Proteolytically cleaved into 2 chains, mucin-4 alpha chain and
CC       mucin-4 beta chain. {ECO:0000303|PubMed:10880978}.
CC   -!- PTM: [Mucin-4 alpha chain]: Highly O-glycosylated.
CC       {ECO:0000269|PubMed:18780401}.
CC   -!- PTM: [Mucin-4 beta chain]: Is predominantly N-glycosylated.
CC       {ECO:0000269|PubMed:18780401}.
CC   -!- POLYMORPHISM: The variable number of tandem repeats (VNTR) region, an
CC       array of serine- and threonine-rich tandem repeats, is encoded by a
CC       single exon (exon 2) which is highly polymorphic.
CC       {ECO:0000269|PubMed:9620877}.
CC   -!- MISCELLANEOUS: Expression is a very useful predictor of poor prognosis
CC       in patients with invasive ductal carcinoma and intrahepatic
CC       cholangiocarcinoma, mass forming type (IDC,ICC-MF). Patients with IDC
CC       or ICC-MF who have high MUC4 expression had a worse survival rate than
CC       those with low MUC4 expression.
CC   -!- MISCELLANEOUS: [Isoform 2]: May be produced at very low levels due to a
CC       premature stop codon in the mRNA, leading to nonsense-mediated mRNA
CC       decay. {ECO:0000305}.
CC   -!- MISCELLANEOUS: [Isoform 3]: May be produced at very low levels due to a
CC       premature stop codon in the mRNA, leading to nonsense-mediated mRNA
CC       decay. {ECO:0000305}.
CC   -!- MISCELLANEOUS: [Isoform 5]: May be produced at very low levels due to a
CC       premature stop codon in the mRNA, leading to nonsense-mediated mRNA
CC       decay. {ECO:0000305}.
CC   -!- MISCELLANEOUS: [Isoform 7]: May be produced at very low levels due to a
CC       premature stop codon in the mRNA, leading to nonsense-mediated mRNA
CC       decay. {ECO:0000305}.
CC   -!- MISCELLANEOUS: [Isoform 8]: May be produced at very low levels due to a
CC       premature stop codon in the mRNA, leading to nonsense-mediated mRNA
CC       decay. {ECO:0000305}.
CC   -!- MISCELLANEOUS: [Isoform 9]: Dubious isoform produced through aberrant
CC       splice sites. {ECO:0000305}.
CC   -!- MISCELLANEOUS: [Isoform 11]: May be produced at very low levels due to
CC       a premature stop codon in the mRNA, leading to nonsense-mediated mRNA
CC       decay. {ECO:0000305}.
CC   -!- MISCELLANEOUS: [Isoform 12]: May be preferentially expressed in tumor
CC       tissues. {ECO:0000305|PubMed:10880978}.
CC   -!- MISCELLANEOUS: [Isoform 13]: May be preferentially expressed in tumor
CC       tissues. {ECO:0000305|PubMed:10880978}.
CC   -!- MISCELLANEOUS: [Isoform 15]: May be produced at very low levels due to
CC       a premature stop codon in the mRNA, leading to nonsense-mediated mRNA
CC       decay. {ECO:0000305}.
CC   -!- MISCELLANEOUS: [Isoform 16]: Dubious isoform produced through aberrant
CC       splice sites. {ECO:0000305}.
CC   -!- MISCELLANEOUS: [Isoform 17]: Dubious isoform produced through aberrant
CC       splice sites. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA63230.1; Type=Miscellaneous discrepancy; Note=May be derived from an intron translation.; Evidence={ECO:0000305};
CC       Sequence=CAC14139.1; Type=Frameshift; Evidence={ECO:0000305};
CC       Sequence=CAC14141.1; Type=Frameshift; Evidence={ECO:0000305};
CC   -!- WEB RESOURCE: Name=Mucin database;
CC       URL="http://www.medkem.gu.se/mucinbiology/databases/";
CC   -!- WEB RESOURCE: Name=Atlas of Genetics and Cytogenetics in Oncology and
CC       Haematology;
CC       URL="https://atlasgeneticsoncology.org/gene/41459/MUC4";
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DR   EMBL; AJ242541; CAB85597.1; -; mRNA.
DR   EMBL; AJ242542; CAB85598.1; -; mRNA.
DR   EMBL; AJ242543; CAB85599.1; -; mRNA.
DR   EMBL; AJ242544; CAB85600.1; -; mRNA.
DR   EMBL; AJ242545; CAB85601.1; -; mRNA.
DR   EMBL; AJ242546; CAB85602.1; -; mRNA.
DR   EMBL; AJ242547; CAB85603.1; -; mRNA.
DR   EMBL; AJ242548; CAB85604.1; -; mRNA.
DR   EMBL; AJ242549; CAB85605.1; -; mRNA.
DR   EMBL; AJ242550; CAB85606.1; -; mRNA.
DR   EMBL; AJ276359; CAB81773.1; -; mRNA.
DR   EMBL; AJ277412; CAC10061.1; -; mRNA.
DR   EMBL; AJ277505; CAC14585.1; -; mRNA.
DR   EMBL; AJ400633; CAC10062.1; -; mRNA.
DR   EMBL; AJ400849; CAC14134.1; -; mRNA.
DR   EMBL; AJ400850; CAC14135.1; -; mRNA.
DR   EMBL; AJ400851; CAC14136.1; -; mRNA.
DR   EMBL; AJ400852; CAC14137.1; -; mRNA.
DR   EMBL; AJ400855; CAC14140.1; -; mRNA.
DR   EMBL; AJ400853; CAC14138.1; -; mRNA.
