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Protein

Guanylate kinase

Gene

gmk

Organism
Mycoplasma pulmonis (strain UAB CTIP)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi14 – 21ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMPUL272635:G1GT6-701-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:MYPU_6870
OrganismiMycoplasma pulmonis (strain UAB CTIP)
Taxonomic identifieri272635 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000000528 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001705691 – 196Guanylate kinaseAdd BLAST196

Interactioni

Protein-protein interaction databases

STRINGi272635.MYPU_6870

Structurei

3D structure databases

ProteinModelPortaliQ98PN5
SMRiQ98PN5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 191Guanylate kinase-likeUniRule annotationAdd BLAST185

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA Bacteria
COG0194 LUCA
HOGENOMiHOG000037639
KOiK00942
OMAiAGNYYGT
OrthoDBiPOG091H01Q4

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q98PN5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MINIHKRNIV LLVGPSGVGK GTIEKILFES KTLKLSLSRS ATTRKKREGE
60 70 80 90 100
INGIHYFFIS KEEFESKIEN DEFMEWNEHF DNYYGTLLSE ILLIFSQGRI
110 120 130 140 150
PVLEVETYGA KKILQKYKDK KDFNWITIFV DPPSFEELEN RIIKRGTDTK
160 170 180 190
EKIAIRMAKA KEELKDRDLF EFKITNHTPE QAAEEIEKII LKKTMG
Length:196
Mass (Da):22,918
Last modified:October 1, 2001 - v1
Checksum:i6B491B28A7E06ECE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445565 Genomic DNA Translation: CAC13860.1
PIRiG90597
RefSeqiWP_010925488.1, NC_002771.1

Genome annotation databases

EnsemblBacteriaiCAC13860; CAC13860; CAC13860
KEGGimpu:MYPU_6870

Similar proteinsi

Entry informationi

Entry nameiKGUA_MYCPU
AccessioniPrimary (citable) accession number: Q98PN5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2002
Last sequence update: October 1, 2001
Last modified: March 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health