Q98MC8 (Q98MC8_RHILO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL BAB48185.1

Gene names

Ordered Locus Names:

mll0630

Organism

Rhizobium loti (strain MAFF303099) (Mesorhizobium loti) [Complete proteome] [HAMAP]

Taxonomic identifier

266835 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Mesorhizobium

Protein attributes

Sequence length	390 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q98MC8 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 1711E6239A89CB5A	FASTA	390	42,800
	10 20 30 40 50 60 MADRVLKIAI VAGEESGDLL GADIVRSLRQ ITGREVRLVG LGGRHLGELG LVSPFDAGEI 70 80 90 100 110 120 ALMGFSAVLR DLPRLIRRIG QLAKTIAEEK PDCLVTIDSP DFSLRVARKV RAANPSIPII 130 140 150 160 170 180 HYVCPSVWAW RPGRAVAMKP YVDHILCILP FEVKELDRLG GPPGTYVGHR LTHDVGVLAA 190 200 210 220 230 240 QKAQALPRDL AQDRIKTLLV LPGSRRGEVR RLIEPFGETV SMLRARGHRL RLQLPTVPHV 250 260 270 280 290 300 ADLVKSSVNR WDEKPEIIVD PQRKWQAFGK ADAALIASGT VSLELALAGV PMVSSYRLDP 310 320 330 340 350 360 IARAVAPYLV SVWSALLPNL ISDRALIPEF YNEYVKANNL ARQLEALFAD SGMRAWQKDG 370 380 390 FAEIARRMAT DKPSGEIAAG VVLRHIKKAP

References

[1]

"Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti." Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S., Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y., Nakayama S. , Nakazaki N., Shimpo S., Sugimoto M., Takeuchi C., Yamada M., Tabata S. DNA Res. 7:331-338(2000) [PubMed: 11214968] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MAFF303099.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000012 Genomic DNA. Translation: BAB48185.1.
RefSeq	NP_102399.1. NC_002678.2.
3D structure databases
ProteinModelPortal	Q98MC8.
ModBase	Search...
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1225062.
GenomeReviews	Gene locus mll0630 in contig BA000012_GR.
KEGG	mlo:mll0630.
NMPDR	fig|266835.1.peg.504.
PATRIC	22475176. VBIMesLot2464_0508.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	PINILCY.
ProtClustDB	PRK00025.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q98MC8_RHILO

Accession

Primary (citable) accession number: Q98MC8

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2001
Last sequence update:	October 1, 2001
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)