DR   EMBL; AJ400854; CAC14139.1; ALT_FRAME; mRNA.
DR   EMBL; AJ400856; CAC14141.1; ALT_FRAME; mRNA.
DR   EMBL; AJ400857; CAC14142.1; -; mRNA.
DR   EMBL; AJ400858; CAC14143.1; -; mRNA.
DR   EMBL; AF522055; AAM66747.1; -; Genomic_DNA.
DR   EMBL; AF522031; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522032; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522033; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522034; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522035; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522036; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522037; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522038; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522039; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522040; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522041; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522042; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522043; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522044; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522045; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522046; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522047; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522048; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522049; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522050; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522051; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522052; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522053; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AF522054; AAM66747.1; JOINED; Genomic_DNA.
DR   EMBL; AJ010901; CAB38059.1; -; mRNA.
DR   EMBL; AJ430032; CAD22550.1; -; Genomic_DNA.
DR   EMBL; AJ430033; CAD22550.1; JOINED; Genomic_DNA.
DR   EMBL; AJ430034; CAD22550.1; JOINED; Genomic_DNA.
DR   EMBL; M64594; AAA63230.1; ALT_SEQ; mRNA.
DR   EMBL; AC069513; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC233280; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS3310.1; -. [Q99102-13]
DR   CCDS; CCDS3311.1; -. [Q99102-12]
DR   CCDS; CCDS54700.1; -. [Q99102-1]
DR   PIR; PN0012; PN0012.
DR   RefSeq; NP_004523.3; NM_004532.5. [Q99102-13]
DR   RefSeq; NP_060876.5; NM_018406.6. [Q99102-1]
DR   RefSeq; NP_612154.2; NM_138297.4. [Q99102-12]
DR   AlphaFoldDB; Q99102; -.
DR   BioGRID; 110672; 7.
DR   IntAct; Q99102; 1.
DR   STRING; 9606.ENSP00000417498; -.
DR   GlyConnect; 374; 7 N-Linked glycans (3 sites), 8 O-Linked glycans.
DR   GlyCosmos; Q99102; 550 sites, 26 glycans.
DR   GlyGen; Q99102; 548 sites, 16 O-linked glycans (1 site).
DR   iPTMnet; Q99102; -.
DR   PhosphoSitePlus; Q99102; -.
DR   BioMuta; MUC4; -.
DR   DMDM; 338817990; -.
DR   jPOST; Q99102; -.
DR   MassIVE; Q99102; -.
DR   MaxQB; Q99102; -.
DR   PaxDb; 9606-ENSP00000417498; -.
DR   PeptideAtlas; Q99102; -.
DR   ProteomicsDB; 78234; -. [Q99102-1]
DR   ProteomicsDB; 78235; -. [Q99102-10]
DR   ProteomicsDB; 78236; -. [Q99102-11]
DR   ProteomicsDB; 78237; -. [Q99102-12]
DR   ProteomicsDB; 78238; -. [Q99102-13]
DR   ProteomicsDB; 78239; -. [Q99102-15]
DR   ProteomicsDB; 78240; -. [Q99102-16]
DR   ProteomicsDB; 78241; -. [Q99102-17]
DR   ProteomicsDB; 78242; -. [Q99102-2]
DR   ProteomicsDB; 78243; -. [Q99102-3]
DR   ProteomicsDB; 78244; -. [Q99102-5]
DR   ProteomicsDB; 78245; -. [Q99102-7]
DR   ProteomicsDB; 78246; -. [Q99102-8]
DR   ProteomicsDB; 78247; -. [Q99102-9]
DR   TopDownProteomics; Q99102-3; -. [Q99102-3]
DR   Antibodypedia; 1457; 446 antibodies from 38 providers.
DR   DNASU; 4585; -.
DR   Ensembl; ENST00000346145.8; ENSP00000304207.6; ENSG00000145113.22. [Q99102-13]
DR   Ensembl; ENST00000349607.8; ENSP00000338109.4; ENSG00000145113.22. [Q99102-12]
DR   Ensembl; ENST00000463781.8; ENSP00000417498.3; ENSG00000145113.22. [Q99102-1]
DR   Ensembl; ENST00000470451.5; ENSP00000420439.1; ENSG00000145113.22. [Q99102-7]
DR   Ensembl; ENST00000475231.5; ENSP00000420243.1; ENSG00000145113.22. [Q99102-10]
DR   Ensembl; ENST00000477086.5; ENSP00000419989.1; ENSG00000145113.22. [Q99102-2]
DR   Ensembl; ENST00000478156.5; ENSP00000419798.1; ENSG00000145113.22. [Q99102-3]
DR   GeneID; 4585; -.
DR   KEGG; hsa:4585; -.
DR   MANE-Select; ENST00000463781.8; ENSP00000417498.3; NM_018406.7; NP_060876.5.
DR   UCSC; uc003fvo.5; human. [Q99102-1]
DR   AGR; HGNC:7514; -.
DR   CTD; 4585; -.
DR   DisGeNET; 4585; -.
DR   GeneCards; MUC4; -.
DR   HGNC; HGNC:7514; MUC4.
DR   HPA; ENSG00000145113; Tissue enhanced (esophagus, intestine, prostate, vagina).
DR   MalaCards; MUC4; -.
DR   MIM; 158372; gene.
DR   neXtProt; NX_Q99102; -.
DR   OpenTargets; ENSG00000145113; -.
DR   PharmGKB; PA31319; -.
DR   VEuPathDB; HostDB:ENSG00000145113; -.
DR   eggNOG; ENOG502QUJ0; Eukaryota.
DR   GeneTree; ENSGT00730000110943; -.
