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Q98D24

- PNCB_RHILO

UniProt

Q98D24 - PNCB_RHILO

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Protein
Nicotinate phosphoribosyltransferase
Gene
pncB, mll4892
Organism
Rhizobium loti (strain MAFF303099) (Mesorhizobium loti)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate phosphoribosyltransferase activity Source: InterPro
  3. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciMLOT266835:GJ9L-3808-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferase (EC:6.3.4.21)
Short name:
NAPRTase
Gene namesi
Name:pncB
Ordered Locus Names:mll4892
OrganismiRhizobium loti (strain MAFF303099) (Mesorhizobium loti)
Taxonomic identifieri266835 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium
ProteomesiUP000000552: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 434434Nicotinate phosphoribosyltransferaseUniRule annotation
PRO_0000205841Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi266835.mll4892.

Structurei

3D structure databases

ProteinModelPortaliQ98D24.
SMRiQ98D24. Positions 1-426.

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284929.
KOiK00763.
OMAiSIVCKVI.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q98D24-1 [UniParc]FASTAAdd to Basket

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MARTDIARRV YNHTWKLDPI VRSLLDTDFY KLLMLQMIWG MYPKVDATFS    50
LINRTTSVRL ADEIDEGELR EQLDHARTLR FSKKEMIWLG GNNFYGRKQI 100
FEPEFLAWLE GFRLPDYELS KRDGQYELSF SGPWMYTTLW EIPALAIINE 150
LRSRAAMRAF GPFALDVLYA RAKAKMWAKT ERLKALPGIR ISDFGTRRRH 200
SFLWQRWCVE ALKEGIGEAF TGTSNVLLAM DNDLEALGTN AHELPMVFAA 250
LANSEKELKQ APYKVLQDWQ RYYGGNLLIV LPDAFGTASF LRDAPDWVAD 300
WTGFRPDSAP PIEGGEKILS WWRERGKDPK QKLLIFSDGL EVETIEETYR 350
HFKGKVRMSF GWGTNLTNDF EGCAPTETNS LDAISLVCKV TEANGRPAVK 400
LSDNPAKATG DEKEIERYLR IFGEKDRVEQ LVKV 434
Length:434
Mass (Da):49,889
Last modified:October 1, 2001 - v1
Checksum:iEBA1579A9094430F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000012 Genomic DNA. Translation: BAB51447.1.
RefSeqiNP_105661.1. NC_002678.2.

Genome annotation databases

EnsemblBacteriaiBAB51447; BAB51447; BAB51447.
GeneIDi1228322.
KEGGimlo:mll4892.
PATRICi22481966. VBIMesLot2464_3866.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000012 Genomic DNA. Translation: BAB51447.1 .
RefSeqi NP_105661.1. NC_002678.2.

3D structure databases

ProteinModelPortali Q98D24.
SMRi Q98D24. Positions 1-426.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 266835.mll4892.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB51447 ; BAB51447 ; BAB51447 .
GeneIDi 1228322.
KEGGi mlo:mll4892.
PATRICi 22481966. VBIMesLot2464_3866.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284929.
KOi K00763.
OMAi SIVCKVI.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci MLOT266835:GJ9L-3808-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MAFF303099.

Entry informationi

Entry nameiPNCB_RHILO
AccessioniPrimary (citable) accession number: Q98D24
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: October 1, 2001
Last modified: September 3, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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