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Q98PH7

- SYW_MYCPU

UniProt

Q98PH7 - SYW_MYCPU

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Protein

Tryptophan--tRNA ligase

Gene

trpS

Organism
Mycoplasma pulmonis (strain UAB CTIP)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-tRNA(Trp).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei203 – 2031ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. tryptophan-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. tryptophanyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Tryptophan--tRNA ligaseUniRule annotation (EC:6.1.1.2UniRule annotation)
Alternative name(s):
Tryptophanyl-tRNA synthetaseUniRule annotation
Short name:
TrpRSUniRule annotation
Gene namesi
Name:trpSUniRule annotation
Ordered Locus Names:MYPU_7450
OrganismiMycoplasma pulmonis (strain UAB CTIP)
Taxonomic identifieri272635 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000528: Chromosome

Organism-specific databases

GenoListiMYPU_7450.

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 332332Tryptophan--tRNA ligasePRO_0000136649Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi272635.MYPU_7450.

Structurei

3D structure databases

ProteinModelPortaliQ98PH7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi12 – 209"HIGH" region
Motifi200 – 2045"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0180.
HOGENOMiHOG000059940.
KOiK01867.
OMAiLLNCYTY.
OrthoDBiEOG686NJQ.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_00140_B. Trp_tRNA_synth_B.
InterProiIPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR024109. Trp-tRNA-ligase_bac-type.
[Graphical view]
PANTHERiPTHR10055. PTHR10055. 1 hit.
PfamiPF00579. tRNA-synt_1b. 1 hit.
[Graphical view]
PRINTSiPR01039. TRNASYNTHTRP.
TIGRFAMsiTIGR00233. trpS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q98PH7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNKKTLVSGI TSTGKLTLGN YIGAIRNFVK LQDEFNMFIF VADLHSLTNE
60 70 80 90 100
IVPSVLRKNI KEIAALYLAC GLDPEKTVLF KQSDVYEHGL MQWILLNQTT
110 120 130 140 150
IGELSRMTQF KDKSSKITHA NNTESIPSGL LTYPTLMAAD ILLYNPNLVP
160 170 180 190 200
VGQDQVQHLE LTRKIARKLN NKYNTKFNEP TTFVPETGAK IMSLTNPTKK
210 220 230 240 250
MSKSSDDING TIFLLEDPEL AYKKIKKSIT DSENKVYHDP SKPGVSNLLE
260 270 280 290 300
IYACLENKSL KEAQEIFKDK NYLELKEGVG NSVKNFLTKL QAKYQENYKR
310 320 330
VDEILNQGKI KAQKVASYNL NNLMKKIGIR DK
Length:332
Mass (Da):37,588
Last modified:October 1, 2001 - v1
Checksum:iC4F6AED7772CF68E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL445565 Genomic DNA. Translation: CAC13918.1.
PIRiA99605.
RefSeqiNP_326576.1. NC_002771.1.
WP_010925546.1. NC_002771.1.

Genome annotation databases

EnsemblBacteriaiCAC13918; CAC13918; CAC13918.
GeneIDi911011.
KEGGimpu:MYPU_7450.
PATRICi20024450. VBIMycPul29704_0761.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL445565 Genomic DNA. Translation: CAC13918.1 .
PIRi A99605.
RefSeqi NP_326576.1. NC_002771.1.
WP_010925546.1. NC_002771.1.

3D structure databases

ProteinModelPortali Q98PH7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272635.MYPU_7450.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAC13918 ; CAC13918 ; CAC13918 .
GeneIDi 911011.
KEGGi mpu:MYPU_7450.
PATRICi 20024450. VBIMycPul29704_0761.

Organism-specific databases

GenoListi MYPU_7450.

Phylogenomic databases

eggNOGi COG0180.
HOGENOMi HOG000059940.
KOi K01867.
OMAi LLNCYTY.
OrthoDBi EOG686NJQ.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
HAMAPi MF_00140_B. Trp_tRNA_synth_B.
InterProi IPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR024109. Trp-tRNA-ligase_bac-type.
[Graphical view ]
PANTHERi PTHR10055. PTHR10055. 1 hit.
Pfami PF00579. tRNA-synt_1b. 1 hit.
[Graphical view ]
PRINTSi PR01039. TRNASYNTHTRP.
TIGRFAMsi TIGR00233. trpS. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: UAB CTIP.

Entry informationi

Entry nameiSYW_MYCPU
AccessioniPrimary (citable) accession number: Q98PH7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2001
Last modified: October 29, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3