DR   HOGENOM; CLU_001484_0_0_1; -.
DR   InParanoid; Q99102; -.
DR   OMA; DFTAPCV; -.
DR   OrthoDB; 2911509at2759; -.
DR   PathwayCommons; Q99102; -.
DR   Reactome; R-HSA-5083625; Defective GALNT3 causes HFTC.
DR   Reactome; R-HSA-5083632; Defective C1GALT1C1 causes TNPS.
DR   Reactome; R-HSA-5083636; Defective GALNT12 causes CRCS1.
DR   Reactome; R-HSA-5621480; Dectin-2 family.
DR   Reactome; R-HSA-913709; O-linked glycosylation of mucins.
DR   Reactome; R-HSA-977068; Termination of O-glycan biosynthesis.
DR   SignaLink; Q99102; -.
DR   SIGNOR; Q99102; -.
DR   BioGRID-ORCS; 4585; 12 hits in 1154 CRISPR screens.
DR   ChiTaRS; MUC4; human.
DR   GeneWiki; MUC4; -.
DR   GenomeRNAi; 4585; -.
DR   Pharos; Q99102; Tbio.
DR   PRO; PR:Q99102; -.
DR   Proteomes; UP000005640; Chromosome 3.
DR   RNAct; Q99102; Protein.
DR   Bgee; ENSG00000145113; Expressed in olfactory segment of nasal mucosa and 114 other cell types or tissues.
DR   ExpressionAtlas; Q99102; baseline and differential.
DR   GO; GO:0070062; C:extracellular exosome; HDA:UniProtKB.
DR   GO; GO:0031012; C:extracellular matrix; NAS:UniProtKB.
DR   GO; GO:0005615; C:extracellular space; HDA:UniProtKB.
DR   GO; GO:0005796; C:Golgi lumen; TAS:Reactome.
DR   GO; GO:0016020; C:membrane; NAS:UniProtKB.
DR   GO; GO:0005886; C:plasma membrane; TAS:Reactome.
DR   GO; GO:0031982; C:vesicle; HDA:UniProtKB.
DR   GO; GO:0005176; F:ErbB-2 class receptor binding; IBA:GO_Central.
DR   GO; GO:0030197; F:extracellular matrix constituent, lubricant activity; NAS:UniProtKB.
DR   GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR   GO; GO:0030277; P:maintenance of gastrointestinal epithelium; IMP:UniProtKB.
DR   CDD; cd00053; EGF; 1.
DR   InterPro; IPR005533; AMOP_dom.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR003886; NIDO_dom.
DR   InterPro; IPR001846; VWF_type-D.
DR   PANTHER; PTHR13802; MUCIN 4-RELATED; 1.
DR   PANTHER; PTHR13802:SF65; MUCIN-4; 1.
DR   Pfam; PF06119; NIDO; 1.
DR   Pfam; PF00094; VWD; 1.
DR   SMART; SM00723; AMOP; 1.
DR   SMART; SM00181; EGF; 3.
DR   SMART; SM00539; NIDO; 1.
DR   SMART; SM00216; VWD; 1.
DR   PROSITE; PS50856; AMOP; 1.
DR   PROSITE; PS00022; EGF_1; 1.
DR   PROSITE; PS50026; EGF_3; 2.
DR   PROSITE; PS51220; NIDO; 1.
DR   PROSITE; PS51233; VWFD; 1.
DR   Genevisible; Q99102; HS.
PE   1: Evidence at protein level;
KW   Alternative splicing; Cell adhesion; Cell membrane; Disulfide bond;
KW   EGF-like domain; Glycoprotein; Membrane; Reference proteome; Repeat;
KW   Secreted; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..5412
FT                   /note="Mucin-4"
FT                   /id="PRO_0000158956"
FT   CHAIN           29..4687
FT                   /note="Mucin-4 alpha chain"
FT                   /evidence="ECO:0000303|PubMed:10880978"
FT                   /id="PRO_0000274225"
FT   CHAIN           4688..5412
FT                   /note="Mucin-4 beta chain"
FT                   /evidence="ECO:0000303|PubMed:10880978"
FT                   /id="PRO_0000274226"
FT   TRANSMEM        5369..5389
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          4397..4552
FT                   /note="NIDO"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00570"
FT   DOMAIN          4553..4668
FT                   /note="AMOP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00347"
FT   DOMAIN          4680..4880
FT                   /note="VWFD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00580"
FT   DOMAIN          5118..5157
FT                   /note="EGF-like 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT   DOMAIN          5321..5360
FT                   /note="EGF-like 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT   REGION          40..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          43..4241
FT                   /note="Variable number of tandem repeats (VNTR)"
FT                   /evidence="ECO:0000269|PubMed:9620877"
FT   REGION          142..249
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          267..286
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          303..328
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          353..383
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          438..473
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          488..580
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          592..853
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          868..963
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          983..1864
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1878..2078
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2111..2220
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2232..2814
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2837..3306
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          3320..3580
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          3592..3644
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          3656..3756
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          3769..4223
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          4242..4288
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        304..328
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        488..530
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        543..580
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            4687..4688
FT                   /note="Cleavage"
FT                   /evidence="ECO:0000303|PubMed:10880978"
FT   CARBOHYD        154
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        156
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        230
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        234
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        255
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        364
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        369
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        376
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        617
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        620
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        666
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        688
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        747
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        797
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        798
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        802
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        804
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        813
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        814
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        881
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        886
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        892
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        931
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        934
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        938
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        943
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        945
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        948
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        952
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        954
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1003
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1007
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1012
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1019
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1022
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1023
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1028
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1030
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1035
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1039
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1044
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1051
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1055
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1060
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1062
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1067
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1071
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1076
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1083
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1086
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1087
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1092
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1094
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1099
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1103
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1108
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1110
