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Q98SV0 (SELPB_DANRE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Selenoprotein Pb

Short name=zSelPb
Gene names
Name:sepp1b
OrganismDanio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome]
Taxonomic identifier7955 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Might be responsible for some of the extracellular antioxidant defense properties of selenium. UniProtKB P49908

Subcellular location

Secreted By similarity UniProtKB P49908.

Ontologies

Keywords
   Cellular componentSecreted
   Coding sequence diversitySelenocysteine
   DomainSignal
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionselenium binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 265247Selenoprotein Pb
PRO_0000022301

Regions

Compositional bias216 – 26449His-rich

Amino acid modifications

Non-standard residue641Selenocysteine
Glycosylation281N-linked (GlcNAc...) Potential
Glycosylation881N-linked (GlcNAc...) Potential
Glycosylation1781N-linked (GlcNAc...) Potential
Glycosylation1841N-linked (GlcNAc...) Potential
Glycosylation2071N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q98SV0 [UniParc].

Last modified February 26, 2008. Version 3.
Checksum: D858FC5CD7EDEB13

FASTA26530,040
        10         20         30         40         50         60 
MQALWPLLLS ALPALLGASS LFVEKESNGS RICKPAPQWE IDGKTPMKEL LGNVVVVALL 

        70         80         90        100        110        120 
KASUHFCLTQ AARLGDLRDK LANGGLTNIS FMVVNEQDSQ SRAMYWELKR RTAQDIPVYQ 

       130        140        150        160        170        180 
QSPLQNDVWE ILEGDKDDFL VYDRCGYLTF HIVLPFSFLH YPYIEAAIRA TYHKNMCNCS 

       190        200        210        220        230        240 
LNANFSISES SDSTKNDPAG ENNQRPNSTE PVTAAHHHHH QQHEPHHHHH NPYPNSHKKS 

       250        260 
GDSDVTGKPK EPPHHSHQEH VHNHR 

« Hide

References

[1]"Selenium metabolism in zebrafish: multiplicity of selenoprotein genes and expression of a protein containing 17 selenocysteine residues."
Kryukov G.V., Gladyshev V.N.
Genes Cells 5:1049-1060(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF322072 mRNA. Translation: AAG53689.1.
UniGeneDr.8516.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

ZFINZDB-GENE-030311-2. sepp1b.

Phylogenomic databases

eggNOGNOG78314.
HOVERGENHBG056814.
PhylomeDBQ98SV0.

Family and domain databases

Gene3D3.40.30.10. 1 hit.
InterProIPR007671. Selenoprotein-P_N.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF04592. SelP_N. 1 hit.
[Graphical view]
SUPFAMSSF52833. SSF52833. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSELPB_DANRE
AccessionPrimary (citable) accession number: Q98SV0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: February 26, 2008
Last modified: April 16, 2014
This is version 68 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program