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Q98QB6 (ATPB2_MYCPU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
ATP synthase subunit beta 2
EC=3.6.3.14
Alternative name(s):
ATP synthase F1 sector subunit beta 2
F-ATPase subunit beta 2
Gene names
Name:atpD2
Ordered Locus Names:MYPU_4500
OrganismMycoplasma pulmonis (strain UAB CTIP) [Complete proteome] [HAMAP]
Taxonomic identifier272635 [NCBI]
Taxonomic lineageBacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length468 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits By similarity. HAMAP MF_01347

Catalytic activity

ATP + H2O + H+(In) = ADP + phosphate + H+(Out). HAMAP MF_01347

Subunit structure

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.

Subcellular location

Cell membrane; Peripheral membrane protein By similarity HAMAP MF_01347.

Sequence similarities

Belongs to the ATPase alpha/beta chains family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 468468ATP synthase subunit beta 2 HAMAP MF_01347
PRO_0000144454

Regions

Nucleotide binding145 – 1528ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q98QB6 [UniParc].

Last modified September 26, 2001. Version 1.
Checksum: E29107C313E52992

FASTA46852,653
        10         20         30         40         50         60 
MGKVKHLWSD VYDVEFSENE LPNIGNILSL QDGKCFLMVE RILSNTLVRA ILIKIGEEQI 

        70         80         90        100        110        120 
KINDIAIDTK ESFNVPVGSA TNGAIFDVLG NLLNEHPGDF KKVEVDSTIS TEKHFNSDNE 

       130        140        150        160        170        180 
IINTGIKIID FFVPIIKGSK IGIFGGAGVG KTIIIKELIF NISRQRDSND VKVFFVGTGE 

       190        200        210        220        230        240 
RTREAKELYD ELVNSSLIKS TSLFISQMNE PSGSRMKILP VGITAAEYAR DSEQKDVLFF 

       250        260        270        280        290        300 
VDNIYRYLQA GRELSFSLGK KPSEAGYQAT LVSDISSVQE RLANSKHGSI TSFQTVFLPM 

       310        320        330        340        350        360 
DDLNDPASVA ILNHLDSSLV LSREIFAEGL FPAIDPLLSN SSLLQEKIVG KRHILLVKRV 

       370        380        390        400        410        420 
KKILHKYKQL EEMIMILGVQ ELEPNNRLIV KKAQQLKNYF SQNLFMASSY TKKPGFFADK 

       430        440        450        460 
EEMLDEIEKI VDGHYIDIPE YKFLYLGSSK KLDQIKANLE KDQKEQEN

« Hide

References

[1]"The complete genome sequence of the murine respiratory pathogen Mycoplasma pulmonis."
Chambaud I., Heilig R., Ferris S., Barbe V., Samson D., Galisson F., Moszer I., Dybvig K., Wroblewski H., Viari A., Rocha E.P.C., Blanchard A.
Nucleic Acids Res. 29:2145-2153(2001) [PubMed: 11353084] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: UAB CTIP.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL445564 Genomic DNA. Translation: CAC13623.1.
PIRB90568.
RefSeqNP_326281.1. NC_002771.1.

3D structure databases

ProteinModelPortalQ98QB6.
ModBaseSearch...

Proteomic databases

PRIDEQ98QB6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID911543.
GenomeReviewsGene locus MYPU_4500 in contig AL445566_GR.
KEGGmpu:MYPU_4500.
PATRIC20023814. VBIMycPul29704_0453.

Organism-specific databases

GenoListMYPU_4500.
CMRSearch...

Phylogenomic databases

HOGENOMHBG565875.
OMAFLMVERI.
PhylomeDBQ98QB6.
ProtClustDBPRK12597.

Enzyme and pathway databases

BioCycMPUL272635:MYPU_4500-MONOMER.

Family and domain databases

HAMAPMF_01347. ATP_synth_beta_bact.
[Tree]
InterProIPR020003. ATPase_a/bsu_AS.
IPR003593. ATPase_AAA+_core.
IPR005722. ATPase_F1-cplx_bsu.
IPR018118. ATPase_F1/A1-cplx_a/bsu_N.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
IPR024034. ATPase_F1_bsu/V1_C.
[Graphical view]
Gene3DG3DSA:1.10.1140.10. G3DSA:1.10.1140.10. 1 hit.
KOK02112.
PfamPF00006. ATP-synt_ab. 1 hit.
PF00306. ATP-synt_ab_C. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF47917. ATPase_a/b_C. 1 hit.
SSF50615. ATPase_a/b_N. 1 hit.
PROSITEPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATPB2_MYCPU
AccessionPrimary (citable) accession number: Q98QB6
Entry history
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: September 26, 2001
Last modified: January 25, 2012
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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