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1115
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1118
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1119
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1124
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1126
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1131
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1135
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1172
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1179
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1182
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1183
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1188
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1195
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1199
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1204
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1236
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1243
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1246
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1247
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1278
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1279
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1284
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1286
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1291
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1295
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1300
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1307
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1311
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1316
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1323
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1326
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1332
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1339
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1342
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1343
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1348
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1380
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1387
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1390
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1391
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1396
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1403
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1407
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1412
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1444
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1451
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1454
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1455
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1486
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1487
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1492
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1494
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1499
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1503
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1508
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1515
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1519
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1524
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1531
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1534
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1540
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1547
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1550
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1551
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1556
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1563
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1566
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1567
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1572
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1579
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1582
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1583
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1588
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1590
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1598
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1599
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1604
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1611
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1614
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1615
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1620
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1622
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1627
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1630
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1637
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        1659
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1663
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1668
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1670
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1675
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1679
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1716
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1723
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1726
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1727
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1732
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1764
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1766
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1812
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1819
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1822
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1823
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1828
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1835
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1838
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1839
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1844
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1854
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1855
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1931
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1934
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1935
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1940
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1950
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1951
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1956
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1963
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1995
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        1999
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2004
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2006
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2015
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2020
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2027
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2030
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2031
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2036
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2038
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2047
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2052
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2062
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2063
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2132
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2137
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2139
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2142
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2143
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2148
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2150
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2155
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2159
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2164
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2180
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2182
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2187
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2191
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2196
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2198
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2203
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2207
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2244
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2254
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2255
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2283
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2286
