Q98SN1 (Q98SN1_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Gli2 EMBL AAK27699.1

Gene names

Name:	gli2a ZFIN ZDB-GENE-990706-8
Synonyms:	gli2 ZFIN ZDB-GENE-990706-8

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL AAK27699.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	1357 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	adenohypophysis morphogenesis Inferred from mutant phenotype. Source: ZFIN blood circulation Inferred from mutant phenotype. Source: ZFIN dorsal/ventral pattern formation Inferred from mutant phenotype. Source: ZFIN embryonic digestive tract morphogenesis Inferred from mutant phenotype. Source: ZFIN endocrine pancreas development Inferred from mutant phenotype. Source: ZFIN floor plate formation Inferred from mutant phenotype. Source: ZFIN glomerulus development Inferred from mutant phenotype. Source: ZFIN motor axon guidance Inferred from mutant phenotype. Source: ZFIN muscle cell fate specification Inferred from mutant phenotype. Source: ZFIN muscle organ development Inferred from mutant phenotype. Source: ZFIN optic nerve formation Inferred from mutant phenotype. Source: ZFIN post-embryonic foregut morphogenesis Inferred from mutant phenotype. Source: ZFIN regulation of neurogenesis Inferred from mutant phenotype. Source: ZFIN retinal ganglion cell axon guidance Inferred from mutant phenotype. Source: ZFIN somatic motor neuron differentiation Inferred from mutant phenotype. Source: ZFIN somitogenesis Inferred from mutant phenotype. Source: ZFIN striated muscle cell development Inferred from mutant phenotype. Source: ZFIN
Cellular component	nonmotile primary cilium Inferred from direct assay. Source: ZFIN nucleus Inferred from direct assay. Source: ZFIN
Molecular function	nucleic acid binding Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAK27699.1

Sequences

	Sequence		Length	Mass (Da)
	Q98SN1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: FE579FCA168E149A	FASTA	1,357	147,671
	10 20 30 40 50 60 ISDISLIRLS PHAAATGESP FNPPHPYVNP HMEHYLRSVH SSPTLSMISA ARGLSPAELT 70 80 90 100 110 120 HEHLKERSLF GLPPPPPGAN PSEYYHLIAS HRSPYGDLLM QTGAAAAHLP DYMSPVDMSR 130 140 150 160 170 180 FPSPRLTPRV SRKRALSISP VSDASIDLQT MIRTSPNSLV AYINNSRSSS AASSSYGHLS 190 200 210 220 230 240 VGAISPSFTF PHPITPVAYH QLLSQQRGLN AFGHTPPLLQ PSPALSSRQQ TLVAAAALNN 250 260 270 280 290 300 TTSSSTSSST ADTSTESSQN AGGDPAVSST VNPMIFKRSK VKTEAEGPHP ISPGSQDHLE 310 320 330 340 350 360 LREELDKDEC KQEPEAVYET NCHWEGCAKE YDTQDQLVHH ISNDHIHGEK KEFVCRWVEC 370 380 390 400 410 420 SREQKPFKAQ YMLVVHMRRH TGEKPHKCTF EGCSKAYSRL ENLKTHLRSH TGEKPYVCEH 430 440 450 460 470 480 EGCNKAFSNA SDRAKHQNRT HSNEKPYVCK IPGCTKRYTD PSSLRKHVKT VHGPEAHVTK 490 500 510 520 530 540 KQRGDAPPKP HPPKGNGENE AHTKHVRGRT DGSGEANSTT RGVEDCQHVK TIKTENTVMY 550 560 570 580 590 600 QSSPGGQSSC SSEPSPLGSA TNNDSGVEMA MHSGGSLGDL SALDDTPVVD STGSPGTSAG 610 620 630 640 650 660 VGLQLRKNRA GLLQLEHIKK EKLKTVRDSC SWANAPPQVR NTKLPPIPSI DSLLDAPNMG 670 680 690 700 710 720 TQMSVPPTQH LGDLSSYEMT MLNQLHERRD SSTSTMSSAY ISRRSSGISP CYSSRRSSEA 730 740 750 760 770 780 SQFGVRNNNV SSADSYDPIS TDLSRRSSEA SQCGGTGGLP SLLNLTPAQH YSLKAKYAAA 790 800 810 820 830 840 TGGAPPTPLP NMDRMSLKTR MAMYNDSQDS SAHLHHAQGV VNSRRCSDTG YGAPGMMPHE 850 860 870 880 890 900 VPANLPRRAS DPVRRTTLDP LSLPRVQRFN SISNMNLSRL PAYDRRAFNM QNNTWSDGSL 910 920 930 940 950 960 HRHPFSQRPP SISENILMEN MATDGGDQQG DDLVLPDDMV QYLRSQNGNS NHDSGISVNG 970 980 990 1000 1010 1020 GHALEFHGNM TSQQQQFYGQ RRMGMAGING SHVEPVPEQI ADPQGMNKNN MPVQWNEVSS 1030 1040 1050 1060 1070 1080 GSADAVSRVP KQQQQQLRGN LTVVQQKQNF GSYQGFGSNQ QIVPMSQNLA SLQQAYPQRN 1090 1100 1110 1120 1130 1140 IQRMNTVQQF RQSISNPCQN IGEQVNRQDL SYNSNQRLIC NSMGPPNGRV VQNQELQNYR 1150 1160 1170 1180 1190 1200 SNLMHMNNIN QQNYVPLTQT AIQNAGRGLI QPRPPSEPKP LNRQHSGSGM VQPNGCSLSN 1210 1220 1230 1240 1250 1260 VNSSEASPKR PGEVGQHSNG NGTMYYSGEI HMLDNGIDYG SPMSPCTNQA PVASVSTMAS 1270 1280 1290 1300 1310 1320 PGVNQVTSTV DSTQSLDHTQ IDFDAMLDDG DHSSLMSGTL SPGLLQSISQ NSSRLTTPRN 1330 1340 1350 SVTLASVPAG IGNMAIGDMS SMLTALAEES KFLNMMA

References

[1]	"Gli2 mediation of hedgehog signals in slow muscle induction in zebrafish." Du S.J., Dienhart M. Differentiation 67:84-91(2001) [PubMed: 11428131] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Du S., Dienhart M. Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF348156 mRNA. Translation: AAK27699.1.
IPI	IPI00510973.
UniGene	Dr.8091.
3D structure databases
HSSP	HSSP built from PDB template 2GLI based on UniProtKB P08151.
ProteinModelPortal	Q98SN1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q98SN1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
ZFIN	ZDB-GENE-990706-8. gli2a.
Phylogenomic databases
eggNOG	fiNOG12193.
GeneTree	ENSGT00600000084058.
HOVERGEN	HBG005844.
InParanoid	Q98SN1.
Gene expression databases
ArrayExpress	Q98SN1.
Bgee	Q98SN1.
Family and domain databases
InterPro	IPR007087. Znf_C2H2. IPR015880. Znf_C2H2-like. IPR013087. Znf_C2H2/integrase_DNA-bd. [Graphical view]
Gene3D	G3DSA:3.30.160.60. Znf_C2H2/integrase_DNA-bd. 4 hits.
Pfam	PF00096. zf-C2H2. 4 hits. [Graphical view]
SMART	SM00355. ZnF_C2H2. 5 hits. [Graphical view]
PROSITE	PS00028. ZINC_FINGER_C2H2_1. 4 hits. PS50157. ZINC_FINGER_C2H2_2. 4 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q98SN1_DANRE

Accession

Primary (citable) accession number: Q98SN1

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	October 19, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)