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Q98BV5 (G6PI_RHILO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:mlr5411
OrganismRhizobium loti (strain MAFF303099) (Mesorhizobium loti) [Complete proteome] [HAMAP]
Taxonomic identifier266835 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesPhyllobacteriaceaeMesorhizobium

Protein attributes

Sequence length547 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 547547Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180718

Sites

Active site3501Proton donor By similarity
Active site3811 By similarity
Active site5101 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q98BV5 [UniParc].

Last modified October 1, 2001. Version 1.
Checksum: 2275A5B6135BF86F

FASTA54759,096
        10         20         30         40         50         60 
MDKSAFQKQL AALRDHRSAA PASMRQAFAA DPQRFQAFTA TDGDLLLDWS KCAVDATTMD 

        70         80         90        100        110        120 
LLEKLAAAAD LEGRRAAMFA GKKINITEDR AVLHTALRNL SGTGVTVDGQ DVKADVLSVL 

       130        140        150        160        170        180 
DAMGAFADAI RSGKALGATG KKITDIVNIG IGGSDLGPAM ATLALAPYHD GPRAHYVSNI 

       190        200        210        220        230        240 
DGAHIHDTLK GLSAETTLFI VASKTFTTVE TMTNAQTARD WVQKALGKQA VGKHFAAVST 

       250        260        270        280        290        300 
ALDLVAKFGI EADRVFGFWD WVGGRYSVWG AIGLPVMIAV GPRNFRAFLD GAHEMDQHFR 

       310        320        330        340        350        360 
TAPLAGNLPA LLGLVGWWHR VICGYPARAV IPYDQRLSRL PAYLQQLDME SNGKGVTLDG 

       370        380        390        400        410        420 
TPVATPTGPL VWGEPGTNGQ HAFFQLLHQG TDFIPVEFLA AAVGHEPELK HQHDLLLANC 

       430        440        450        460        470        480 
LAQSEALMKG RTLDEARAQM LAKGMKPADV DKIAPHRVFS GNRPSLTILY RKLDPRTFGR 

       490        500        510        520        530        540 
LIALYEHRVF VEGTLFNINS FDQWGVELGK ELATGLLPVV EGKESAANRD ASTRGLVERI 


HQLRGSE 

« Hide

References

[1]"Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti."
Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S., Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y., Nakayama S. expand/collapse author list , Nakazaki N., Shimpo S., Sugimoto M., Takeuchi C., Yamada M., Tabata S.
DNA Res. 7:331-338(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MAFF303099.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000012 Genomic DNA. Translation: BAB51867.1.
RefSeqNP_106081.1. NC_002678.2.

3D structure databases

ProteinModelPortalQ98BV5.
SMRQ98BV5. Positions 12-546.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING266835.mlr5411.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB51867; BAB51867; BAB51867.
GeneID1228742.
KEGGmlo:mlr5411.
PATRIC22482828. VBIMesLot2464_4295.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMARAHYVSN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycMLOT266835:GJ9L-4230-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_RHILO
AccessionPrimary (citable) accession number: Q98BV5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: October 1, 2001
Last modified: June 11, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways