ID   OXDA_TRIVR              Reviewed;         356 AA.
AC   Q99042;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   16-JUN-2009, entry version 50.
DE   RecName: Full=D-amino-acid oxidase;
DE            Short=DAMOX;
DE            Short=DAAO;
DE            Short=DAO;
DE            EC=1.4.3.3;
GN   Name=DAO1;
OS   Trigonopsis variabilis (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; mitosporic Saccharomycetales;
OC   Trigonopsis.
OX   NCBI_TaxID=34364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CBS 4095;
RX   MEDLINE=98095789; PubMed=9434346;
RX   DOI=10.1002/(SICI)1097-0061(199712)13:15<1399::AID-YEA187>3.3.CO;2-Z;
RA   Gonzalez F.J., Montes J., Martin F., Lopez M.C., Ferminan E.,
RA   Catalan J., Galan M.A., Dominguez A.;
RT   "Molecular cloning of TvDAO1, a gene encoding a D-amino acid oxidase
RT   from Trigonopsis variabilis and its expression in Saccharomyces
RT   cerevisiae and Kluyveromyces lactis.";
RL   Yeast 13:1399-1408(1997).
CC   -!- CATALYTIC ACTIVITY: A D-amino acid + H(2)O + O(2) = a 2-oxo acid +
CC       NH(3) + H(2)O(2).
CC   -!- COFACTOR: FAD.
CC   -!- SIMILARITY: Belongs to the DAMOX/DASOX family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; Z50019; CAA90322.1; -; Genomic_DNA.
DR   PIR; S39437; S39437.
DR   HSSP; P80324; 1C0P.
DR   BRENDA; 1.4.3.3; 142970.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0003884; F:D-amino-acid oxidase activity; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR006181; D-amino_acid_oxidase_CS.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR013027; FAD_pyr_nucl-diS_OxRdtase.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Pfam; PF01266; DAO; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PROSITE; PS00677; DAO; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase.
FT   CHAIN         1    356       D-amino-acid oxidase.
FT                                /FTId=PRO_0000162768.
FT   NP_BIND       4     18       FAD (By similarity).
FT   NP_BIND      32     33       FAD (By similarity).
FT   NP_BIND      43     44       FAD (By similarity).
FT   NP_BIND      48     50       FAD (By similarity).
FT   NP_BIND     329    333       FAD (By similarity).
FT   BINDING     171    171       FAD; via amide nitrogen and carbonyl
FT                                oxygen (By similarity).
FT   BINDING     194    194       FAD (By similarity).
FT   BINDING     243    243       Substrate (By similarity).
FT   BINDING     302    302       Substrate (By similarity).
FT   BINDING     330    330       Substrate; via carbonyl oxygen (By
FT                                similarity).
SQ   SEQUENCE   356 AA;  39301 MW;  A2935E9DB71A49FC CRC64;
     MAKIVVIGAG VAGLTTALQL LRKGHEVTIV SEFTPGDLSI GYTSPWAGAN WLTFYDGGKL
     ADYDAVSYPI LRELARSSPE AGIRLISQRS HVLKRDLPKL EVAMSAICQR NPWFKNTVDS
     FEIIEDRSRI VHDDVAYLVE FRSVCIHTGV YLNWLMSQCL SLGATVVKRR VNHIKDANLL
     HSSGSRPDVI VNCSGLFARF LGGVEDKKMY PIRGQVVLVR NSLPFMASFS STPEKENEDE
     ALYIMTRFDG TSIIGGCFQP NNWSSEPDPS LTHRILSRAL DRFPELTKDG PLDIVRECVG
     HRPGREGGPR VELEKIPGVG FVVHNYGAAG AGYQSSYGMA DEAVSYVERA LTRPNL
//