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Q98QX2 (ACKA_MYCPU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:MYPU_2380
OrganismMycoplasma pulmonis (strain UAB CTIP) [Complete proteome] [HAMAP]
Taxonomic identifier272635 [NCBI]
Taxonomic lineageBacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length393 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 393393Acetate kinase HAMAP MF_00020
PRO_1000089983

Sequences

Sequence LengthMass (Da)Tools
Q98QX2 [UniParc].

Last modified October 1, 2001. Version 1.
Checksum: EAB3358AD46C3D08

FASTA39343,450
        10         20         30         40         50         60 
MKILVINAGS SSIKFALFEK ENLNQIASGI AERIGIENGI ISISFDKKYQ FEIDMKDHLE 

        70         80         90        100        110        120 
AAKKLLELFE QISLIKNADE IELIGFRVVH GGIELNKASK LDQETISIIE KSAKYAPLHN 

       130        140        150        160        170        180 
PGALQAIKAF QLALPKAKLS VNLDTAFHSS IDKINYSYPI NYELAQKLGI RKFGFHGISH 

       190        200        210        220        230        240 
RFITNKLEKI LNKKSVNFVN LHIGNGASLC AVKVSKSIDT SMGFTPLAGI MMGTRSGDID 

       250        260        270        280        290        300 
PSIHEFVCKE ENMSIEEFTS ILNKQSGISG VSQISSDLRD VEEQYAKGNA QAIFALDLYS 

       310        320        330        340        350        360 
QKIADYAAIY LNKIAPQIDA IVFTAGVGEN SAFVRKNVIS RIKIKNIELD EALNSQKVGE 

       370        380        390 
YQLISTKNSE IPVYVIRTNE ELMIASDAKK LNS

« Hide

References

[1]"The complete genome sequence of the murine respiratory pathogen Mycoplasma pulmonis."
Chambaud I., Heilig R., Ferris S., Barbe V., Samson D., Galisson F., Moszer I., Dybvig K., Wroblewski H., Viari A., Rocha E.P.C., Blanchard A.
Nucleic Acids Res. 29:2145-2153(2001) [PubMed: 11353084] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: UAB CTIP.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL445563 Genomic DNA. Translation: CAC13411.1.
PIRF90541.
RefSeqNP_326069.1. NC_002771.1.

3D structure databases

HSSPHSSP built from PDB template 1G99 based on UniProtKB P38502.
ProteinModelPortalQ98QX2.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID911384.
GenomeReviewsGene locus MYPU_2380 in contig AL445566_GR.
KEGGmpu:MYPU_2380.
PATRIC20023362. VBIMycPul29704_0240.

Organism-specific databases

GenoListMYPU_2380.
CMRSearch...

Phylogenomic databases

HOGENOMHBG285863.
OMAAISHIAR.
PhylomeDBQ98QX2.
ProtClustDBPRK07157.

Enzyme and pathway databases

BioCycMPUL272635:MYPU_2380-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_MYCPU
AccessionPrimary (citable) accession number: Q98QX2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: October 1, 2001
Last modified: January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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