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Q98DK4 (MASZ_RHILO) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Malate synthase G
EC=2.3.3.9
Gene names
Name:glcB
Ordered Locus Names:mlr4664
OrganismRhizobium loti (strain MAFF303099) (Mesorhizobium loti) [Complete proteome] [HAMAP]
Taxonomic identifier266835 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Mesorhizobium

Protein attributes

Sequence length721 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. HAMAP MF_00641

Pathway

Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. HAMAP MF_00641

Subunit structure

Monomer By similarity. HAMAP MF_00641

Subcellular location

Cytoplasm By similarity HAMAP MF_00641.

Sequence similarities

Belongs to the malate synthase family. GlcB subfamily.

Ontologies

Keywords
   Biological processGlyoxylate bypass
Tricarboxylic acid cycle
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglyoxylate cycle

Inferred from electronic annotation. Source: UniProtKB-KW

tricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmalate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 721721Malate synthase G HAMAP MF_00641
PRO_0000166896

Sites

Active site3381Proton acceptor By similarity
Active site6291Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q98DK4 [UniParc].

Last modified October 1, 2001. Version 1.
Checksum: 65376311A7E1BFDF

FASTA72178,059
        10         20         30         40         50         60 
MTDRIEIAGL RIAGELHDFV AGEALPGTGI AADAFWSGFS AIVHDLAPKN RALLKKRDAM 

        70         80         90        100        110        120 
QERLDGWYRD NGAPVDMEVY KSFLKEIGYL VPEGPAFSVS TDNVDPEIAV VAGPQLVVPV 

       130        140        150        160        170        180 
MNARYALNAA NARWGSLYDA LYGTDAIPET GGAEKGKGFN PARGAKVIAW AKDFLDQSVP 

       190        200        210        220        230        240 
LTSGKWAGVN GLSVAHGALK LGAGAGGTTL ADPRQFAGYR GDAANPDAVL LVKNGLHIEI 

       250        260        270        280        290        300 
VVDRNNQIGR TDPAGIADVI LESALTTIQD CEDSVAAVDA QDKVVVYRNW LGLMKGDLAE 

       310        320        330        340        350        360 
EISKAGRSFV RKLNADRAYT APAGGQITVP GRSLMLVRNV GHLMTNPAIL DRDGNEVPEG 

       370        380        390        400        410        420 
IMDAALTALI ALHDVGPEGR RANSRAGSMY VVKPKMHGPE EVAFAVEIFD RVEALLGMPR 

       430        440        450        460        470        480 
NTIKMGIMDE ERRTTVNLKE AIRAARERVV FINTGFLDRT GDEIHTSMEA GPMIRKGDMK 

       490        500        510        520        530        540 
QAAWISAYEA WNVDTGLECG LAGHAQIGKG MWAMPDLMAA MLEQKIAHPK AGANTAWVPS 

       550        560        570        580        590        600 
PTAATLHATH YHKVDVHAVQ AALKSRPKAK LDDILSVPVA VRPNWTPDEI QRELDNNAQG 

       610        620        630        640        650        660 
ILGYVVRWID QGVGCSKVPD INDVGLMEDR ATLRISSQHI ANWLRHKVCS EIQVRDSLQR 

       670        680        690        700        710        720 
MAAIVDRQNV GDPLYRPMAP DFDKSIAFQA ACDLVFKGTS QPNGYTEPVL HARRLELKAQ 


R

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000012 Genomic DNA. Translation: BAB51267.1.
RefSeqNP_105481.1. NC_002678.2.

3D structure databases

ProteinModelPortalQ98DK4.
SMRQ98DK4. Positions 2-720.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1228142.
GenomeReviewsGene locus mlr4664 in contig BA000012_GR.
KEGGmlo:mlr4664.
NMPDRfig|266835.1.peg.3585.
PATRIC22481607. VBIMesLot2464_3688.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG350005.
OMAPKMHGPD.
ProtClustDBPRK02999.

Family and domain databases

HAMAPMF_00641. Malate_synth_G.
[Tree]
InterProIPR011076. Malate_synth-like.
IPR023310. Malate_synth_G_beta_sub_dom.
IPR001465. Malate_synthase.
IPR006253. Malate_synthG.
[Graphical view]
Gene3DG3DSA:2.170.170.11. Malate_synth_G_beta_sub_dom. 2 hits.
KOK01638.
PANTHERPTHR21631:SF1. Malate_synthase. 1 hit.
PfamPF01274. Malate_synthase. 1 hit.
[Graphical view]
SUPFAMSSF51645. Malat_synth_like. 1 hit.
TIGRFAMsTIGR01345. Malate_syn_G. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMASZ_RHILO
AccessionPrimary (citable) accession number: Q98DK4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 30, 2003
Last sequence update: October 1, 2001
Last modified: January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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