Reviewed, UniProtKB/Swiss-Prot Q98PH2 (MTLD_MYCPU)

Names and origin

Protein names

Recommended name:
    Mannitol-1-phosphate 5-dehydrogenase
    EC=1.1.1.17

Gene names

Name:	mtlD
Ordered Locus Names:	MYPU_7500

Organism

Mycoplasma pulmonis [Complete proteome] [HAMAP]

Taxonomic identifier

2107 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	360 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH. HAMAP MF_00196
Sequence similarities	Belongs to the mannitol dehydrogenase family.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro mannitol-1-phosphate 5-dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 360	360	Mannitol-1-phosphate 5-dehydrogenase HAMAP MF_00196		PRO_0000170713
Regions
	Nucleotide binding	6 – 17	12	NAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q98PH2-1 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: E60949DC40914B1D	FASTA	360	42,410
	10 20 30 40 50 60 MKKYKALHFG AGNIGRGLIS DIYMKNNMDF ALVDIDKDLI EKLNKQKSYS IIDFQTNKVF 70 80 90 100 110 120 QISNFKAFSI DQEDEIKKWI EQADFISTSI GWSNLASLKK FFENVKLKEK AQIICFENGY 130 140 150 160 170 180 KISSFFQSIL NIDSNHFVNA SVDKIIPNFK SDSLDVYVES YYEIILEQKN ESQKKLNFVN 190 200 210 220 230 240 YSTDLEAYIN KKLFLVNAIH STIGYLGYLK KYTYINEALN DQQILFKIKR LAKIINEILS 250 260 270 280 290 300 KEYLLFKVDY LNDYLEKNLK RFSIKENQDL ISRVARNPIQ KLSKNERYFL IYNLVKKHNL 310 320 330 340 350 360 EIDILLEIYK SIFYYDNKMD KESSKIQSTI ENKSLAYALK KFSNLDQEDQ EKILKSLAKK

References

[1]

"The complete genome sequence of the murine respiratory pathogen Mycoplasma pulmonis." Chambaud I., Heilig R., Ferris S., Barbe V., Samson D., Galisson F., Moszer I., Dybvig K., Wroblewski H., Viari A., Rocha E.P.C., Blanchard A. Nucleic Acids Res. 29:2145-2153(2001) [PubMed: 11353084] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: UAB CTIP.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL445565 Genomic DNA. Translation: CAC13923.1.
PIR	F90605.
RefSeq	NP_326581.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	910995.
GenomeReviews	Gene locus MYPU_7500 in contig AL445566_GR.
KEGG	mpu:MYPU_7500.
Organism-specific databases
MypuList	MYPU_7500.
CMR	Search...
Phylogenomic databases
HOGENOM	Q98PH2.
OMA	Q98PH2. VDRIVPN.
Enzyme and pathway databases
BioCyc	MPUL272635:MYPU_7500-MON.
BRENDA	1.1.1.17. 274806.
Family and domain databases
HAMAP	MF_00196. [Tree]
InterPro	IPR013328. DH_multihelical. IPR013118. Mannitol_DH_C. IPR000669. Mannitol_DH_core. IPR013131. Mannitol_DH_N. [Graphical view]
Gene3D	G3DSA:1.10.1040.10. Opine_DH. 1 hit.
Pfam	PF01232. Mannitol_dh. 1 hit. PF08125. Mannitol_dh_C. 1 hit. [Graphical view]
PRINTS	PR00084. MTLDHDRGNASE.
PROSITE	PS00974. MANNITOL_DHGENASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MTLD_MYCPU

Accession

Primary (citable) accession number: Q98PH2

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 19, 2002
Last sequence update:	October 1, 2001
Last modified:	June 16, 2009
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)