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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Mycoplasma pulmonis (strain UAB CTIP)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei281 – 2811Proton donorBy similarity
Active sitei302 – 3021By similarity
Active sitei417 – 4171By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:MYPU_1310
OrganismiMycoplasma pulmonis (strain UAB CTIP)
Taxonomic identifieri272635 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000528: Chromosome

Organism-specific databases

GenoListiMYPU_1310.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 427427Glucose-6-phosphate isomerasePRO_0000180687Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272635.MYPU_1310.

Structurei

3D structure databases

ProteinModelPortaliQ98R79.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.Curated

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiSFIIPDD.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q98R79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRIRLNLQN AINEEKLKEY VSEVEQINTK MNNLSLEGFE YLGWKDLPEN
60 70 80 90 100
INKNEIDKII ETANFFKKEG IEVLVVIGIG GSFLGAKSAM DFIQGNYPTK
110 120 130 140 150
KNMEIIFAGT SISSTELTQL LYYVENKKFA INVISKSGTT LEPAIAFREF
160 170 180 190 200
RNLLNSRLGE NNAKRYIVAT TDANKGLLFE MAKEKGYARF VVPDNVGGRF
210 220 230 240 250
SVLTPVGLLP LACAGIDIEK LLEGAKEANA LYKNSNLLEN DAYKYAVARF
260 270 280 290 300
LLQKKFPVEM LVSYEPNHMF LLEWWKQLFG ESEGKQGKGI LPHSAIFTRD
310 320 330 340 350
LHSLGQFIQD GSKIMFETVI WVDKPIFDLK IEKEIEDLDK LNYLTNKSLH
360 370 380 390 400
QINKAAFEAT VEAHTKVGLV PNIILELEDS SEKTLGALFM FFERAVAMSG
410 420
YLLKVNPFNQ PGVEVYKSNL FKILEKK
Length:427
Mass (Da):48,383
Last modified:October 1, 2001 - v1
Checksum:i7E3CA7379C631683
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445563 Genomic DNA. Translation: CAC13304.1.
PIRiC90528.
RefSeqiNP_325962.1. NC_002771.1.
WP_010924935.1. NC_002771.1.

Genome annotation databases

EnsemblBacteriaiCAC13304; CAC13304; CAC13304.
GeneIDi911650.
KEGGimpu:MYPU_1310.
PATRICi20023130. VBIMycPul29704_0130.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445563 Genomic DNA. Translation: CAC13304.1.
PIRiC90528.
RefSeqiNP_325962.1. NC_002771.1.
WP_010924935.1. NC_002771.1.

3D structure databases

ProteinModelPortaliQ98R79.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272635.MYPU_1310.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC13304; CAC13304; CAC13304.
GeneIDi911650.
KEGGimpu:MYPU_1310.
PATRICi20023130. VBIMycPul29704_0130.

Organism-specific databases

GenoListiMYPU_1310.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiSFIIPDD.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UAB CTIP.

Entry informationi

Entry nameiG6PI_MYCPU
AccessioniPrimary (citable) accession number: Q98R79
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: October 1, 2001
Last modified: January 7, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.