Reviewed, UniProtKB/Swiss-Prot Q98B00 (HIS83_RHILO)

Names and origin

Protein names

Recommended name:
    Histidinol-phosphate aminotransferase 3
    EC=2.6.1.9
Alternative name(s):
    Imidazole acetol-phosphate transaminase 3

Gene names

Name:	hisC3
Ordered Locus Names:	mlr5786

Organism

Rhizobium loti (Mesorhizobium loti) [Complete proteome] [HAMAP]

Taxonomic identifier

381 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Mesorhizobium

Protein attributes

Sequence length	369 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023
Cofactor	Pyridoxal phosphate By similarity.
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis
Ligand	Pyridoxal phosphate
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 369	369	Histidinol-phosphate aminotransferase 3 HAMAP MF_01023		PRO_0000153434
Amino acid modifications
	Modified residue	220	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q98B00-1 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: DCB23E0507165570	FASTA	369	40,711
	10 20 30 40 50 60 MSDAKLQSVL SSLSQVARQL DALPSDTPAP DSSWVKLNTN ENPFPLPEII MQSAIAALER 70 80 90 100 110 120 QYLYPEDDNI SLREAAANAY SVSMDQVIAG NGSSELLGLV YRAFLTPGDS VAMMSPGFSF 130 140 150 160 170 180 NRKLATLQGA QFVEIEFSKD HSLPMEQLLF GPAKDAKFIL LANPNNPTGT FVPVADIERL 190 200 210 220 230 240 VAKSDRLIVL DEAYVDFAPE NGLRLINRYS NLLVLRTFSK SYAAAGVRVG FGFGHPEIIG 250 260 270 280 290 300 RLRNIQNVFN MNVIGQAVGI SVLAHRAAYA DNHRHIRHER RRVTLALSQL GFSVIPSHAN 310 320 330 340 350 360 FLLARVPTAQ DGSWWQSAFA RQKILVAVFP DKGLENYIRV SIGTKEQMDA FLRAASRISR ILNMSTPPR

References

[1]

"Complete genome structure of the nitrogen-fixing symbiotic bacterium Mesorhizobium loti." Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S., Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y., Nakayama S. , Nakazaki N., Shimpo S., Sugimoto M., Takeuchi C., Yamada M., Tabata S. DNA Res. 7:331-338(2000) [PubMed: 11214968] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MAFF303099.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000012 Genomic DNA. Translation: BAB52172.1.
RefSeq	NP_106386.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1229045.
GenomeReviews	Gene locus mlr5786 in contig BA000012_GR.
KEGG	mlo:mlr5786.
NMPDR	fig|266835.1.peg.4489.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q98B00.
OMA	HIRHERR.
Enzyme and pathway databases
BRENDA	2.6.1.9. 3315.
Family and domain databases
HAMAP	MF_01023. [Tree]
InterPro	IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR005861. HisP_aminotrans. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
TIGRFAMs	TIGR01141. hisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HIS83_RHILO

Accession

Primary (citable) accession number: Q98B00

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 11, 2002
Last sequence update:	October 1, 2001
Last modified:	November 3, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)