Q98TC3 (Q98TC3_SERQU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Protein kinase raf 1 EMBL BAB39747.3

Gene names

Name:

cRAF EMBL BAB39747.3

Organism

Seriola quinqueradiata (Five-ray yellowtail) EMBL BAB39747.3

Taxonomic identifier

8161 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Euteleostei › Neognathi › Neoteleostei › Eurypterygii › Ctenosquamata › Acanthomorpha › Euacanthomorpha › Holacanthopterygii › Acanthopterygii › Euacanthopterygii › Percomorpha › Perciformes › Carangoidei › Carangidae › Seriola

Protein attributes

Sequence length	635 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein. SAAS SAAS020454
Sequence similarities	Belongs to the protein kinase superfamily. RuleBase RU000305 Contains 1 protein kinase domain. SAAS SAAS020454

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS020454 Metal-binding SAAS SAAS020454 Nucleotide-binding Zinc SAAS SAAS020454
Molecular function	Kinase Serine/threonine-protein kinase RuleBase RU000305 SAAS SAAS020454 Transferase
Gene Ontology (GO)
Biological_process	intracellular signal transduction Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW receptor signaling protein activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q98TC3 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: A92D0CE8D855DF5B	FASTA	635	71,690
	10 20 30 40 50 60 MEHLQGAWKT LSNGFGMKDS AFEGPCLSPT MVQGFPCQRR SSDDSKMPDS KTSSTIRVYL 70 80 90 100 110 120 PNQQRTVVNV RPGMTLHNCL IKALKVRGLQ PQCCAVFRLH PGQRSKKLRM DWNTDSTSLI 130 140 150 160 170 180 GQELLVEVLD HVPLTTHNFV RKTYLKLAFC DICQKFLLNG FRCQTCGYKF HEHCSTKVPT 190 200 210 220 230 240 MCVDWSNIRQ LLLCPTPGES GAPSLPPLTS RRMRESLTRF PSSAHRYSTP HAFNYTTPYP 250 260 270 280 290 300 PTGGGLSQRQ RSTSTPNVHM VSTTLPVDSS VIEDAMRDHD SAGSSPSQSP TGWSQSKAPA 310 320 330 340 350 360 PAQRERAPSF NTHEKNKIRP RDKRDSSYYW EIEASEVYLN SRIGSGSFGT VYKGKWHGDV 370 380 390 400 410 420 AVKILKVTDP TPEQFQAFRN EVAVLRKTRH VNILLFMGYM TKDNLAIVTQ WCEGSSLYKH 430 440 450 460 470 480 IHVLETNFKM IQLIDIARQT AQGMDYLHAK NIIHRDMKSN NIFLHEGLTV KIGDFGLATV 490 500 510 520 530 540 KARWSGSHQV EQPSGSILWM APEVIRMQDN NPYSFQSDVY SYGIVLFELM TGELPYSQIA 550 560 570 580 590 600 NRDQIIFMVG RGYLSPDLSK LYKNCPKAMK RLVADCIKKS KDERPLFPQI LSSIELLQHA 610 620 630 LPKINRSASE PSLHRASHTE DINACTLTST RLPVF

References

[1]	"A conserved gene antisense to the proto-oncogene c-RAF encodes a multi-zinc-finger protein, MAKORIN2." Gray T.A., Azama K., Whitmore K.L., Min A., Abe S., Nicholls R.D. Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Gill EMBL BAB39747.3.
[2]	Doi M., Abe S. Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Gill EMBL BAB39747.3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB057654 mRNA. Translation: BAB39747.3.
3D structure databases
HSSP	HSSP built from PDB template 1FAR based on UniProtKB P04049.
ProteinModelPortal	Q98TC3.
SMR	Q98TC3. Positions 53-130, 134-185, 330-603.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG001886.
Family and domain databases
InterPro	IPR020454. DAG/PE-bd. IPR011009. Kinase-like_dom. IPR002219. Prot_Kinase_C-like_PE/DAG-bd. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR003116. Raf-like_ras-bd. IPR001245. Ser-Thr/Tyr_kinase_cat_dom. IPR008271. Ser/Thr_kinase_AS. [Graphical view]
Pfam	PF00130. C1_1. 1 hit. PF07714. Pkinase_Tyr. 1 hit. PF02196. RBD. 1 hit. [Graphical view]
PRINTS	PR00008. DAGPEDOMAIN.
SMART	SM00109. C1. 1 hit. SM00455. RBD. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. PS50898. RBD. 1 hit. PS00479. ZF_DAG_PE_1. 1 hit. PS50081. ZF_DAG_PE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q98TC3_SERQU

Accession

Primary (citable) accession number: Q98TC3

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	April 3, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)