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2287
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2292
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2299
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2303
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2308
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2324
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2331
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2334
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2335
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2340
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2347
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2351
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2356
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2363
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2366
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2367
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2372
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2382
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2383
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2388
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2395
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2398
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2399
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2406
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2437
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        2452
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2454
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2459
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2462
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2463
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2468
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2500
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2507
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2510
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2511
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2516
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2518
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2523
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2526
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2533
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        2564
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2566
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2571
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2575
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2580
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2582
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2587
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2590
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2591
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2596
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2598
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2619
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2622
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2623
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2628
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2660
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2667
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2670
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2671
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2676
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2683
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2687
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2692
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2694
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2740
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2742
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2750
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2751
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2756
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2758
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2763
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2767
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2773
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        2779
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2783
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2788
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2795
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2798
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2799
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2804
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2846
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2847
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2852
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2910
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2911
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2916
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2918
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2923
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2927
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2932
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2939
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2942
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2943
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2948
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2950
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2955
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2959
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2966
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2971
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        2975
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3023
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3028
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3035
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3039
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3071
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3076
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3078
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3083
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3087
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3092
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3099
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3102
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3103
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3108
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3115
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3118
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3119
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3124
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3126
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3131
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3135
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3140
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3142
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3147
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3150
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3151
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3156
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3158
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3163
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3167
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3172
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3179
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3182
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3183
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3188
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3220
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3227
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3230
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3231
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3236
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3243
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3247
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3252
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3254
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3294
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3332
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3339
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3342
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3343
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3348
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3350
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3355
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3359
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3397
