Q98PK2 (EX53_MYCPU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-3' exonuclease
EC=3.1.11.-

Gene names

Name:	polA
Ordered Locus Names:	MYPU_7200

Organism

Mycoplasma pulmonis (strain UAB CTIP) [Complete proteome] [HAMAP]

Taxonomic identifier

272635 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	297 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	5'-3' exonuclease acting preferentially on double-stranded DNA By similarity.
Sequence similarities	Contains 1 5'-3' exonuclease domain.

Ontologies

Keywords
Ligand	DNA-binding
Molecular function	Exonuclease Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: InterPro
Molecular function	5'-3' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 297	297	5'-3' exonuclease		PRO_0000101288

Sequences

	Sequence		Length	Mass (Da)
	Q98PK2 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 02BECA7C4FA1889D	FASTA	297	34,755
	10 20 30 40 50 60 MTKSGSKSEK FLLIDGNYLV HRSYYVSFKF KNNFRSTIYL FFQTIIKIIK NLNPENIFIA 70 80 90 100 110 120 FDEEGGTWRH DLCKEYKSQR SKMEDEFWNI FKAIREILDS INLNSGGFRG HEADDVIATI 130 140 150 160 170 180 TSKFKDENQI YIFSRDKDLL QLIDKNVYIT HDNELKNLIS IENFYQNFQL EPDQIVDFKA 190 200 210 220 230 240 IAGDSSDNLK GIAGIGEKGA KNLLNNFKSL EKIFDSLEST NLISKAQKQK IRDGKEQALF 250 260 270 280 290 LKKIVTLNKE VPMKLEKELF AIKININEEI LEKLDKYDSR YVLKQFEKAL ESDDYLW

References

[1]

"The complete genome sequence of the murine respiratory pathogen Mycoplasma pulmonis." Chambaud I., Heilig R., Ferris S., Barbe V., Samson D., Galisson F., Moszer I., Dybvig K., Wroblewski H., Viari A., Rocha E.P.C., Blanchard A. Nucleic Acids Res. 29:2145-2153(2001) [PubMed: 11353084] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: UAB CTIP.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL445565 Genomic DNA. Translation: CAC13893.1.
PIR	H90601.
RefSeq	NP_326551.1. NC_002771.1.
3D structure databases
ProteinModelPortal	Q98PK2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	911027.
GenomeReviews	Gene locus MYPU_7200 in contig AL445566_GR.
KEGG	mpu:MYPU_7200.
PATRIC	20024398. VBIMycPul29704_0735.
Organism-specific databases
GenoList	MYPU_7200.
CMR	Search...
Phylogenomic databases
HOGENOM	HBG701384.
OMA	HGEKVTI.
PhylomeDB	Q98PK2.
Enzyme and pathway databases
BioCyc	MPUL272635:MYPU_7200-MONOMER.
Family and domain databases
InterPro	IPR020046. 5-3_exonucl_a-hlix_arch_N. IPR020045. 5-3_exonuclease_C. IPR002421. 5-3_exonuclease_N. IPR008918. HhH2. IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif. [Graphical view]
KO	K02335.
Pfam	PF01367. 5_3_exonuc. 1 hit. PF02739. 5_3_exonuc_N. 1 hit. [Graphical view]
SMART	SM00475. 53EXOc. 1 hit. SM00278. HhH1. 1 hit. SM00279. HhH2. 1 hit. [Graphical view]
SUPFAM	SSF47807. 5_3_exo_C. 1 hit.
ProtoNet	Search...

Entry information

Entry name

EX53_MYCPU

Accession

Primary (citable) accession number: Q98PK2

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 16, 2001
Last sequence update:	October 1, 2001
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program