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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Mycoplasma pulmonis (strain UAB CTIP)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei281Proton donorBy similarity1
Active sitei302By similarity1
Active sitei417By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processGluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciMPUL272635:G1GT6-130-MONOMER
UniPathwayiUPA00109; UER00181

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:MYPU_1310
OrganismiMycoplasma pulmonis (strain UAB CTIP)
Taxonomic identifieri272635 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000000528 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001806871 – 427Glucose-6-phosphate isomeraseAdd BLAST427

Proteomic databases

PRIDEiQ98R79

Interactioni

Protein-protein interaction databases

STRINGi272635.MYPU_1310

Structurei

3D structure databases

ProteinModelPortaliQ98R79
SMRiQ98R79
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Phylogenomic databases

eggNOGiENOG4107QYV Bacteria
COG0166 LUCA
HOGENOMiHOG000100403
KOiK01810
OMAiSFIIPDD
OrthoDBiPOG091H0EIM

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q98R79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRIRLNLQN AINEEKLKEY VSEVEQINTK MNNLSLEGFE YLGWKDLPEN
60 70 80 90 100
INKNEIDKII ETANFFKKEG IEVLVVIGIG GSFLGAKSAM DFIQGNYPTK
110 120 130 140 150
KNMEIIFAGT SISSTELTQL LYYVENKKFA INVISKSGTT LEPAIAFREF
160 170 180 190 200
RNLLNSRLGE NNAKRYIVAT TDANKGLLFE MAKEKGYARF VVPDNVGGRF
210 220 230 240 250
SVLTPVGLLP LACAGIDIEK LLEGAKEANA LYKNSNLLEN DAYKYAVARF
260 270 280 290 300
LLQKKFPVEM LVSYEPNHMF LLEWWKQLFG ESEGKQGKGI LPHSAIFTRD
310 320 330 340 350
LHSLGQFIQD GSKIMFETVI WVDKPIFDLK IEKEIEDLDK LNYLTNKSLH
360 370 380 390 400
QINKAAFEAT VEAHTKVGLV PNIILELEDS SEKTLGALFM FFERAVAMSG
410 420
YLLKVNPFNQ PGVEVYKSNL FKILEKK
Length:427
Mass (Da):48,383
Last modified:October 1, 2001 - v1
Checksum:i7E3CA7379C631683
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445563 Genomic DNA Translation: CAC13304.1
PIRiC90528
RefSeqiWP_010924935.1, NC_002771.1

Genome annotation databases

EnsemblBacteriaiCAC13304; CAC13304; CAC13304
KEGGimpu:MYPU_1310

Similar proteinsi

Entry informationi

Entry nameiG6PI_MYCPU
AccessioniPrimary (citable) accession number: Q98R79
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: October 1, 2001
Last modified: February 28, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome