ID   Q98LH3_RHILO            Unreviewed;       626 AA.
AC   Q98LH3;
DT   01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2001, sequence version 1.
DT   27-MAR-2024, entry version 118.
DE   SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:BAB48490.1};
GN   OrderedLocusNames=mll1022 {ECO:0000313|EMBL:BAB48490.1};
OS   Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)
OS   (Mesorhizobium loti (strain MAFF 303099)).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=266835 {ECO:0000313|EMBL:BAB48490.1, ECO:0000313|Proteomes:UP000000552};
RN   [1] {ECO:0000313|EMBL:BAB48490.1, ECO:0000313|Proteomes:UP000000552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 29417 / CECT 9101 / MAFF 303099
RC   {ECO:0000313|Proteomes:UP000000552};
RX   PubMed=11214968; DOI=10.1093/dnares/7.6.331;
RA   Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y.,
RA   Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y.,
RA   Nakayama S., Nakazaki N., Shimpo S., Sugimoto M., Takeuchi C., Yamada M.,
RA   Tabata S.;
RT   "Complete genome structure of the nitrogen-fixing symbiotic bacterium
RT   Mesorhizobium loti.";
RL   DNA Res. 7:331-338(2000).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000012; BAB48490.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q98LH3; -.
DR   KEGG; mlo:mll1022; -.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG5616; Bacteria.
DR   HOGENOM; CLU_019981_0_0_5; -.
DR   Proteomes; UP000000552; Chromosome.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 3.40.50.10070; TolB, N-terminal domain; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   Pfam; PF14559; TPR_19; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR   PROSITE; PS50005; TPR; 1.
PE   4: Predicted;
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   DOMAIN          9..125
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REPEAT          424..457
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   626 AA;  69267 MW;  8DEC6930401282A9 CRC64;
     MRETRKIAAI LVSDVVGYSR LAGVDEDRIL ARLRALRSDL IDPTIAVHRG RVVKRTGDGS
     LVEFSSVVEA VRCAIEVQNA MLERNAGVPD DRRIEFRIGI HLGDVVQERD GDLMGDGINI
     AARLEGICEP GNICLSEQAY WQVKSRLDIA INDRGAVQLK NIAEPVRVYS LQVGVPTKAK
     PAAPAEPLVL EKFSQPLAPP DNHSIAVLPF INMRGDSEQE FFTDGLTEDI ITDLSNVSGF
     FVIARNSTFA YKGKPTDVRQ ISRDLGVKYI LEGSARRSNK RLRVNVQLIN AGEGGNHVWA
     ERFDREIADI FDVQDEVTRR VVEAISGKLG EKKLVARSRP SNLEAYDLCV RSRGKCNNSR
     SDNREACADL ERAIQIDPNY CEAHSNLAIS LLFGWIIWGE PQEPGRANAL IHAQRAVEID
     PDDSHARRIL GCVQLYERNW DEAKSQFDAA VRLNPNNADA VAWMGELQIY LGDPQAALRA
     CGAALRINPR PPGWYFWIMG IAQISSGHYE EAVASLSREE TYGTGSREHL VPALALAGRV
     PEAQEEARLF LAGNPKWSVS DLVAASPFKS PSDAQPFVAG VWRACWTDGA SKRIEIGKNC
     SVGTIEGIRG DRHYHERSRL AQRSRV
//