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Q98QW4

- PGK_MYCPU

UniProt

Q98QW4 - PGK_MYCPU

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Mycoplasma pulmonis (strain UAB CTIP)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei35 – 351SubstrateBy similarity
Binding sitei118 – 1181SubstrateBy similarity
Binding sitei155 – 1551SubstrateBy similarity
Binding sitei206 – 2061ATPBy similarity
Binding sitei295 – 2951ATP; via carbonyl oxygenBy similarity
Binding sitei334 – 3341ATPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi361 – 3644ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:MYPU_2460
OrganismiMycoplasma pulmonis (strain UAB CTIP)
Taxonomic identifieri272635 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000528: Chromosome

Organism-specific databases

GenoListiMYPU_2460.

Subcellular locationi

Cytoplasm Curated

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 771771Phosphoglycerate kinasePRO_0000145972Add
BLAST

Proteomic databases

PRIDEiQ98QW4.

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi272635.MYPU_2460.

Structurei

3D structure databases

ProteinModelPortaliQ98QW4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 406406Phosphoglycerate kinaseAdd
BLAST
Regioni20 – 223Substrate bindingBy similarity
Regioni58 – 614Substrate bindingBy similarity
Regioni407 – 771365UnknownAdd
BLAST

Sequence similaritiesi

In the N-terminal section; belongs to the phosphoglycerate kinase family.Curated

Phylogenomic databases

eggNOGiCOG0126.
KOiK00927.
OMAiLETSNFE.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q98QW4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKLITDLNL NDKKVLIRLD LNVPLKGKKI TSLKRIEESI PTIKYVQERG
60 70 80 90 100
GKIILLSHLG RVKTKEDKEK KSLSIVVEAL ASLLNSPVKF VDQTRGKKLE
110 120 130 140 150
SAIEKLKPGD VLLIENTRFE DLNNNAESNN DPELGKYWAS LGDVFINDAF
160 170 180 190 200
GTAHRAHASN VGIASNIKES ALGILVQKEV NALWKLMEQQ EKPFVAILGG
210 220 230 240 250
SKVSDKINVL EKIIDKVDRL IIGGAMAYTF LKAQGIGIGD SIYEQDKIEF
260 270 280 290 300
ATEFLKKYNH KIILPIDHAL AKKFKNAKPI FNNENPLEIP QTFIGMDVGP
310 320 330 340 350
KTIELIHKYI KGDTKLGISP AKTIFWNGPM GVTEFEEFQS GSLAVVEAIS
360 370 380 390 400
QLVGAYSVVG GGDSIAIIEK LNAQMLFSHI STGGGASLEF IESKVLPGID
410 420 430 440 450
AIQNYEQTYE QYDSQVQSQD FSQNFDSPLV EETFSQSTSE NFSDFASSTQ
460 470 480 490 500
EHFATSENQN TLINNYENPG FDSQDMFKTE EQNDSTSSFL TSTNPFSSEF
510 520 530 540 550
SNEFKTSDFQ DLKQTQETET QETLIPHTFE YTTDDLRHTL EQYVRETSFQ
560 570 580 590 600
TRESTFPTEE ASFETLEETS FQTLEESFPT QSFEQVEQTS EKNMEVSTEN
610 620 630 640 650
FENASSQTNS FTVSDIPKTT STFEDLETPE TQNTTLEEVA LETSNFEAQN
660 670 680 690 700
LETPNLQTSN FETSNLETSN FETSNFETST FESFNTGNFS TPSSTFEDLD
710 720 730 740 750
LQSATFQTND ESERSTQENF EPTEVIESDL LAMKTTELEQ EITNNTSRDI
760 770
LSEDEVAAPH KKRFWFFGRK R
Length:771
Mass (Da):86,689
Last modified:October 1, 2001 - v1
Checksum:iCFC542BC9071AB98
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445563 Genomic DNA. Translation: CAC13419.1.
PIRiF90542.
RefSeqiNP_326077.1. NC_002771.1.
WP_010925050.1. NC_002771.1.

Genome annotation databases

EnsemblBacteriaiCAC13419; CAC13419; CAC13419.
GeneIDi911410.
KEGGimpu:MYPU_2460.
PATRICi20023380. VBIMycPul29704_0249.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445563 Genomic DNA. Translation: CAC13419.1 .
PIRi F90542.
RefSeqi NP_326077.1. NC_002771.1.
WP_010925050.1. NC_002771.1.

3D structure databases

ProteinModelPortali Q98QW4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272635.MYPU_2460.

Proteomic databases

PRIDEi Q98QW4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAC13419 ; CAC13419 ; CAC13419 .
GeneIDi 911410.
KEGGi mpu:MYPU_2460.
PATRICi 20023380. VBIMycPul29704_0249.

Organism-specific databases

GenoListi MYPU_2460.

Phylogenomic databases

eggNOGi COG0126.
KOi K00927.
OMAi LETSNFE.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UAB CTIP.

Entry informationi

Entry nameiPGK_MYCPU
AccessioniPrimary (citable) accession number: Q98QW4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: October 1, 2001
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3