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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (Mesorhizobium loti (strain MAFF 303099))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMLOT266835:G1G20-896-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:mll1091
OrganismiMesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (Mesorhizobium loti (strain MAFF 303099))
Taxonomic identifieri266835 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
Proteomesi
  • UP000000552 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515961 – 585Arginine--tRNA ligaseAdd BLAST585

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi266835.mll1091

Structurei

3D structure databases

ProteinModelPortaliQ98LC0
SMRiQ98LC0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi131 – 141"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q98LC0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIFADFTAR VTKAVEALDL KDKDGISPDL SRIAVEPPRD ASHGDLATNA
60 70 80 90 100
AMVLAKPTGQ NPRALAEKLA LALRDDKDVA AAEVAGPGFV NLRLKDGFWQ
110 120 130 140 150
AHLSALLGDG RNYGRSTVGA GRKTNVEYVS ANPTGPMHVG HCRGAVVGDA
160 170 180 190 200
LANLMAFAGY DVTKEYVIND AGGQIDVLGR SVILRYREAL GDEIGEIPPG
210 220 230 240 250
LYPGDYLVPL GQALAKEFGH GLLQMPEDEA LAIVKDRAID AMMAMIRDDL
260 270 280 290 300
ALLNVHHDVF FSERTLHADN ARKIRSAIND LTLKGHIYKG KLPPPKGEKP
310 320 330 340 350
DDWEDREQTL FRSTAVGDDM DRALVKSDGS FTYFAADVAY LKDKVDRGFV
360 370 380 390 400
DLIYVLGADH GGYVKRLEAL ARAIAGDEVK LTVLLCNLVK LYRDGEPIRM
410 420 430 440 450
SKRSGDFVTL REVVEEVGRD AIRFMMLYRK SDAPLDFDFA KVTEQSKDNP
460 470 480 490 500
VFYVQYASAR CHSVFRQASE QLGEANFDRK SLAAAAASLT DEGEIGLIRK
510 520 530 540 550
LAEYPRLIES AALALEPHRL AFYLYDLASS FHGHWNRGTD NPDLRFVKVN
560 570 580
DRQLTHARLG LVQAVSDVLT SGLTLIGAAA PTEMR
Length:585
Mass (Da):64,095
Last modified:October 1, 2001 - v1
Checksum:i18B77DA8DDEC2C0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000012 Genomic DNA Translation: BAB48543.1
RefSeqiWP_010909897.1, NC_002678.2

Genome annotation databases

EnsemblBacteriaiBAB48543; BAB48543; BAB48543
KEGGimlo:mll1091
PATRICifig|266835.9.peg.881

Similar proteinsi

Entry informationi

Entry nameiSYR_RHILO
AccessioniPrimary (citable) accession number: Q98LC0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: October 1, 2001
Last modified: May 23, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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