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Protein

Translationally-controlled tumor protein homolog

Gene

tpt1

Organism
Labeo rohita (Indian major carp)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in calcium binding and microtubule stabilization.By similarity

Keywords - Ligandi

Calcium

Names & Taxonomyi

Protein namesi
Recommended name:
Translationally-controlled tumor protein homolog
Short name:
TCTP
Gene namesi
Name:tpt1
OrganismiLabeo rohita (Indian major carp)
Taxonomic identifieri84645 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeLabeo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 171171Translationally-controlled tumor protein homologPRO_0000211275Add
BLAST

Proteomic databases

PRIDEiQ98SJ7.

Structurei

3D structure databases

ProteinModelPortaliQ98SJ7.
SMRiQ98SJ7. Positions 1-171.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TCTP family.Curated

Phylogenomic databases

HOVERGENiHBG002282.

Family and domain databases

Gene3Di2.170.150.10. 1 hit.
InterProiIPR011057. Mss4-like.
IPR011323. Mss4/transl-control_tumor.
IPR018103. Translation_control_tumour_CS.
IPR018105. Translational_control_tumour_p.
[Graphical view]
PANTHERiPTHR11991. PTHR11991. 1 hit.
PfamiPF00838. TCTP. 1 hit.
[Graphical view]
PRINTSiPR01653. TCTPROTEIN.
SUPFAMiSSF51316. SSF51316. 1 hit.
PROSITEiPS01002. TCTP_1. 1 hit.
PS01003. TCTP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q98SJ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIIYKDIITG DEMFSDIYKI KESENGMMIE VEGKMISRAE GEIDDALIGG
60 70 80 90 100
NASAEVQDEG CESTTVSGVD IVLNHKLQET SYDKKSYTAY IKDYMKAVKA
110 120 130 140 150
KLQEVAPDRV DPFMANAPAE VKKILGNIKN FQFFTGESMN PDGMIGLLDF
160 170
REDGVTPYML FFKDGLEIEK C
Length:171
Mass (Da):19,123
Last modified:June 1, 2001 - v1
Checksum:iE055B62771B424A9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY028419 mRNA. Translation: AAK27316.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY028419 mRNA. Translation: AAK27316.1.

3D structure databases

ProteinModelPortaliQ98SJ7.
SMRiQ98SJ7. Positions 1-171.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ98SJ7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG002282.

Family and domain databases

Gene3Di2.170.150.10. 1 hit.
InterProiIPR011057. Mss4-like.
IPR011323. Mss4/transl-control_tumor.
IPR018103. Translation_control_tumour_CS.
IPR018105. Translational_control_tumour_p.
[Graphical view]
PANTHERiPTHR11991. PTHR11991. 1 hit.
PfamiPF00838. TCTP. 1 hit.
[Graphical view]
PRINTSiPR01653. TCTPROTEIN.
SUPFAMiSSF51316. SSF51316. 1 hit.
PROSITEiPS01002. TCTP_1. 1 hit.
PS01003. TCTP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Labeo rohita translationally controlled tumor protein."
    Venugopal T., Saral M.V., Pandian T.J., Mathavan S.
    Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiTCTP_LABRO
AccessioniPrimary (citable) accession number: Q98SJ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: June 1, 2001
Last modified: October 14, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.