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Q98ZP7

- Q98ZP7_SV40

UniProt

Q98ZP7 - Q98ZP7_SV40

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Protein
Submitted name:

Truncated large tumor antigen

Gene
N/A
Organism
Simian virus 40 (SV40)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA replication origin binding Source: InterPro
  3. hydrolase activity Source: UniProtKB-KW

GO - Biological processi

  1. DNA replication Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseSAAS annotations

Keywords - Ligandi

ATP-bindingSAAS annotations, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Truncated large tumor antigenImported
OrganismiSimian virus 40 (SV40)Imported
Taxonomic identifieri10633 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePolyomaviridaePolyomavirus
Virus hostiMacaca (macaques) [TaxID: 9539]

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2IF9X-ray2.59A/B131-260[»]
2IPRX-ray1.50A/B131-259[»]
2ITJX-ray2.50A/B131-259[»]
2ITLX-ray1.65A/B131-259[»]
2NL8X-ray2.30A131-259[»]
2NTCX-ray2.40A/B131-260[»]
2TBDNMR-A131-260[»]
ProteinModelPortaliQ98ZP7.
SMRiQ98ZP7. Positions 7-117, 131-260, 265-509.

Family & Domainsi

Sequence similaritiesi

Contains SF3 helicase domain.SAAS annotations
Contains SFhelicase domain.SAAS annotations

Family and domain databases

Gene3Di1.10.10.510. 1 hit.
1.10.287.110. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR001623. DnaJ_domain.
IPR014015. Helicase_SF3_DNA-vir.
IPR010932. Lg_T_Ag_Polyomavir_C.
IPR027417. P-loop_NTPase.
IPR003133. T_Ag_DNA-bd.
IPR017910. Znf_lg_T-Ag_D1-typ.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
PF06431. Polyoma_lg_T_C. 1 hit.
PF02217. T_Ag_DNA_bind. 1 hit.
[Graphical view]
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS50076. DNAJ_2. 1 hit.
PS51206. SF3_HELICASE_1. 1 hit.
PS51287. T_AG_OBD. 1 hit.
PS51341. ZF_LTAG_D1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q98ZP7-1 [UniParc]FASTAAdd to Basket

« Hide

MDKVLNREES LQLMDLLGLE RSAWGNIPLM RKAYLKKCKE FHPDKGGDEE    50
KMKKMNTLYK KMEDGVKYAH QPDFGGFWDA TEIPTYGTDE WEQWWNAFNE 100
ENLFCSEEMP SSDDEATADS QHSTPPKKKR KVEDPKDFPS ELLSFLSHAV 150
FSNRTLACFA IYTTKEKAAL LYKKIMEKYS VTFISRHNSY NHNILFFLTP 200
HRHRVSAINN YAQKLCTFSF LICKGVNKEY LMYSALTRDP FSVIEESLPG 250
GLKEHDFNPE EAEETKQVSW KLVTEYAMET KCDDVLLLLG MYLEFQYSFE 300
MCLKCIKKEQ PSHYKYHEKH YANAAIFADS KNQKTICQQA VDTVLAKKRV 350
DSLQLTREQM LTNRFNDLLD RMDIMFGSTG SADIEEWMAG VAWLHCLLPK 400
MDSVVYDFLK CMVYNIPKKR YWLFKGPIDS GKTTLAAALL ELCGGKALNV 450
NLPLDRLNFE LGVAIDQFLV VFEDVKGTGG ESRDLPSGQG INNLSHITSV 500
EVLLALKNLP HLPLNLKHKM NAIVVVNLFI AAYNGYK 537
Length:537
Mass (Da):61,675
Last modified:June 1, 2001 - v1
Checksum:i3337EFB55B957FA1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF345345 Genomic DNA. Translation: AAK29054.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF345345 Genomic DNA. Translation: AAK29054.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2IF9 X-ray 2.59 A/B 131-260 [» ]
2IPR X-ray 1.50 A/B 131-259 [» ]
2ITJ X-ray 2.50 A/B 131-259 [» ]
2ITL X-ray 1.65 A/B 131-259 [» ]
2NL8 X-ray 2.30 A 131-259 [» ]
2NTC X-ray 2.40 A/B 131-260 [» ]
2TBD NMR - A 131-260 [» ]
ProteinModelPortali Q98ZP7.
SMRi Q98ZP7. Positions 7-117, 131-260, 265-509.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.10.10.510. 1 hit.
1.10.287.110. 1 hit.
3.40.50.300. 1 hit.
InterProi IPR001623. DnaJ_domain.
IPR014015. Helicase_SF3_DNA-vir.
IPR010932. Lg_T_Ag_Polyomavir_C.
IPR027417. P-loop_NTPase.
IPR003133. T_Ag_DNA-bd.
IPR017910. Znf_lg_T-Ag_D1-typ.
[Graphical view ]
Pfami PF00226. DnaJ. 1 hit.
PF06431. Polyoma_lg_T_C. 1 hit.
PF02217. T_Ag_DNA_bind. 1 hit.
[Graphical view ]
SMARTi SM00271. DnaJ. 1 hit.
[Graphical view ]
SUPFAMi SSF46565. SSF46565. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEi PS50076. DNAJ_2. 1 hit.
PS51206. SF3_HELICASE_1. 1 hit.
PS51287. T_AG_OBD. 1 hit.
PS51341. ZF_LTAG_D1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Solution structure of the origin DNA-binding domain of SV40 T-antigen."
    Luo X., Sanford D.G., Bullock P.A., Bachovchin W.W.
    Nat. Struct. Biol. 3:1034-1039(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR OF 131-260.
  2. "Complete DNA sequence of SV40-GM00637H, defective variant 12."
    Lednicky J.A., Butel J.S., Lewis A.M.
    Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: GM00637HImported.
  3. "Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA."
    Bochkareva E., Martynowski D., Seitova A., Bochkarev A.
    EMBO J. 25:5961-5969(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) OF 131-259.
  4. "The crystal structure of the SV40 T-antigen origin binding domain in complex with DNA."
    Meinke G., Phelan P., Moine S., Bochkareva E., Bochkarev A., Bullock P.A., Bohm A.
    PLoS Biol. 5:e23-e23(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 131-260.

Entry informationi

Entry nameiQ98ZP7_SV40
AccessioniPrimary (citable) accession number: Q98ZP7
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: April 16, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3

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