ID   Q98DR2_RHILO            Unreviewed;       458 AA.
AC   Q98DR2;
DT   01-OCT-2001, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2001, sequence version 1.
DT   27-MAR-2024, entry version 98.
DE   SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:BAB51208.1};
GN   OrderedLocusNames=mlr4588 {ECO:0000313|EMBL:BAB51208.1};
OS   Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)
OS   (Mesorhizobium loti (strain MAFF 303099)).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=266835 {ECO:0000313|EMBL:BAB51208.1, ECO:0000313|Proteomes:UP000000552};
RN   [1] {ECO:0000313|EMBL:BAB51208.1, ECO:0000313|Proteomes:UP000000552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 29417 / CECT 9101 / MAFF 303099
RC   {ECO:0000313|Proteomes:UP000000552};
RX   PubMed=11214968; DOI=10.1093/dnares/7.6.331;
RA   Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y.,
RA   Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y.,
RA   Nakayama S., Nakazaki N., Shimpo S., Sugimoto M., Takeuchi C., Yamada M.,
RA   Tabata S.;
RT   "Complete genome structure of the nitrogen-fixing symbiotic bacterium
RT   Mesorhizobium loti.";
RL   DNA Res. 7:331-338(2000).
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DR   EMBL; BA000012; BAB51208.1; -; Genomic_DNA.
DR   RefSeq; WP_010912550.1; NC_002678.2.
DR   AlphaFoldDB; Q98DR2; -.
DR   KEGG; mlo:mlr4588; -.
DR   PATRIC; fig|266835.9.peg.3623; -.
DR   eggNOG; COG2114; Bacteria.
DR   HOGENOM; CLU_033715_2_0_5; -.
DR   Proteomes; UP000000552; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        55..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        123..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        150..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          262..394
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   458 AA;  50520 MW;  6E1EFA463C80867D CRC64;
     MPTAPTLELR RYSRLKNLRA RAERQGAALQ FWARTASLAA ISCFFSLISR WDASLLFVLA
     GLVLFQLVGL IQFLFARRRT APWWIGYLVG TLDIILLTIL LVTPNPFSQE VAPAAMQLRE
     GSFKFLLIFI CLGALTLSTR LALYLGALAA LTWAIGVGWV ISHPGTVIPA TNLYSLPVTE
     RLNLYLNPNF VDTFAQATNV LVVLIIGAIM ALVVSRSRRL SEDYVKAERA RANLARHFSP
     NVVDQLATDD EPFGPVRRQD IAVLFADIVG FTHYSEDHPA EAVFELLRQF HRRMEQVVFD
     HHGTVDNYIG DCIMATFGVP QASHDDATRA IQCAEAMVAA LEDWNVQRVS RGYPPLDVRI
     GAQYGAVVIG AVGSERNLSF AVVGDTVNVA SRLQSLCREL QANICFGSRL IEAAKAESPT
     TRLNARDHGP VSIRGRDEPV HVWVERRAES QGAVAVSA
//