Q98MY4 (Q98MY4_RHILO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Dihydrolipoyl dehydrogenase RuleBase RU003692
EC=1.8.1.4 RuleBase RU003692

Gene names

Ordered Locus Names:

mlr0388

Organism

Rhizobium loti (strain MAFF303099) (Mesorhizobium loti) [Complete proteome] [HAMAP]

Taxonomic identifier

266835 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Mesorhizobium

Protein attributes

Sequence length	481 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Protein N(6)-(dihydrolipoyl)lysine + NAD+ = protein N(6)-(lipoyl)lysine + NADH. RuleBase RU003692
Cofactor	Binds 1 FAD per subunit By similarity. RuleBase RU003692
Miscellaneous	The active site is a redox-active disulfide bond By similarity. RuleBase RU003692
Sequence similarities	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. RuleBase RU003691

Ontologies

Keywords
Domain	Redox-active center RuleBase RU003691
Ligand	FAD RuleBase RU003691 Flavoprotein RuleBase RU003691 NAD RuleBase RU003692
Molecular function	Oxidoreductase RuleBase RU003691
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	dihydrolipoyl dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q98MY4 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 65CEA1B4B306C0C9	FASTA	481	51,498
	10 20 30 40 50 60 MAENYDVIII GSGPGGYVTA VRSAQLGFKT AIVEREHLGG ICLNWGCIPT KALLRSAEIM 70 80 90 100 110 120 HYSDHLKDYG LKLDGKVSVD TSAVVDRSRK VSLRLNGGVA FLMKKNKVDV IWGEAKLSKP 130 140 150 160 170 180 GEVVVSKTAK TPMEPQPPVP KGVKGEGTYT AKHIILATGA RPRALPGIEP DGKLIWTYFE 190 200 210 220 230 240 AMVPKEMPKS LLVMGSGAIG IEFASFYRTM GADVTVVELL PAVMPVEDAE VSKFAQKQFE 250 260 270 280 290 300 KQGMKIILEA KVTKVEKGAN SVTAHVEMKD GKVEKITADR MISAVGVQGN IENLGLEALG 310 320 330 340 350 360 VKTDRGCIVV DGYGKTNVPG IYAIGDVAGP PMLAHKAEHE GVVCVEKIAG FPGVHAIDKL 370 380 390 400 410 420 KIPGCTYCNP QVASVGLTEA KAKAEGKDIR VGRFQFAANG KAIALGEDQG FIKTIFDKKT 430 440 450 460 470 480 GQLLGAHMVG AEVTELIQGF VVAMNLETTE EELMHTIFPH PTLSEMMKES VLDAYGRALN A

References

[1]

"Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti." Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S., Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y., Nakayama S. , Nakazaki N., Shimpo S., Sugimoto M., Takeuchi C., Yamada M., Tabata S. DNA Res. 7:331-338(2000) [PubMed: 11214968] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MAFF303099.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000012 Genomic DNA. Translation: BAB47979.1.
RefSeq	NP_102193.1. NC_002678.2.
3D structure databases
HSSP	HSSP built from PDB template 1DXL based on UniProtKB P31023.
ProteinModelPortal	Q98MY4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1224856.
GenomeReviews	Gene locus mlr0388 in contig BA000012_GR.
KEGG	mlo:mlr0388.
NMPDR	fig|266835.1.peg.298.
PATRIC	22474772. VBIMesLot2464_0308.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG515043.
OMA	HYMQHAK.
ProtClustDB	PRK06416.
Family and domain databases
InterPro	IPR016156. FAD/NAD-linked_Rdtase_dimer. IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR006258. Lipoamide_DH. IPR004099. Pyr_nucl-diS_OxRdtase_dimer. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR012999. Pyr_OxRdtase_I_AS. IPR001327. Pyr_OxRdtase_NAD-bd_dom. [Graphical view]
Gene3D	G3DSA:3.30.390.30. Pyr_redox_dim. 1 hit.
KO	K00382.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 2 hits. PF02852. Pyr_redox_dim. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR.
SUPFAM	SSF55424. FAD/NAD-linked_reductase_dimer. 1 hit.
TIGRFAMs	TIGR01350. Lipoamide_DH. 1 hit.
PROSITE	PS00076. PYRIDINE_REDOX_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q98MY4_RHILO

Accession

Primary (citable) accession number: Q98MY4

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2001
Last sequence update:	October 1, 2001
Last modified:	January 25, 2012
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)