Q98QJ8 (NANE_MYCPU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative N-acetylmannosamine-6-phosphate 2-epimerase
EC=5.1.3.9

Alternative name(s):
ManNAc-6-P epimerase

Gene names

Name:	nanE
Ordered Locus Names:	MYPU_3630

Organism

Mycoplasma pulmonis (strain UAB CTIP) [Complete proteome] [HAMAP]

Taxonomic identifier

272635 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	228 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) Potential. HAMAP MF_01235
Catalytic activity	N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate. HAMAP MF_01235
Pathway	Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 3/5. HAMAP MF_01235
Sequence similarities	Belongs to the nanE family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	N-acetylmannosamine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	N-acylglucosamine-6-phosphate 2-epimerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 228	228	Putative N-acetylmannosamine-6-phosphate 2-epimerase HAMAP MF_01235		PRO_0000179786

Sequences

	Sequence		Length	Mass (Da)
	Q98QJ8 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 466A29B2CA218D7A	FASTA	228	25,573
	10 20 30 40 50 60 MFEKKLFFVS CQALKGEALY GKDIVVKLAK AAIQGGAQGL RTSQIKNIKA LIRANFNVPI 70 80 90 100 110 120 IGIIKQNYPN SDVYISPTLK EMKKLIKTGV QIIAIDATLR KRPKESLNQI VDYFFKHKKS 130 140 150 160 170 180 HQLLMADCSS IEDVNNAIKL NFDIIGTTLR GYTEDTKNFS NTDDNYLFLR QVLKICQQNK 190 200 210 220 KYLIAEGGFN SPQNAKDALD IGANAVVVGS AITRPQFITK MFYEKINS

References

[1]

"The complete genome sequence of the murine respiratory pathogen Mycoplasma pulmonis." Chambaud I., Heilig R., Ferris S., Barbe V., Samson D., Galisson F., Moszer I., Dybvig K., Wroblewski H., Viari A., Rocha E.P.C., Blanchard A. Nucleic Acids Res. 29:2145-2153(2001) [PubMed: 11353084] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: UAB CTIP.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL445564 Genomic DNA. Translation: CAC13536.1.
PIR	C90557.
RefSeq	NP_326194.1. NC_002771.1.
3D structure databases
ProteinModelPortal	Q98QJ8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	911397.
GenomeReviews	Gene locus MYPU_3630 in contig AL445566_GR.
KEGG	mpu:MYPU_3630.
PATRIC	20023634. VBIMycPul29704_0364.
Organism-specific databases
GenoList	MYPU_3630.
CMR	Search...
Phylogenomic databases
HOGENOM	HBG296941.
OMA	AMADCSN.
PhylomeDB	Q98QJ8.
ProtClustDB	PRK01130.
Enzyme and pathway databases
BioCyc	MPUL272635:MYPU_3630-MONOMER.
Family and domain databases
HAMAP	MF_01235. ManNAc6P_epimer. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR007260. NanE. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01788.
Pfam	PF04131. NanE. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NANE_MYCPU

Accession

Primary (citable) accession number: Q98QJ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 28, 2003
Last sequence update:	October 1, 2001
Last modified:	January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program