Reviewed, UniProtKB/Swiss-Prot Q98G36 (ARLY1_RHILO)

Names and origin

Protein names

Recommended name:
    Argininosuccinate lyase 1
      Short name=ASAL 1
    EC=4.3.2.1
Alternative name(s):
    Arginosuccinase 1

Gene names

Name:	argH1
Ordered Locus Names:	mlr3506

Organism

Rhizobium loti (Mesorhizobium loti) [Complete proteome] [HAMAP]

Taxonomic identifier

381 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Mesorhizobium

Protein attributes

Sequence length	466 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. HAMAP MF_00006
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. HAMAP MF_00006
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis
Cellular component	Cytoplasm
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process via ornithine Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	argininosuccinate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 466	466	Argininosuccinate lyase 1 HAMAP MF_00006		PRO_0000137810

Sequences

	Sequence		Length	Mass (Da)
	Q98G36-1 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 7786404E0CFDC557	FASTA	466	50,778
	10 20 30 40 50 60 MSDKKTSNQM WGGRFASGPA AIMEAINASI SFDRKLYAQD IRGSIAHSEM LAQTGIISTA 70 80 90 100 110 120 DQEKIAHGLN TILKEIEAGS FEFSTRLEDI HMNVEARLAD LIGSAAGRLH TARSRNDQVA 130 140 150 160 170 180 VDLRLWVKDE CFRVAEALKG LITALLARAE EHAATVMPGF THMQAAQPVT FGHHCMAYVE 190 200 210 220 230 240 MFARDLSRVR DAIERMDESP LGAAALAGTS FPIDRHRTAK ALGFREPMRN SLDSVSDRDF 250 260 270 280 290 300 ALDFLAMAAI CATHLSRLAE EIIIWSTPQF GFIRLSDSFS TGSSIMPQKK NPDAAELVRG 310 320 330 340 350 360 KTGRVNGHLV GLLTVMKGMP LTYGKDMQED KESVFDAAET LDLMLAAMTG MVSDMTVNAA 370 380 390 400 410 420 AMKKAAGSGH ATATDLADWL VRTLGLPFRE AHHVTGRAVA LAEEKKVSLE KLSLEDLQSI 430 440 450 460 NPGITADIFS VLAVQNSVKS RTSFGGTAPS EVRKQIRYWK KRLAKA

References

[1]

"Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti." Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S., Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y., Nakayama S. , Nakazaki N., Shimpo S., Sugimoto M., Takeuchi C., Yamada M., Tabata S. DNA Res. 7:331-338(2000) [PubMed: 11214968] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MAFF303099.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000012 Genomic DNA. Translation: BAB50380.1.
RefSeq	NP_104594.1.
3D structure databases
HSSP	HSSP built from PDB template 1DCN based on UniProtKB P24058.
ModBase	Search...
Genome annotation databases
GeneID	1227255.
GenomeReviews	Gene locus mlr3506 in contig BA000012_GR.
KEGG	mlo:mlr3506.
NMPDR	fig|266835.1.peg.2698.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q98G36.
OMA	MAEDLIF.
Enzyme and pathway databases
BRENDA	4.3.2.1. 3315.
Family and domain databases
HAMAP	MF_00006. [Tree]
InterPro	IPR009049. Argininosuccinate_lyase. IPR003031. D_crystallin. IPR000362. Fumarate_lyase. IPR020557. Fumarate_lyase_CS. [Graphical view]
PANTHER	PTHR11444:SF3. argH. 1 hit.
Pfam	PF00206. Lyase_1. 1 hit. [Graphical view]
PRINTS	PR00145. ARGSUCLYASE. PR00149. FUMRATELYASE.
TIGRFAMs	TIGR00838. argH. 1 hit.
PROSITE	PS00163. FUMARATE_LYASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ARLY1_RHILO

Accession

Primary (citable) accession number: Q98G36

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 27, 2002
Last sequence update:	October 1, 2001
Last modified:	November 3, 2009
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)