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Q98SV0

- SELPB_DANRE

UniProt

Q98SV0 - SELPB_DANRE

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Protein

Selenoprotein Pb

Gene
sepp1b
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Might be responsible for some of the extracellular antioxidant defense properties of selenium.By similarity

GO - Molecular functioni

  1. selenium binding Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Selenoprotein Pb
Short name:
zSelPb
Gene namesi
Name:sepp1b
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Unplaced

Organism-specific databases

ZFINiZDB-GENE-030311-2. sepp1b.

Subcellular locationi

Secreted By similarity By similarity

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818 Reviewed predictionAdd
BLAST
Chaini19 – 265247Selenoprotein PbPRO_0000022301Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi28 – 281N-linked (GlcNAc...) Reviewed prediction
Glycosylationi88 – 881N-linked (GlcNAc...) Reviewed prediction
Glycosylationi178 – 1781N-linked (GlcNAc...) Reviewed prediction
Glycosylationi184 – 1841N-linked (GlcNAc...) Reviewed prediction
Glycosylationi207 – 2071N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi216 – 26449His-richAdd
BLAST

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG78314.
HOVERGENiHBG056814.
PhylomeDBiQ98SV0.

Family and domain databases

Gene3Di3.40.30.10. 1 hit.
InterProiIPR007671. Selenoprotein-P_N.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF04592. SelP_N. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q98SV0-1 [UniParc]FASTAAdd to Basket

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MQALWPLLLS ALPALLGASS LFVEKESNGS RICKPAPQWE IDGKTPMKEL    50
LGNVVVVALL KASUHFCLTQ AARLGDLRDK LANGGLTNIS FMVVNEQDSQ 100
SRAMYWELKR RTAQDIPVYQ QSPLQNDVWE ILEGDKDDFL VYDRCGYLTF 150
HIVLPFSFLH YPYIEAAIRA TYHKNMCNCS LNANFSISES SDSTKNDPAG 200
ENNQRPNSTE PVTAAHHHHH QQHEPHHHHH NPYPNSHKKS GDSDVTGKPK 250
EPPHHSHQEH VHNHR 265
Length:265
Mass (Da):30,040
Last modified:February 26, 2008 - v3
Checksum:iD858FC5CD7EDEB13
GO

Non-standard residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-standard residuei64 – 641Selenocysteine

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF322072 mRNA. Translation: AAG53689.1.
UniGeneiDr.8516.

Keywords - Coding sequence diversityi

Selenocysteine

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF322072 mRNA. Translation: AAG53689.1 .
UniGenei Dr.8516.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

ZFINi ZDB-GENE-030311-2. sepp1b.

Phylogenomic databases

eggNOGi NOG78314.
HOVERGENi HBG056814.
PhylomeDBi Q98SV0.

Family and domain databases

Gene3Di 3.40.30.10. 1 hit.
InterProi IPR007671. Selenoprotein-P_N.
IPR012336. Thioredoxin-like_fold.
[Graphical view ]
Pfami PF04592. SelP_N. 1 hit.
[Graphical view ]
SUPFAMi SSF52833. SSF52833. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Selenium metabolism in zebrafish: multiplicity of selenoprotein genes and expression of a protein containing 17 selenocysteine residues."
    Kryukov G.V., Gladyshev V.N.
    Genes Cells 5:1049-1060(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiSELPB_DANRE
AccessioniPrimary (citable) accession number: Q98SV0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: February 26, 2008
Last modified: April 16, 2014
This is version 68 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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