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Protein
Submitted name:

Mx1 protein

Gene

mx1

Organism
Salmo salar (Atlantic salmon)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular response to interferon-alpha Source: AgBase
  • response to type I interferon Source: AgBase
Complete GO annotation...

Keywords - Ligandi

GTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Mx1 proteinImported
Submitted name:
Myxovirus resistance 1Imported
Gene namesi
Name:mx1Imported
OrganismiSalmo salar (Atlantic salmon)Imported
Taxonomic identifieri8030 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiProtacanthopterygiiSalmoniformesSalmonidaeSalmoninaeSalmo

Subcellular locationi

GO - Cellular componenti

  • cell Source: AgBase
Complete GO annotation...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini31 – 304274Dynamin-type G (guanine nucleotide-binding)InterPro annotationAdd
BLAST
Domaini537 – 62387GEDInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.UniRule annotationSAAS annotation
Contains GED domain.SAAS annotation
Contains dynamin-type G (guanine nucleotide-binding) domain.SAAS annotation

Phylogenomic databases

HOVERGENiHBG008788.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR000375. Dynamin_central.
IPR001401. Dynamin_GTPase.
IPR019762. Dynamin_GTPase_CS.
IPR022812. Dynamin_SF.
IPR030381. G_DYNAMIN_dom.
IPR003130. GED.
IPR020850. GED_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11566. PTHR11566. 1 hit.
PfamiPF01031. Dynamin_M. 1 hit.
PF00350. Dynamin_N. 1 hit.
PF02212. GED. 1 hit.
[Graphical view]
PRINTSiPR00195. DYNAMIN.
SMARTiSM00053. DYNc. 1 hit.
SM00302. GED. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00410. G_DYNAMIN_1. 1 hit.
PS51718. G_DYNAMIN_2. 1 hit.
PS51388. GED. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q98990-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNTLNQHYE EKVRPCIDLI DSLRSLGVEK DLALPAIAVI GDQSSGKSSV
60 70 80 90 100
LEALSGVALP RGSGIVTRCP LELKMKRKKE GEEWHGKISY QDHEEEIEDP
110 120 130 140 150
SDVEKKIREA QDEMAGVGVG ISDDLISLEI GSPDVPDLTL IDLPGIARVA
160 170 180 190 200
VKGQPENIGE QIKRLIRKFI TKQETINLVV VPCNVDIATT EALKMAQEVD
210 220 230 240 250
PEGERTLGIL TKPDLVDKGT EETVVDIVHN EVIHLTKGYM IVKCRGQKEI
260 270 280 290 300
MERVSLSEAT EREKAFFKEH AHLSTLYDEG HATIPKLAEK LTLELVHHIE
310 320 330 340 350
KSLPRLEEQI EAKLAETHAE LERYGTGPPE DSAERMYFLI DKVTAFTHDA
360 370 380 390 400
INLSTGEELK SGVRLNVFST LRKEFGKWKL HLDHSGENFN QRIEGEVADY
410 420 430 440 450
EKTYRGRELP GFINYKTFEV MVKDQIKQLE EPAVKKLKEI SDAVRKVFLL
460 470 480 490 500
LAQSSFIGFP NLLKSAKTKI EAIKQVNEST AESMLRTQFK MEMIVYTQDS
510 520 530 540 550
TYSHSLSERK REEEDDRPLP TIKIRSTIFS TDNHATLQEM MLHLKSYYRI
560 570 580 590 600
SSQRLADQIP MVIRYLVLQE FASQLQREML QTLQEKDNIE QLLKEDFDIG
610 620
SKRAALQNKL KRLMKARSYL VEF
Length:623
Mass (Da):70,895
Last modified:February 1, 1997 - v1
Checksum:i214D08A371D787A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U66475 mRNA. Translation: AAB40994.1.
BT043723 mRNA. Translation: ACH70838.1.
RefSeqiNP_001117165.1. NM_001123693.1.
XP_013988549.1. XM_014133074.1.
UniGeneiSsa.38459.
Ssa.459.

Genome annotation databases

GeneIDi100136920.
100136923.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U66475 mRNA. Translation: AAB40994.1.
BT043723 mRNA. Translation: ACH70838.1.
RefSeqiNP_001117165.1. NM_001123693.1.
XP_013988549.1. XM_014133074.1.
UniGeneiSsa.38459.
Ssa.459.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100136920.
100136923.

Organism-specific databases

CTDi4599.
4600.

Phylogenomic databases

HOVERGENiHBG008788.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR000375. Dynamin_central.
IPR001401. Dynamin_GTPase.
IPR019762. Dynamin_GTPase_CS.
IPR022812. Dynamin_SF.
IPR030381. G_DYNAMIN_dom.
IPR003130. GED.
IPR020850. GED_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11566. PTHR11566. 1 hit.
PfamiPF01031. Dynamin_M. 1 hit.
PF00350. Dynamin_N. 1 hit.
PF02212. GED. 1 hit.
[Graphical view]
PRINTSiPR00195. DYNAMIN.
SMARTiSM00053. DYNc. 1 hit.
SM00302. GED. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00410. G_DYNAMIN_1. 1 hit.
PS51718. G_DYNAMIN_2. 1 hit.
PS51388. GED. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ98990_SALSA
AccessioniPrimary (citable) accession number: Q98990
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: July 6, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.