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Protein
Submitted name:

U2 small nuclear RNA auxiliary factor 1

Gene

U2AF1

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri12 – 40C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri149 – 176C3H1-typePROSITE-ProRule annotationAdd BLAST28

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-GGA-109688. Cleavage of Growing Transcript in the Termination Region.
R-GGA-72163. mRNA Splicing - Major Pathway.
R-GGA-72187. mRNA 3'-end processing.

Names & Taxonomyi

Protein namesi
Submitted name:
U2 small nuclear RNA auxiliary factor 1Imported
Submitted name:
U2snRNP auxiliary factor small subunitImported
Gene namesi
Name:U2AF1Imported
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSGALG00000016198.
ExpressionAtlasiQ98SE2. baseline and differential.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000026067.

Structurei

3D structure databases

SMRiQ98SE2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 40C3H1-typeInterPro annotationAdd BLAST29
Domaini65 – 147RRMInterPro annotationAdd BLAST83
Domaini149 – 176C3H1-typeInterPro annotationAdd BLAST28

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri12 – 40C3H1-typePROSITE-ProRule annotationAdd BLAST29
Zinc fingeri149 – 176C3H1-typePROSITE-ProRule annotationAdd BLAST28

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2202. Eukaryota.
ENOG410Z5PX. LUCA.
GeneTreeiENSGT00530000063193.
HOGENOMiHOG000178619.
HOVERGENiHBG054605.
KOiK12836.
OMAiMHLRLAS.
OrthoDBiEOG091G0CUI.
TreeFamiTF300143.

Family and domain databases

Gene3Di4.10.1000.10. 1 hit.
InterProiView protein in InterPro
IPR035979. RBD_domain_sf.
IPR000504. RRM_dom.
IPR003954. RRM_dom_euk.
IPR009145. U2AF_small.
IPR000571. Znf_CCCH.
IPR036855. Znf_CCCH_sf.
PANTHERiPTHR12620. PTHR12620. 1 hit.
PfamiView protein in Pfam
PF00076. RRM_1. 1 hit.
PF00642. zf-CCCH. 2 hits.
PRINTSiPR01848. U2AUXFACTOR.
SMARTiView protein in SMART
SM00360. RRM. 1 hit.
SM00361. RRM_1. 1 hit.
SM00356. ZnF_C3H1. 2 hits.
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiView protein in PROSITE
PS50102. RRM. 1 hit.
PS50103. ZF_C3H1. 2 hits.

Sequencei

Sequence statusi: Complete.

Q98SE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEYLASIFG TEKDKVNCSF YFKIGACRHG DRCSRLHNKP TFSQTIALLN
60 70 80 90 100
IYRNPQNSSQ SADGLRCAVS DVEMQEHYDE FFEEVFTEME EKYGEVEEMN
110 120 130 140 150
VCDNLGDHLV GNVYVKFRRE EDAEKAVIDL NNRWFNGQPI HAELSPVTDF
160 170 180 190 200
REACCRQYEM GECTRGGFCN FMHLKPISRE LRRELYGRRR KKHRSRSRSR
210 220 230
ERRSRSRDRG RGGGGGGGGG RERDRRRSRD RERSGRF
Length:237
Mass (Da):27,701
Last modified:June 1, 2001 - v1
Checksum:iD3705CFC4A4D36A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000298 Genomic DNA. No translation available.
AJ291762 Genomic DNA. Translation: CAC33541.1.
AJ291763 mRNA. Translation: CAC33542.1.
AJ291764 mRNA. Translation: CAC33543.1.
RefSeqiNP_989986.2. NM_204655.2.
UniGeneiGga.4951.

Genome annotation databases

EnsembliENSGALT00000026115; ENSGALP00000026067; ENSGALG00000016198.
GeneIDi395370.
KEGGigga:395370.

Similar proteinsi

Entry informationi

Entry nameiQ98SE2_CHICK
AccessioniPrimary (citable) accession number: Q98SE2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: October 25, 2017
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported