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Q98FJ1 (PGK_RHILO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:mlr3753
OrganismRhizobium loti (strain MAFF303099) (Mesorhizobium loti) [Complete proteome] [HAMAP]
Taxonomic identifier266835 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 398398Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145992

Regions

Nucleotide binding355 – 3584ATP By similarity
Region23 – 253Substrate binding By similarity
Region61 – 644Substrate binding By similarity

Sites

Binding site381Substrate By similarity
Binding site1201Substrate By similarity
Binding site1531Substrate By similarity
Binding site2031ATP By similarity
Binding site3251ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q98FJ1 [UniParc].

Last modified October 1, 2001. Version 1.
Checksum: 965669CB04C0A5FD

FASTA39841,304
        10         20         30         40         50         60 
MAAFKTLDDI GNISGKRVLV RVDLNVPVAD GKVTDATRIE RIAPTIAELS GKGAKVILLA 

        70         80         90        100        110        120 
HFGRPKDGPS PEFSLEPIAR ATAEVLGRPV GFASDCVGDM AGSAVAAMNK GDVLLFENTR 

       130        140        150        160        170        180 
FYKAEEKNDP AFSERLAANG DIFVNDAFSA AHRAHSSTEG LARLLPSFAG RTMQAELEAL 

       190        200        210        220        230        240 
EKGLGNPVRP VVAIVGGAKV STKIDLLMNL VKKVDALVIG GGMANTFLAA RGTDVGKSLC 

       250        260        270        280        290        300 
EHDLAPTAKQ IMIEAAEAGC AIILPVDGVV AKEFKAGAAC ETVAISDVPA DGMILDVGEK 

       310        320        330        340        350        360 
TVKTIGEWID RAATLVWNGP LGAFEIEPFD HATVAAAKHA AARTKAGKLV SVAGGGDTVA 

       370        380        390 
ALNHAGVADD FTYVSTAGGA FLEWMEGKPL PGVDVLKR 

« Hide

References

[1]"Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti."
Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S., Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y., Nakayama S. expand/collapse author list , Nakazaki N., Shimpo S., Sugimoto M., Takeuchi C., Yamada M., Tabata S.
DNA Res. 7:331-338(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MAFF303099.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000012 Genomic DNA. Translation: BAB50576.1.
RefSeqNP_104790.1. NC_002678.2.

3D structure databases

ProteinModelPortalQ98FJ1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING266835.mlr3753.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB50576; BAB50576; BAB50576.
GeneID1227451.
KEGGmlo:mlr3753.
PATRIC22480197. VBIMesLot2464_2987.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAREKNCAI.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycMLOT266835:GJ9L-2932-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_RHILO
AccessionPrimary (citable) accession number: Q98FJ1
Entry history
Integrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: October 1, 2001
Last modified: June 11, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways