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Protein

Uronate isomerase

Gene

uxaC

Organism
Rhizobium loti (strain MAFF303099) (Mesorhizobium loti)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciMLOT266835:GJ9L-3163-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:mll4056
OrganismiRhizobium loti (strain MAFF303099) (Mesorhizobium loti)
Taxonomic identifieri266835 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
Proteomesi
  • UP000000552 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 469469Uronate isomerasePRO_0000172781Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266835.mll4056.

Structurei

3D structure databases

ProteinModelPortaliQ98EW1.
SMRiQ98EW1. Positions 8-469.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000238114.
KOiK01812.
OMAiGHTDPRW.
OrthoDBiEOG6J1D95.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

Q98EW1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVALTDPDLL FPPEAHSRSL ARDLYAGIKD LPIVSPHGHT DPRWYALNEP
60 70 80 90 100
FPDPAQLLIV PDHYIFRMLF SQGVRLEDLG VASLDGAPVE TDGRTIWRRF
110 120 130 140 150
AEHYYLFRGT PTRLWFDHVL AHLFGIEEPL DATTADRHYD TIATVLQWEN
160 170 180 190 200
FRPRALFERF NIEVIATTEG ALDDLEWHKM IRDSGWEGRV VTAYRPDAVV
210 220 230 240 250
DPDFEGFSAN LDRLGEITGC DTGSWAGYLD AHRQRRAFFK SFGATSSDHG
260 270 280 290 300
HPTAETANLS DAAAQELFNR IRRGSQDERE RKLFRAQMLT EMAKMSRDDG
310 320 330 340 350
LVLQIHPGSW RNHSPSVFQR FGRDKGFDIP TRTDYVTALK PLLDCVGLER
360 370 380 390 400
DLTVILFTLD ESSYARELAP LAGVYPALKL GPAWWFHDSP EGMRRFREMT
410 420 430 440 450
TETAGFYNTV GFNDDTRAFP SIPARHDVAR RVDCAFLARL VAEHRLREDE
460
AHELARELAH TLAKKAYRL
Length:469
Mass (Da):53,525
Last modified:October 1, 2001 - v1
Checksum:i5EF8527AA61DC16D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000012 Genomic DNA. Translation: BAB50806.1.
RefSeqiWP_010912149.1. NC_002678.2.

Genome annotation databases

EnsemblBacteriaiBAB50806; BAB50806; BAB50806.
GeneIDi1227681.
KEGGimlo:mll4056.
PATRICi22480649. VBIMesLot2464_3212.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000012 Genomic DNA. Translation: BAB50806.1.
RefSeqiWP_010912149.1. NC_002678.2.

3D structure databases

ProteinModelPortaliQ98EW1.
SMRiQ98EW1. Positions 8-469.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi266835.mll4056.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB50806; BAB50806; BAB50806.
GeneIDi1227681.
KEGGimlo:mll4056.
PATRICi22480649. VBIMesLot2464_3212.

Phylogenomic databases

eggNOGiENOG4105D2H. Bacteria.
COG1904. LUCA.
HOGENOMiHOG000238114.
KOiK01812.
OMAiGHTDPRW.
OrthoDBiEOG6J1D95.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciMLOT266835:GJ9L-3163-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MAFF303099.

Entry informationi

Entry nameiUXAC_RHILO
AccessioniPrimary (citable) accession number: Q98EW1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: October 1, 2001
Last modified: November 11, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.