Reviewed,
UniProtKB/Swiss-Prot Q98G10 (HIS82_RHILO)
Last modified
February 9, 2010.
Version 50.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Histidinol-phosphate aminotransferase 2 EC=2.6.1.9 Alternative name(s): Imidazole acetol-phosphate transaminase 2 | ||||
| Gene names |
| ||||
| Organism | Rhizobium loti (Mesorhizobium loti) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 381 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Mesorhizobium |
Protein attributes
| Sequence length | 369 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 |
| Cofactor | Pyridoxal phosphate By similarity. HAMAP MF_01023 |
| Pathway | Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 |
| Subunit structure | Homodimer By similarity. HAMAP MF_01023 |
| Sequence similarities | Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Histidine biosynthesis |
| Ligand | Pyridoxal phosphate |
| Molecular function | Aminotransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Molecular function | histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 369 | 369 | Histidinol-phosphate aminotransferase 2 HAMAP MF_01023 | PRO_0000153433 | |||||
Amino acid modifications | |||||||||
| Modified residue | 227 | 1 | N6-(pyridoxal phosphate)lysine By similarity | ||||||
Sequences
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References
| [1] | "Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti." Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S., Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y., Nakayama S. Tabata S.DNA Res. 7:331-338(2000) [PubMed: 11214968] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MAFF303099. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BA000012 Genomic DNA. Translation: BAB50406.1. |
| RefSeq | NP_104620.1. |
3D structure databases | |
| SMR | Q98G10. Positions 12-364. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1227281. |
| GenomeReviews | Gene locus mll3536 in contig BA000012_GR. |
| KEGG | mlo:mll3536. |
| NMPDR | fig|266835.1.peg.2724. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG646350. |
| OMA | PRTKIVF. |
Enzyme and pathway databases | |
| BRENDA | 2.6.1.9. 3315. |
Family and domain databases | |
| HAMAP | MF_01023. HisC_aminotrans_2. [Tree] |
| InterPro | IPR004839. Aminotransferase_I/II. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view] |
| Gene3D | G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. |
| Pfam | PF00155. Aminotran_1_2. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01141. hisC. 1 hit. |
| PROSITE | PS00599. AA_TRANSFER_CLASS_2. False negative. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | HIS82_RHILO | ||||||||
| Accession | Primary (citable) accession number: Q98G10 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