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        3398
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3403
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3406
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3412
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3419
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3423
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3428
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3430
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3435
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3439
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3444
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3445
FT                   /note="O-linked (GalNAc...) serine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3446
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3451
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3454
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3455
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3460
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3462
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3467
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3470
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3471
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3476
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3483
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3486
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3487
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3492
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3499
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3502
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3504
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3508
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3515
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3519
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3524
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3526
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3531
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3535
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3540
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3547
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3550
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3551
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3556
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3567
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3614
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3615
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3622
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3678
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3679
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3686
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3691
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3695
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3700
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3710
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3711
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3716
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3718
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3723
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3727
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3732
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3739
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3743
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3748
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3780
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3787
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3790
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3791
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3796
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3798
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3803
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3807
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3812
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3822
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3823
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3828
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3835
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3839
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3844
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3851
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3854
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3860
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3867
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3871
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3876
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3883
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3886
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3887
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3892
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3894
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3899
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3903
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3935
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3940
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3942
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3947
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3950
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3951
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3956
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3958
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3963
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3967
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3972
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3979
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3983
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3988
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3990
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3995
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3999
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4004
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4006
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4011
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4015
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4020
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4021
FT                   /note="O-linked (GalNAc...) serine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4023
FT                   /note="O-linked (GalNAc...) serine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4024
FT                   /note="O-linked (GalNAc...) serine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4026
FT                   /note="O-linked (GalNAc...) serine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4027
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4031
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4036
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4037
FT                   /note="O-linked (GalNAc...) serine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4038
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4043
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4046
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4047
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4053
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        4078
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4084
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4110
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4111
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4116
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4118
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4123
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4127
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4132
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4139
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4142
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4143
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4148
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4158
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4159
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4164
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4171
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4175
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4180
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4182
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4187
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4190
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4191
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4196
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4198
