Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q98LX5

- GLMS_RHILO

UniProt

Q98LX5 - GLMS_RHILO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene

glmS

Organism
Rhizobium loti (strain MAFF303099) (Mesorhizobium loti)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activityUniRule annotation
Active sitei602 – 6021For Fru-6P isomerization activityUniRule annotation

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate biosynthetic process Source: InterPro
  2. glutamine metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

BioCyciMLOT266835:GJ9L-665-MONOMER.

Protein family/group databases

MEROPSiC44.971.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation (EC:2.6.1.16UniRule annotation)
Alternative name(s):
D-fructose-6-phosphate amidotransferaseUniRule annotation
GFATUniRule annotation
Glucosamine-6-phosphate synthaseUniRule annotation
Hexosephosphate aminotransferaseUniRule annotation
L-glutamine--D-fructose-6-phosphate amidotransferaseUniRule annotation
Gene namesi
Name:glmSUniRule annotation
Ordered Locus Names:mll0833
OrganismiRhizobium loti (strain MAFF303099) (Mesorhizobium loti)
Taxonomic identifieri266835 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
ProteomesiUP000000552: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedUniRule annotation
Chaini2 – 607606Glutamine--fructose-6-phosphate aminotransferase [isomerizing]PRO_0000135371Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi266835.mll0833.

Structurei

3D structure databases

ProteinModelPortaliQ98LX5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 217216Glutamine amidotransferase type-2UniRule annotationAdd
BLAST
Domaini283 – 422140SIS 1UniRule annotationAdd
BLAST
Domaini455 – 597143SIS 2UniRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 glutamine amidotransferase type-2 domain.UniRule annotation
Contains 2 SIS domains.UniRule annotation

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiCOG0449.
HOGENOMiHOG000258896.
KOiK00820.
OMAiNTPVERE.
OrthoDBiEOG6KT2Q1.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
HAMAPiMF_00164. GlmS.
InterProiIPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
PfamiPF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01135. glmS. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q98LX5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MCGIVGIVGH SQVAPLIVDA LKRLEYRGYD SAGVATIEHG ELARRRAEGK
60 70 80 90 100
LINLERRLKE EPLDGTIGIG HTRWATHGVP NETNAHPHFS DGVAIVHNGI
110 120 130 140 150
IENFAELRDE LVRDGYAFSS QTDTEVVAHL VARELAKGLK PVEAAHQALK
160 170 180 190 200
RLEGAFALAI MFKGDEDLIV GARNGPPLAV GHGDGEMFLG SDAIALAPFT
210 220 230 240 250
NSITYLEDGD WAVVRRDSVA IFDIDGKKVE RKRQQSLSTS FMVDKGNRRH
260 270 280 290 300
FMEKEIHEQP EVISHTLAHY VDFVSGVSKP LDLPFDFAKI GRLAISACGT
310 320 330 340 350
AYLAGLIGKY WFERYARLPV DIDVASEFRY REMPLSANDA AFFISQSGET
360 370 380 390 400
ADTLASLRYC RKAGMKIGAV VNVRESTMAR ESDVVLPTLA GPEIGVASTK
410 420 430 440 450
AFTCQLSVLA SLAVRAGVAR GVISQEQEKT LVRALSEAPR YANQVLKLEE
460 470 480 490 500
QIERIARELS RYKDVLYLGR DTNFPLAMEG ALKLKEISYI HAEGYAAGEL
510 520 530 540 550
KHGPIALIDE NMPVIVIAPH DRIFEKTVSN MQEVAARGGK IILITDSKGA
560 570 580 590 600
AQVSVKTMET IILPDVPEII SPIIYALPIQ MLAYFAAVFM GTDVDQPRNL

AKSVTVE
Length:607
Mass (Da):66,439
Last modified:January 23, 2007 - v3
Checksum:iFD9A7DE1623F622A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000012 Genomic DNA. Translation: BAB48338.1.
RefSeqiNP_102552.1. NC_002678.2.

Genome annotation databases

EnsemblBacteriaiBAB48338; BAB48338; BAB48338.
GeneIDi1225215.
KEGGimlo:mll0833.
PATRICi22475488. VBIMesLot2464_0663.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000012 Genomic DNA. Translation: BAB48338.1 .
RefSeqi NP_102552.1. NC_002678.2.

3D structure databases

ProteinModelPortali Q98LX5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 266835.mll0833.

Protein family/group databases

MEROPSi C44.971.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB48338 ; BAB48338 ; BAB48338 .
GeneIDi 1225215.
KEGGi mlo:mll0833.
PATRICi 22475488. VBIMesLot2464_0663.

Phylogenomic databases

eggNOGi COG0449.
HOGENOMi HOG000258896.
KOi K00820.
OMAi NTPVERE.
OrthoDBi EOG6KT2Q1.

Enzyme and pathway databases

BioCyci MLOT266835:GJ9L-665-MONOMER.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
HAMAPi MF_00164. GlmS.
InterProi IPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
Pfami PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01135. glmS. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MAFF303099.

Entry informationi

Entry nameiGLMS_RHILO
AccessioniPrimary (citable) accession number: Q98LX5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 73 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3