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Protein

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

Gene
N/A
Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

(R)-lipoateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

AcyltransferaseUniRule annotationImported, Transferase

Enzyme and pathway databases

BRENDAi2.3.1.168. 1306.

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.-UniRule annotation)
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

PTM / Processingi

Proteomic databases

PaxDbiQ98UJ6.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000008453.

Structurei

3D structure databases

ProteinModelPortaliQ98UJ6.
SMRiQ98UJ6. Positions 62-144, 165-222, 260-493.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini64 – 13976Lipoyl-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Keywords - Domaini

LipoylUniRule annotation

Phylogenomic databases

eggNOGiKOG0558. Eukaryota.
COG0508. LUCA.
HOGENOMiHOG000281564.
HOVERGENiHBG104085.
KOiK09699.
PhylomeDBiQ98UJ6.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR015761. BCKDC_E2.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR011053. Single_hybrid_motif.
[Graphical view]
PANTHERiPTHR23151:SF71. PTHR23151:SF71. 2 hits.
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q98UJ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAVTTLRSS CRTAGRLVCV HHIRSCSSIR FIKSKYACVF DKSAFNFSHQ
60 70 80 90 100
QRLFRTSAVS HGQIVQFKLS DIGEGITEVT VKEWYIKEGD SVSQFDSICE
110 120 130 140 150
VQSDKASVTI TSRYDGIIRK LHYNLDEIAY VGKPLVDIEI DASKGVAPEE
160 170 180 190 200
DVVETPAMSH EEHTHQEIKG HKTLATPAVR RLAMENNIKL SEVIGTGKDN
210 220 230 240 250
RILKEDILSF LAKQTGAILP PSPKAEIIAP LSKSETVPTA PKDKARKIPI
260 270 280 290 300
PISRPVVFSG KDKTEPITGF HKAMVKTMSA ALKIPHFGYC DEIDLTHLVQ
310 320 330 340 350
LREELKPLAQ SRGVKLSFMP FFIKAASLGL LQYPILNASL DEGCQNVTYK
360 370 380 390 400
ASHNIGVAMD TEQGLIVPNV KNVQVSSIFE IASELNRLQA LGSASQLGTN
410 420 430 440 450
DLTGGTFTLS NIGTIGGTYA KAVILPPEVA IGALGKIQVL PRFNGKGEVF
460 470 480 490
KAQIMNVSWS ADHRIIDGAT MARFSNLWKS YLENPALMLL DLK
Length:493
Mass (Da):53,998
Last modified:June 1, 2001 - v1
Checksum:i196C1B38EA476F1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB035085 mRNA. Translation: BAB32667.1.
RefSeqiNP_989987.1. NM_204656.1.
UniGeneiGga.187.

Genome annotation databases

GeneIDi395374.
KEGGigga:395374.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB035085 mRNA. Translation: BAB32667.1.
RefSeqiNP_989987.1. NM_204656.1.
UniGeneiGga.187.

3D structure databases

ProteinModelPortaliQ98UJ6.
SMRiQ98UJ6. Positions 62-144, 165-222, 260-493.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000008453.

Proteomic databases

PaxDbiQ98UJ6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi395374.
KEGGigga:395374.

Organism-specific databases

CTDi1629.

Phylogenomic databases

eggNOGiKOG0558. Eukaryota.
COG0508. LUCA.
HOGENOMiHOG000281564.
HOVERGENiHBG104085.
KOiK09699.
PhylomeDBiQ98UJ6.

Enzyme and pathway databases

BRENDAi2.3.1.168. 1306.

Family and domain databases

Gene3Di3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR015761. BCKDC_E2.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR011053. Single_hybrid_motif.
[Graphical view]
PANTHERiPTHR23151:SF71. PTHR23151:SF71. 2 hits.
PfamiPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMiSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ98UJ6_CHICK
AccessioniPrimary (citable) accession number: Q98UJ6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.