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4203
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4207
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4212
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4214
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4219
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4223
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4239
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4272
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4278
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4280
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4289
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4293
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4297
FT                   /note="O-linked (GalNAc...) threonine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4715
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        4768
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        4787
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        4796
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        4831
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        4852
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        4875
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        4902
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        4928
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        4946
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        4982
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        4997
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        5045
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        5052
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000269|PubMed:18780401"
FT   CARBOHYD        5100
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        5119
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        5185
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        5192
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        5292
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   DISULFID        5122..5133
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT   DISULFID        5127..5145
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT   DISULFID        5147..5156
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT   DISULFID        5324..5335
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT   DISULFID        5329..5344
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT   DISULFID        5346..5359
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00076"
FT   VAR_SEQ         29..4315
FT                   /note="Missing (in isoform 12)"
FT                   /evidence="ECO:0000303|PubMed:10880978"
FT                   /id="VSP_022650"
FT   VAR_SEQ         29..4264
FT                   /note="Missing (in isoform 13)"
FT                   /evidence="ECO:0000303|PubMed:10880978"
FT                   /id="VSP_022651"
FT   VAR_SEQ         4314..4350
FT                   /note="RGVSLFPYGAGAGDLEFVRRTVDFTSPLFKPATGFPL -> SPLWGRRRGPG
FT                   VRQEDRGLHLPTLQAGDWLPPWLLSP (in isoform 9)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022652"
FT   VAR_SEQ         4316..4430
FT                   /note="VSLFPYGAGAGDLEFVRRTVDFTSPLFKPATGFPLGSSLRDSLYFTDNGQII
FT                   FPESDYQIFSYPNPLPTGFTGRDPVALVAPFWDDADFSTGRGTTFYQEYETFYGEHSLL
FT                   VQQA -> EAIQEFPSSPMGQTPGTWSSSGGPWTSPPHSSSRRLASPLAPLSVIPSTSQ
FT                   TMARSSSQSQTTRFSPTPTHSQQASQAGTLWPWWLRSGTMLTSPLVGGPHFIRNTRRSM
FT                   VNTAC (in isoform 11)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022653"
FT   VAR_SEQ         4316..4420
FT                   /note="VSLFPYGAGAGDLEFVRRTVDFTSPLFKPATGFPLGSSLRDSLYFTDNGQII
FT                   FPESDYQIFSYPNPLPTGFTGRDPVALVAPFWDDADFSTGRGTTFYQEYETFY -> AI
FT                   QEFPSSPMGQTPGTWSSSGGPWTSPPHSSSRRLASPLAPLSVIPSTSQTMARSSSQSQT
FT                   TRFSPTPTHSQQASQAGTLWPWWLRSGTMLTSPLVGGPHFIRL (in isoform
FT                   15)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_022654"
FT   VAR_SEQ         4351..5412
FT                   /note="Missing (in isoform 9)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022655"
FT   VAR_SEQ         4360..4444
FT                   /note="FTDNGQIIFPESDYQIFSYPNPLPTGFTGRDPVALVAPFWDDADFSTGRGTT
FT                   FYQEYETFYGEHSLLVQQAESWIRKMTNNGGYK -> ASQAGTLWPWWLRSGTMLTSPL
FT                   VGGPHFIRATPTKPSSPRTGAGPMPCFSTRAVGCSGTWPSAQWRWLFRKQPTDVPASVG
FT                   EVSP (in isoform 7)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022656"
FT   VAR_SEQ         4360..4442
FT                   /note="FTDNGQIIFPESDYQIFSYPNPLPTGFTGRDPVALVAPFWDDADFSTGRGTT
FT                   FYQEYETFYGEHSLLVQQAESWIRKMTNNGG -> ASQAGTLWPWWLRSGTMLTSPLVG
FT                   GPHFIRATPTKPSSPRTGAGPMPCFSTRAVGCSGTWPSAQASRCSWASLVEMAFSKTAH
FT                   (in isoform 8)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022657"
FT   VAR_SEQ         4360..4400
FT                   /note="FTDNGQIIFPESDYQIFSYPNPLPTGFTGRDPVALVAPFWD -> ASQAGTL
FT                   WPWWLRSGTMLTSPLVGGPHFIRNTRRSMVNTAC (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022658"
FT   VAR_SEQ         4401..5412
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022659"
FT   VAR_SEQ         4415..4466
FT                   /note="Missing (in isoform 5 and isoform 10)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022661"
FT   VAR_SEQ         4421..5412
FT                   /note="Missing (in isoform 15)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_022662"
FT   VAR_SEQ         4431..5412
FT                   /note="Missing (in isoform 11)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022663"
FT   VAR_SEQ         4443..5412
FT                   /note="Missing (in isoform 8)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022664"
FT   VAR_SEQ         4445..5412
FT                   /note="Missing (in isoform 7)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022665"
FT   VAR_SEQ         4501..4510
FT                   /note="GNPVLMGFSS -> VEMAFSKTAH (in isoform 5)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022669"
FT   VAR_SEQ         4511..5412
FT                   /note="Missing (in isoform 5)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022670"
FT   VAR_SEQ         4579..4627
FT                   /note="VSCPCSWQQGRRDLRFQPVSIGRWGLGSRQLCSFTSWRGGVCCSYGPWG ->
FT                   AAPPRLAQPRPPTSSPLRLSTAPAAWAPSRSNGSLSLTTQSVSCWITRL (in
FT                   isoform 16)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_022671"
FT   VAR_SEQ         4597..4822
FT                   /note="Missing (in isoform 17)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_022672"
FT   VAR_SEQ         4628..5412
FT                   /note="Missing (in isoform 16)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_022673"
FT   VAR_SEQ         5057..5070
FT                   /note="VAGCKCDGGTFGRY -> LWGALSCVRTSPAL (in isoform 3)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022674"
FT   VAR_SEQ         5071..5412
FT                   /note="Missing (in isoform 3)"
FT                   /evidence="ECO:0000303|PubMed:10920259"
FT                   /id="VSP_022675"
FT   VARIANT         37
FT                   /note="G -> D (in dbSNP:rs2259292)"
FT                   /id="VAR_030211"
FT   VARIANT         41
FT                   /note="A -> P (in dbSNP:rs3107764)"
FT                   /evidence="ECO:0000269|PubMed:10920259,
FT                   ECO:0000269|PubMed:12084055"
FT                   /id="VAR_065261"
FT   VARIANT         156
FT                   /note="T -> A (in dbSNP:rs2293232)"
FT                   /id="VAR_030212"
FT   VARIANT         580
FT                   /note="S -> A (in dbSNP:rs2246901)"
FT                   /id="VAR_030213"
FT   VARIANT         716
FT                   /note="A -> T (in dbSNP:rs3749331)"
FT                   /id="VAR_056585"
FT   VARIANT         4324
FT                   /note="G -> D (in dbSNP:rs2259292)"
FT                   /evidence="ECO:0000269|PubMed:10024507,
FT                   ECO:0000269|PubMed:10880978, ECO:0000269|PubMed:10920259,
FT                   ECO:0000269|PubMed:12084055, ECO:0000269|PubMed:12153560"
FT                   /id="VAR_065262"
FT   VARIANT         4448
FT                   /note="A -> T (in dbSNP:rs2293232)"
FT                   /id="VAR_056586"
FT   VARIANT         4821
FT                   /note="A -> S (in dbSNP:rs2246901)"
FT                   /evidence="ECO:0000269|PubMed:12084055"
FT                   /id="VAR_056587"
FT   CONFLICT        111
FT                   /note="M -> METVTQ (in Ref. 2; CAB81773)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        300
FT                   /note="F -> V (in Ref. 2; CAB81773)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        377
