Q98D10 (XYLD_RHILO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative D-xylulose reductase
EC=1.1.1.9

Alternative name(s):
Xylitol dehydrogenase
Short name=XDH

Gene names

Ordered Locus Names:

mlr4915

Organism

Rhizobium loti (strain MAFF303099) (Mesorhizobium loti) [Complete proteome] [HAMAP]

Taxonomic identifier

266835 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Mesorhizobium

Protein attributes

Sequence length	348 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Xylitol + NAD+ = D-xylulose + NADH.
Cofactor	Binds 1 zinc ion per subunit By similarity.
Sequence similarities	Belongs to the zinc-containing alcohol dehydrogenase family.

Ontologies

Keywords
Ligand	Metal-binding NAD Zinc
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	D-xylulose reductase activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 348	348	Putative D-xylulose reductase		PRO_0000160886
Sites
	Metal binding	38	1	Zinc; catalytic By similarity
	Metal binding	63	1	Zinc; catalytic By similarity
	Metal binding	149	1	Zinc; catalytic By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q98D10 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 5323000209211076	FASTA	348	36,355
	10 20 30 40 50 60 MRALVLEKKG ELSLREIALP LDVGPDDVKI AIHTVGVCGS DVHYYTHGAI GSYVVRAPMV 70 80 90 100 110 120 LGHEAAGTVV ETGANVETFK AGDRVCMEPG VPNLSSRATK LGIYNVDPDV SFWATPPVHG 130 140 150 160 170 180 VLAPYAVHPA AFTYKLPDNV SFAEGAMVEP FAIGMQAASR ARIVPGDVAV VVGCGPIGIM 190 200 210 220 230 240 IALAALAGGC SKVLISDFSA PKLKIAAQYA GIVPVNIGER SLVDAVAAAT DKWGADIVFE 250 260 270 280 290 300 ASGSPKAFAD LFDVVRPGGA VVLVGLPVEP VALNVPAAIS KEVRIETVFR YANIFDRALQ 310 320 330 340 LIASGKVDLK PLITGTYDFA DSIKAFERAA QGNPEDVKLQ ILLTGEKG

References

[1]

"Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti." Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S., Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y., Nakayama S. , Nakazaki N., Shimpo S., Sugimoto M., Takeuchi C., Yamada M., Tabata S. DNA Res. 7:331-338(2000) [PubMed: 11214968] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MAFF303099.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000012 Genomic DNA. Translation: BAB51461.1.
RefSeq	NP_105675.1. NC_002678.2.
3D structure databases
ProteinModelPortal	Q98D10.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1228336.
GenomeReviews	Gene locus mlr4915 in contig BA000012_GR.
KEGG	mlo:mlr4915.
NMPDR	fig|266835.1.peg.3779.
PATRIC	22481996. VBIMesLot2464_3881.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG753318.
OMA	RDIDIPQ.
ProtClustDB	CLSK864144.
Family and domain databases
InterPro	IPR013149. ADH_C. IPR013154. ADH_GroES-like. IPR002085. ADH_SF_Zn-type. IPR002328. ADH_Zn_CS. IPR011032. GroES-like. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K05351.
PANTHER	PTHR11695. ADH_Sf_Zn. 1 hit.
Pfam	PF08240. ADH_N. 1 hit. PF00107. ADH_zinc_N. 1 hit. [Graphical view]
SUPFAM	SSF50129. GroES_like. 1 hit.
PROSITE	PS00059. ADH_ZINC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYLD_RHILO

Accession

Primary (citable) accession number: Q98D10

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 19, 2003
Last sequence update:	October 1, 2001
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program