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Protein
Submitted name:

U2 small nuclear RNA auxiliary factor 1

Gene

U2AF1

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri12 – 40C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri149 – 176C3H1-typePROSITE-ProRule annotationAdd BLAST28

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-GGA-109688 Cleavage of Growing Transcript in the Termination Region
R-GGA-72163 mRNA Splicing - Major Pathway
R-GGA-72187 mRNA 3'-end processing

Names & Taxonomyi

Protein namesi
Submitted name:
U2 small nuclear RNA auxiliary factor 1Imported
Submitted name:
U2snRNP auxiliary factor small subunitImported
Gene namesi
Name:U2AF1Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSGALG00000016198
ExpressionAtlasiQ98SE2 baseline and differential

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000026067

Structurei

3D structure databases

SMRiQ98SE2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 40C3H1-typeInterPro annotationAdd BLAST29
Domaini65 – 147RRMInterPro annotationAdd BLAST83
Domaini149 – 176C3H1-typeInterPro annotationAdd BLAST28

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri12 – 40C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri149 – 176C3H1-typePROSITE-ProRule annotationAdd BLAST28

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2202 Eukaryota
ENOG410Z5PX LUCA
GeneTreeiENSGT00530000063193
HOGENOMiHOG000178619
HOVERGENiHBG054605
KOiK12836
OMAiMHLRLAS
OrthoDBiEOG091G0CUI
TreeFamiTF300143

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR003954 RRM_dom_euk
IPR009145 U2AF_small
IPR000571 Znf_CCCH
PANTHERiPTHR12620 PTHR12620, 1 hit
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
PF00642 zf-CCCH, 2 hits
PRINTSiPR01848 U2AUXFACTOR
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SM00361 RRM_1, 1 hit
SM00356 ZnF_C3H1, 2 hits
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit
PS50103 ZF_C3H1, 2 hits

Sequencei

Sequence statusi: Complete.

Q98SE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEYLASIFG TEKDKVNCSF YFKIGACRHG DRCSRLHNKP TFSQTIALLN
60 70 80 90 100
IYRNPQNSSQ SADGLRCAVS DVEMQEHYDE FFEEVFTEME EKYGEVEEMN
110 120 130 140 150
VCDNLGDHLV GNVYVKFRRE EDAEKAVIDL NNRWFNGQPI HAELSPVTDF
160 170 180 190 200
REACCRQYEM GECTRGGFCN FMHLKPISRE LRRELYGRRR KKHRSRSRSR
210 220 230
ERRSRSRDRG RGGGGGGGGG RERDRRRSRD RERSGRF
Length:237
Mass (Da):27,701
Last modified:June 1, 2001 - v1
Checksum:iD3705CFC4A4D36A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000298 Genomic DNA No translation available.
AJ291762 Genomic DNA Translation: CAC33541.1
AJ291763 mRNA Translation: CAC33542.1
AJ291764 mRNA Translation: CAC33543.1
RefSeqiNP_989986.2, NM_204655.2
UniGeneiGga.4951

Genome annotation databases

EnsembliENSGALT00000026115; ENSGALP00000026067; ENSGALG00000016198
GeneIDi395370
KEGGigga:395370

Similar proteinsi

Entry informationi

Entry nameiQ98SE2_CHICK
AccessioniPrimary (citable) accession number: Q98SE2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: May 23, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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