FT                   /note="T -> I (in Ref. 2; CAB81773)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        398
FT                   /note="T -> I (in Ref. 2; CAB81773)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        524..525
FT                   /note="GT -> RA (in Ref. 2; CAB81773)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        587
FT                   /note="T -> I (in Ref. 2; CAB81773)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        641
FT                   /note="Q -> R (in Ref. 2; CAB81773)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        702
FT                   /note="D -> N (in Ref. 2; CAB81773)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        914
FT                   /note="R -> G (in Ref. 2; CAB81773)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        945
FT                   /note="T -> S (in Ref. 2; CAB81773)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        953
FT                   /note="E -> Q (in Ref. 2; CAB81773)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        4263
FT                   /note="P -> S (in Ref. 2; CAB81773)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        4437
FT                   /note="M -> I (in Ref. 1;
FT                   CAB85602/CAB85603/CAB85604/CAB85605/CAB85606, 2;
FT                   CAB81773/CAC14141/CAC14142/CAC14143, 3; AAM66747, 4;
FT                   CAD22550 and 5; CAB38059)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        4502
FT                   /note="N -> K (in Ref. 2; CAB81773/CAC14143/CAC10061 and 3;
FT                   AAM66747)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        4514
FT                   /note="Y -> F (in Ref. 2; CAB81773/CAC14143/CAC10061 and 3;
FT                   AAM66747)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        4548
FT                   /note="R -> G (in Ref. 2; CAB81773/CAC14143/CAC10061 and 3;
FT                   AAM66747)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        4800
FT                   /note="V -> A (in Ref. 2; CAB81773/CAC14143/CAC10061 and 3;
FT                   AAM66747)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        5163..5164
FT                   /note="Missing (in Ref. 2; CAC14143)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        5282
FT                   /note="G -> E (in Ref. 1; CAB85604/CAB85605/CAB85606, 4;
FT                   CAD22550 and 5; CAB38059)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   5412 AA;  542307 MW;  CA70610C2C0FC5B0 CRC64;
     MKGARWRRVP WVSLSCLCLC LLPHVVPGTT EDTLITGSKT AAPVTSTGST TATLEGQSTA
     ASSRTSNQDI SASSQNHQTK STETTSKAQT DTLTQMMTST LFSSPSVHNV METAPPDEMT
     TSFPSSVTNT LMMTSKTITM TTSTDSTLGN TEETSTAGTE SSTPVTSAVS ITAGQEGQSR
     TTSWRTSIQD TSASSQNHWT RSTQTTRESQ TSTLTHRTTS TPSFSPSVHN VTGTVSQKTS
     PSGETATSSL CSVTNTSMMT SEKITVTTST GSTLGNPGET SSVPVTGSLM PVTSAALVTF
     DPEGQSPATF SRTSTQDTTA FSKNHQTQSV ETTRVSQINT LNTLTPVTTS TVLSSPSGFN
     PSGTVSQETF PSGETTTSSP SSVSNTFLVT SKVFRMPTSR DSTLGNTEET SLSVSGTISA
     ITSKVSTIWW SDTLSTALSP SSLPPKISTA FHTQQSEGAE TTGRPHERSS FSPGVSQEIF
     TLHETTTWPS SFSSKGHTTW SQTELPSTST GAATRLVTGN PSTGTAGTIP RVPSKVSAIG
     EPGEPTTYSS HSTTLPKTTG AGAQTQWTQE TGTTGEALLS SPSYSVTQMI KTATSPSSSP
     MLDRHTSQQI TTAPSTNHST IHSTSTSPQE SPAVSQRGHT QAPQTTQESQ TTRSVSPMTD
     TKTVTTPGSS FTASGHSPSE IVPQDAPTIS AATTFAPAPT GDGHTTQAPT TALQAAPSSH
     DATLGPSGGT SLSKTGALTL ANSVVSTPGG PEGQWTSASA STSPDTAAAM THTHQAESTE
     ASGQTQTSEP ASSGSRTTSA GTATPSSSGA SGTTPSGSEG ISTSGETTRF SSNPSRDSHT
     TQSTTELLSA SASHGAIPVS TGMASSIVPG TFHPTLSEAS TAGRPTGQSS PTSPSASPQE
     TAAISRMAQT QRTRTSRGSD TISLASQATD TFSTVPPTPP SITSTGLTSP QTETHTLSPS
     GSGKTFTTAL ISNATPLPVT YASSASTGHT TPLHVTDASS VSTGHATPLP VTSPSSVSTG
     HTTPLPVTDT SSESTGHVTP LPVTSFSSAS TGDSTPLPVT DTSSASTGHV TPLPVTSLSS
     ASTGDTTPLP VTDTSSASTG HATSLPVTDT SSVSTGHTTP LPVTDTSSAS TGHATSLPVT
     DTSSVSTGHT TPLHVTDASS ASTGQATPLP VTSLSSVSTG DTTPLPVTSP SSASTGHATP
     LLVTDTSSAS TGHATPLPVT DASSVSTDHA TSLPVTIPSA ASTGHTTPLP VTDTSSASTG
     QATSLLVTDT SSVSTGDTTP LPVTSTSSAS TGHVTPLHVT SPSSASTGHA TPLPVTSLSS
     ASTGDTMPLP VTSPSSASTG DTTPLPVTDA SSVSTGHTTP LHVTDASSAS TGQATPLPVT
     SLSSVSTGDT TPLPVTSPSS ASTGHATPLL VTDTSSASTG HATPLPVTDA SSVSTDHATS
     LPVTIPSAAS TGHTTPLPVT DTSSASTGQA TSLLVTDTSS VSTGDTTPLP VTSTSSASTG
     HVTPLHVTSP SSASTGHATP LPVTSLSSAS TGDTMPLPVT SPSSASTGDT TPLPVTDASS
     VSTGHTTPLP VTSPSSASTG HTTPLPVTDT SSASKGDTTP LPVTSPSSAS TGHTTPLPVT
     DTSSASTGDT TPLPVTNASS LSTGHATPLH VTSPSSASTG HATPLPVTST SSASTGHATP
     LPVTGLSSAT TDDTTRLPVT DVSSASTGQA TPLPVTSLSS VSTGDTTPLP VTSPSSASTG
     HASPLLVTDA SSASTGQATP LPVTDTSSVS TAHATPLPVT GLSSASTDDT TRLPVTDVSS
     ASTGQAIPLP VTSPSSASTG DTTPLPVTDA SSASTGDTTS LPVTIPSSAS SGHTTSLPVT
     DASSVSTGHA TSLLVTDASS VSTGDTTPLP VTDTNSASTG DTTPLHVTDA SSVSTGHATS
     LPVTSLSSAS TGDTTPLPVT SPSSASSGHT TPLPVTDASS VPTGHATSLP VTDASSVSTG
     HATPLPVTDA SSVSTGHATP LPVTDTSSVS TGQATPLPVT SLSSASTGDT TPLPVTDTSS
     ASTGQDTPLP VTSLSSVSTG DTTPLPVTNP SSASTGHATP LLVTDASSIS TGHATSLLVT
     DASSVSTGHA TALHDTDASS LSTGDTTPLP VTSPSSTSTG DTTPLPVTET SSVSTGHATS
     LPVTDTSSAS TGHATSLPVT DTSSASTGHA TPLPVTDTSS ASTGQATPLP VTSPSSASTG
     HAIPLLVTDT SSASTGQATP LPVTSLSSAS TGDTTPLPVT DASSVSTGHA TSLPVTSLSS
     VSTGDTTPLP VTSPSSASTG HATPLHVTDA SSASTGHATP LPVTSLSSAS TGDTTPLPVT
     SPSSASTGHA TPLHVTDASS VSTGDTTPLP VTSSSSASSG HTTPLPVTDA SSASTGDTTP
     LPVTDTSSAS TGHATHLPVT GLSSASTGDT TRLPVTNVSS ASTGHATPLP VTSTSSASTG
     DTTPLPGTDT SSVSTGHTTP LLVTDASSVS TGDTTRLPVT SPSSASTGHT TPLPVTDTPS
     ASTGDTTPLP VTNASSLSTR HATSLHVTSP SSASTGHATS LPVTDTSAAS TGHATPLPVT
     STSSASTGDT TPLPVTDTYS ASTGQATPLP VTSLSSVSTG DTTPLPVTSP SSASTGHATP
     LLVTDASSAS TGQATPLPVT SLSSVSTGDT TPLPVTSPSS ASTGHATSLP VTDTSSASTG
     DTTSLPVTDT SSAYTGDTTS LPVTDTSSSS TGDTTPLLVT ETSSVSTGDT TPLPVTDTSS
     ASTGHATPLP VTNTSSVSTG HATPLHVTSP SSASTGHTTP LPVTDASSVS TGHATSLPVT
     DASSVFTGHA TSLPVTIPSS ASSGHTTPLP VTDASSVSTG HATSLPVTDA SSVSTGHATP
     LPVTDASSVS TGHATPLPLT SLSSVSTGDT TPLPVTDTSS ASTGQATPLP VTSLSSVSTG
     DTTPLPVTDT SSASTGHATS LPVTDTSSAS TGHATPLPDT DTSSASTGHA TLLPVTDTSS
     ASIGHATSLP VTDTSSISTG HATPLHVTSP SSASTGHATP LPVTDTSSAS TGHANPLHVT
     SPSSASTGHA TPLPVTDTSS ASTGHATPLP VTSLSSVSTG DTTPLPVTSP SSASTGHTTP
     LPVTDTSSAS TGQATALPVT STSSASTGDT TPLPVTDTSS ASTGQATPLP VTSLSSVSTG
     DTTPLPVTSP SSASTGHATP LLVTDASSAS TGQATPLPVT SLSSVSTGDT TPLPVTSPSS
     ASTGHATSLP VTDTSSASTG DTTSLPVTDT SSAYTGDTTS LPVTDTSSSS TGDTTPLLVT
     ETSSVSTGHA TPLLVTDASS ASTGHATPLH VTSPSSASTG DTTPVPVTDT SSVSTGHATP
     LPVTGLSSAS TGDTTRLPVT DISSASTGQA TPLPVTNTSS VSTGDTMPLP VTSPSSASTG
     HATPLPVTST SSASTGHATP VPVTSTSSAS TGHTTPLPVT DTSSASTGDT TPLPVTSPSS
     ASTGHTTPLH VTIPSSASTG DTSTLPVTGA SSASTGHATP LPVTDTSSVS TGHATPLPVT
     SLSSVSTGDT TPLPVTDASS ASTGQATPLP VTSLSSVSTG DTTPLLVTDA SSVSTGHATP
     LPVTDTSSAS TGDTTRLPVT DTSSASTGQA TPLPVTSLSS VSTGDTTPLL VTDASSVSTG
     HATPLPVTDT SSASTGDTTR LPVTDTSSAS TGQATPLPVT IPSSSSSGHT TPLPVTSTSS
     VSTGHVTPLH VTSPSSASTG HVTPLPVTST SSASTGHATP LLVTDASSVS TGHATPLPVT
     DASSASTGDT TPLPVTDTSS ASTGQATPLP VTSLSSVSTG DTTPLPVTDA SSASTGHATP
     LPVTIPSSVS TGDTMPLPVT SPSSASTGHA TPLPVTGLSS ASTGDTTPLP VTDTSSASTR
     HATPLPVTDT SSASTDDTTR LPVTDVSSAS TGHATPLPVT STSSASTGDT TPLPVTDTSS
     VSTGHATSLP VTSRSSASTG HATPLPVTDT SSVSTGHATP LPVTSTSSVS TGHATPLPVT
     SPSSASTGHA TPVPVTSTSS ASTGDTTPLP VTNASSLSTG HATPLHVTSP SSASRGDTST
     LPVTDASSAS TGHATPLPLT SLSSVSTGDT TPLPVTDTSS ASTGQATPLP VTSLSSVSTG
     DTTPLPVTIP SSASSGHTTS LPVTDASSVS TGHGTPLPVT STSSASTGDT TPLPVTDTSS
     ASTGHATPLP VTDTSSASTG HATPLPVTSL SSVSTGHATP LAVSSATSAS TVSSDSPLKM
     ETPGMTTPSL KTDGGRRTAT SPPPTTSQTI ISTIPSTAMH TRSTAAPIPI LPERGVSLFP
     YGAGAGDLEF VRRTVDFTSP LFKPATGFPL GSSLRDSLYF TDNGQIIFPE SDYQIFSYPN
     PLPTGFTGRD PVALVAPFWD DADFSTGRGT TFYQEYETFY GEHSLLVQQA ESWIRKMTNN
     GGYKARWALK VTWVNAHAYP AQWTLGSNTY QAILSTDGSR SYALFLYQSG GMQWDVAQRS
     GNPVLMGFSS GDGYFENSPL MSQPVWERYR PDRFLNSNSG LQGLQFYRLH REERPNYRLE
     CLQWLKSQPR WPSWGWNQVS CPCSWQQGRR DLRFQPVSIG RWGLGSRQLC SFTSWRGGVC
     CSYGPWGEFR EGWHVQRPWQ LAQELEPQSW CCRWNDKPYL CALYQQRRPH VGCATYRPPQ
     PAWMFGDPHI TTLDGVSYTF NGLGDFLLVG AQDGNSSFLL QGRTAQTGSA QATNFIAFAA
     QYRSSSLGPV TVQWLLEPHD AIRVLLDNQT VTFQPDHEDG GGQETFNATG VLLSRNGSEV
     SASFDGWATV SVIALSNILH ASASLPPEYQ NRTEGLLGVW NNNPEDDFRM PNGSTIPPGS
     PEEMLFHFGM TWQINGTGLL GKRNDQLPSN FTPVFYSQLQ KNSSWAEHLI SNCDGDSSCI
     YDTLALRNAS IGLHTREVSK NYEQANATLN QYPPSINGGR VIEAYKGQTT LIQYTSNAED
     ANFTLRDSCT DLELFENGTL LWTPKSLEPF TLEILARSAK IGLASALQPR TVVCHCNAES
     QCLYNQTSRV GNSSLEVAGC KCDGGTFGRY CEGSEDACEE PCFPSVHCVP GKGCEACPPN
     LTGDGRHCAA LGSSFLCQNQ SCPVNYCYNQ GHCYISQTLG CQPMCTCPPA FTDSRCFLAG
     NNFSPTVNLE LPLRVIQLLL SEEENASMAE VNASVAYRLG TLDMRAFLRN SQVERIDSAA
     PASGSPIQHW MVISEFQYRP RGPVIDFLNN QLLAAVVEAF LYHVPRRSEE PRNDVVFQPI
     SGEDVRDVTA LNVSTLKAYF RCDGYKGYDL VYSPQSGFTC VSPCSRGYCD HGGQCQHLPS
     GPRCSCVSFS IYTAWGEHCE HLSMKLDAFF GIFFGALGGL LLLGVGTFVV LRFWGCSGAR
     FSYFLNSAEA LP
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