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Q989E5 (MURA1_RHILO) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1
EC=2.5.1.7
Alternative name(s):
Enoylpyruvate transferase 1
UDP-N-acetylglucosamine enolpyruvyl transferase 1
Short name=EPT 1
Gene names
Name:murA1
Ordered Locus Names:mll6459
OrganismRhizobium loti (strain MAFF303099) (Mesorhizobium loti) [Complete proteome] [HAMAP]
Taxonomic identifier266835 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Mesorhizobium

Protein attributes

Sequence length430 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine By similarity. HAMAP MF_00111

Catalytic activity

Phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine. HAMAP MF_00111

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00111

Subcellular location

Cytoplasm Probable HAMAP MF_00111.

Sequence similarities

Belongs to the EPSP synthase family. MurA subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 430430UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 HAMAP MF_00111
PRO_0000178906

Sites

Active site1261Proton donor By similarity

Amino acid modifications

Modified residue12612-(S-cysteinyl)pyruvic acid O-phosphothioketal By similarity

Sequences

Sequence LengthMass (Da)Tools
Q989E5 [UniParc].

Last modified October 1, 2001. Version 1.
Checksum: 2D35ABD2D463CBBC

FASTA43045,535
        10         20         30         40         50         60 
MDRIRIVGGN KLAGSIPISG AKNAALPLMI ASLLTDDTLT LENVPHLADV EQLIRILGNH 

        70         80         90        100        110        120 
GVDYSVNGRR EKQNEGYSRT INFSARNIVD TTAPYELVSK MRASFWVIGP LLARMGEAKV 

       130        140        150        160        170        180 
SLPGGCAIGT RPVDLFLEGL QALGADLDVD TGYVIAKTKN GRLVGNRYVF PKVSVGATHV 

       190        200        210        220        230        240 
LMMAASLAKG ETVLENAACE PEIVNLAECL NAMGARISGA GTPTITIDGV ESLSGARVRV 

       250        260        270        280        290        300 
IPDRIETGTY AMAVAMTGGD VVLEGARPEL LQTALDVISQ TGAEITQTNS GIRVKRNGAG 

       310        320        330        340        350        360 
ISPVDVTTAP FPAFPTDLQA QFMGLMTMAK GKSRITETIF ENRFMHVQEL ARLGAHITLS 

       370        380        390        400        410        420 
GQTAIVDGVA KLKGAPVMAT DLRASVSLVI AGLAAEGETT VNRVYHLDRG FERLEEKLSN 

       430 
CGAVIERISA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000012 Genomic DNA. Translation: BAB52752.1.
RefSeqNP_106966.1. NC_002678.2.

3D structure databases

ProteinModelPortalQ989E5.
SMRQ989E5. Positions 1-429.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1229621.
GenomeReviewsGene locus mll6459 in contig BA000012_GR.
KEGGmlo:mll6459.
NMPDRfig|266835.1.peg.5067.
PATRIC22484495. VBIMesLot2464_5129.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG482701.
OMAGYEHIED.
ProtClustDBPRK09369.

Family and domain databases

HAMAPMF_00111. MurA.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
IPR005750. UDP_GlcNAc_COvinyl_MurA.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00790.
PANTHERPTHR21090:SF4. AcGlu_Tran_MurA. 1 hit.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01072. MurA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMURA1_RHILO
AccessionPrimary (citable) accession number: Q989E5
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2002
Last sequence update: October 1, 2001
Last modified: January 25, 2012
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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