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Protein

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

Gene
N/A
Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Cofactori

(R)-lipoateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Enzyme and pathway databases

BRENDAi2.3.1.168 1306

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.-UniRule annotation)
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Structurei

3D structure databases

ProteinModelPortaliQ98UJ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini64 – 139Lipoyl-bindingInterPro annotationAdd BLAST76
Domaini174 – 211Peripheral subunit-binding (PSBD)InterPro annotationAdd BLAST38

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Keywords - Domaini

LipoylUniRule annotation

Phylogenomic databases

eggNOGiKOG0558 Eukaryota
COG0508 LUCA
HOGENOMiHOG000281564
HOVERGENiHBG104085
KOiK09699
PhylomeDBiQ98UJ6

Family and domain databases

Gene3Di3.30.559.10, 1 hit
4.10.320.10, 1 hit
InterProiView protein in InterPro
IPR003016 2-oxoA_DH_lipoyl-BS
IPR001078 2-oxoacid_DH_actylTfrase
IPR015761 BCKADH_E2
IPR000089 Biotin_lipoyl
IPR023213 CAT-like_dom_sf
IPR036625 E3-bd_dom_sf
IPR004167 PSBD
IPR011053 Single_hybrid_motif
PANTHERiPTHR43178:SF5 PTHR43178:SF5, 1 hit
PfamiView protein in Pfam
PF00198 2-oxoacid_dh, 1 hit
PF00364 Biotin_lipoyl, 1 hit
PF02817 E3_binding, 1 hit
SUPFAMiSSF47005 SSF47005, 1 hit
SSF51230 SSF51230, 1 hit
PROSITEiView protein in PROSITE
PS50968 BIOTINYL_LIPOYL, 1 hit
PS00189 LIPOYL, 1 hit
PS51826 PSBD, 1 hit

Sequencei

Sequence statusi: Complete.

Q98UJ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAVTTLRSS CRTAGRLVCV HHIRSCSSIR FIKSKYACVF DKSAFNFSHQ
60 70 80 90 100
QRLFRTSAVS HGQIVQFKLS DIGEGITEVT VKEWYIKEGD SVSQFDSICE
110 120 130 140 150
VQSDKASVTI TSRYDGIIRK LHYNLDEIAY VGKPLVDIEI DASKGVAPEE
160 170 180 190 200
DVVETPAMSH EEHTHQEIKG HKTLATPAVR RLAMENNIKL SEVIGTGKDN
210 220 230 240 250
RILKEDILSF LAKQTGAILP PSPKAEIIAP LSKSETVPTA PKDKARKIPI
260 270 280 290 300
PISRPVVFSG KDKTEPITGF HKAMVKTMSA ALKIPHFGYC DEIDLTHLVQ
310 320 330 340 350
LREELKPLAQ SRGVKLSFMP FFIKAASLGL LQYPILNASL DEGCQNVTYK
360 370 380 390 400
ASHNIGVAMD TEQGLIVPNV KNVQVSSIFE IASELNRLQA LGSASQLGTN
410 420 430 440 450
DLTGGTFTLS NIGTIGGTYA KAVILPPEVA IGALGKIQVL PRFNGKGEVF
460 470 480 490
KAQIMNVSWS ADHRIIDGAT MARFSNLWKS YLENPALMLL DLK
Length:493
Mass (Da):53,998
Last modified:June 1, 2001 - v1
Checksum:i196C1B38EA476F1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB035085 mRNA Translation: BAB32667.1
RefSeqiNP_989987.1, NM_204656.1
UniGeneiGga.187

Genome annotation databases

GeneIDi395374
KEGGigga:395374

Similar proteinsi

Entry informationi

Entry nameiQ98UJ6_CHICK
AccessioniPrimary (citable) accession number: Q98UJ6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: March 28, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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